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Advancing our understanding of T cells to improve cancer therapies

In this interview, News-Medical talks to Dr. Brendan Horton about his latest research which has shed new light on cancer and T cells.

2 Dec 2021

Impact of SARS-CoV-2 infection on testis function

A study published in the journal Nature Reviews Urology discusses the impact of coronavirus disease 2019 (COVID-19) on male fertility.

2 Dec 2021

Systematic survey of human SARS-CoV-2 monoclonal antibodies

Scientists have mined information from several research publications and patents to create a dataset of approximately 8000 human antibodies to the SARS-CoV-2 spike from more than 200 donors.

2 Dec 2021

Researchers report antibody cocktails are promising candidate tools for controlling new SARS-CoV-2 variants

Researchers from Academia Sinica in Taiwan have been investigating new antibodies that could have strong effects against SARS-CoV-2 infection.

2 Dec 2021

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

In new studies, researchers concluded that licorice triterpenoids could be candidates for anti-SARS-CoV-2 drug developments.

2 Dec 2021

Study could lead to new strategies to prevent or slow Alzheimer's disease

A gene mutation linked to Alzheimer's disease alters a signaling pathway in certain immune cells of individuals with the disease, according to a new study by scientists at Weill Cornell Medicine.

1 Dec 2021

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Researchers employ a structure-guided approach for the development of a series of ACE2-Fc variants using human IgG1 or IgG3 backbone.

1 Dec 2021

Fourth shot of Moderna COVID vaccine improves Delta variant neutralization in kidney transplant patients

New research suggests that a fourth dose of the mRNA-1273 vaccine in kidney transplant recipients improves Delta variant serum neutralization.

1 Dec 2021

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

A new study from Texas Biomedical Research Institute (Texas Biomed) and collaborators has identified a promising drug candidate to minimize uncontrolled, erratic muscle movements, called dyskinesia, associated with Parkinson's disease.

1 Dec 2021

Safety and immunogenicity of different COVID-19 booster vaccines

New study findings suggest that booster vaccination with an mRNA-based vaccine has the highest immunogenicity against the COVID-19 Delta variant.

1 Dec 2021

Structure function analysis of potent antibodies against Beta SARS-CoV-2 variant

A team of researchers from UK and US institutions created a large panel of mAbs derived from memory B cells of convalescent Beta subjects to better understand the antigenic landscape of Beta.

1 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Grouping of immunological T-cell receptors may be key to identifying patients' history of infection

Grouping of pathogen-recognizing proteins on immune T cells may be key to identifying if someone has had an infection in the past, suggests a study published today in eLife.

1 Dec 2021

Impact of SARS-CoV-2 on oral health

New research examined SARS-CoV-2 and its impact on oral health and suggests that survival against the infection may be partially dependent on such factors.

1 Dec 2021

Role of interferon type I-driven responses associated with disease control in COVID-19

New research suggests that treatment with type I interferons in the early stage of COVID-19 may supress disease progression by limiting SARS-CoV-2 in hosts.

1 Dec 2021

Study compares NAbs from natural SARS-CoV-2 infection vs. vaccine induced against symptomatic infection

Scientists have recently compared the levels of antibody concentrations in unvaccinated, SARS-CoV-2 convalescent individuals and COVID-19 specific antibodies in vaccinated individuals.

30 Nov 2021

An antiviral regimen based on biomimetic polymers for COVID-19

In a new study published on the bioRxiv* preprint server, scientists proposed the aforementioned mechanism of action (MOA) and have validated it using electron photomicrographs of murine cytomegalovirus (MCMV), which were incubated with a nanoviricide.

30 Nov 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

Prior infection with SARS-CoV-2 continues to provide protection from reinfection

Researchers from the University of Michigan investigated the correlation between SARS-CoV-2 infection and the severity of reinfections.

30 Nov 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Receptor News and Research

Advancing our understanding of T cells to improve cancer therapies

Impact of SARS-CoV-2 infection on testis function

Systematic survey of human SARS-CoV-2 monoclonal antibodies

Researchers report antibody cocktails are promising candidate tools for controlling new SARS-CoV-2 variants

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

Study could lead to new strategies to prevent or slow Alzheimer's disease

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Fourth shot of Moderna COVID vaccine improves Delta variant neutralization in kidney transplant patients

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

Safety and immunogenicity of different COVID-19 booster vaccines

Structure function analysis of potent antibodies against Beta SARS-CoV-2 variant

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

Grouping of immunological T-cell receptors may be key to identifying patients' history of infection

Impact of SARS-CoV-2 on oral health

Role of interferon type I-driven responses associated with disease control in COVID-19

Study compares NAbs from natural SARS-CoV-2 infection vs. vaccine induced against symptomatic infection

An antiviral regimen based on biomimetic polymers for COVID-19

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

Prior infection with SARS-CoV-2 continues to provide protection from reinfection

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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