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Daily circadian cycles may impact our ability to fight disease

An analysis of an exhaustive dataset on cells essential to the mammalian immune system shows that our ability to fight disease may rely more heavily on daily circadian cycles than previously assumed.

12 Jan 2021

UTSW study uncovers a gene linked to growth of breast cancer

A team of UT Southwestern researchers has identified a gene involved in the growth of breast cancer, a finding that could lead to potential new targets for treatment.

12 Jan 2021

Atmospheric particulate matter may influence the transmission and evolution of SARS-CoV-2

A recent study conducted at the University of Malta Medical School, Malta, has revealed that a drop in the level of particulate matter 2.5 (PM2.5), which are airborne pollutant particles with a diameter of 2.5 micrometer, in the atmosphere due to lockdown is associated with the arrival of a newer variant of SARS-CoV-2, which has eventually displaced the original virus after lockdown.

12 Jan 2021

Researchers determine the atomic structure of protein that helps coronavirus to evade immune cells

A team of HIV researchers, cellular biologists, and biophysicists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells.

12 Jan 2021

Stress during pregnancy could affect the baby's chance of developing multiple diseases

Stress on an expectant mother could affect her baby's chance of developing disease - perhaps even over the course of the child's life, UC researchers have found.

12 Jan 2021

Mosaic mutations during embryonic development can cause autism spectrum disorder

Two studies in today's Nature Neuroscience, led by researchers at Boston Children's Hospital, Brigham and Women's Hospital (BWH), and Harvard Medical School (HMS), implicate mosaic mutations arising during embryonic development as a cause of autism spectrum disorder (ASD). The findings open new areas for exploring the genetics of ASD and could eventually inform diagnostic testing.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

Researchers succeed in mapping the structure of virus that causes diarrhea

Researchers at Umeå University in Sweden have for the first time at the atomic level succeeded in mapping what a virus looks like that causes diarrhea and annually kills about 50,000 children in the world.

11 Jan 2021

Researchers identify biomarkers in sperm for paternal offspring autism susceptibility

Biomarkers in human sperm have been identified that can indicate a propensity to father children with autism spectrum disorder.

11 Jan 2021

SARS-CoV-2-induced innate immune responses may vary with disease severity, finds study

Scientists from Germany and China recently conducted a large meta-analysis using transcriptome data of SARS-CoV-2 to evaluate the routes of viral entry and the characteristics of innate immune responses induced by SARS-CoV-2 infection.

11 Jan 2021

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

The gut plays a central role in the regulation of the body's metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide.

11 Jan 2021

Large-scale genome sequencing shows how SARS-CoV-2 mutated

A new study published on the preprint server bioRxiv* describes the results of genomic sequencing of the virus, which may help trace the routes of transmission of the virus from person to person, and from country to country.

10 Jan 2021

Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences

In a recent bioRxiv preprint study, researchers from the University of Hawaii showed that the S gene of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously mutating according to the sequence and phylogenetic analysis.

10 Jan 2021

Modeling study sheds light on SARS-CoV-2 genome packaging

Researchers at the University of North Carolina at Chapel Hill have conducted a study exploring how the spatial patterning of certain genomic RNA regions in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promotes compaction, packaging, and cyclization of the viral genome.

10 Jan 2021

New test detects SARS-CoV-2 in less than 5 mins

A fast and accurate virus detection strategy is very crucial to reduce the rate of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for COVID-19. The global scientific research community responded to this unprecedented demand in diagnostic testing by developing several detection platforms, the most sensitive of which detect the viral RNA.

10 Jan 2021

Researchers unravel the process that makes viruses infectious

Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus 'package up' their genetic code, allowing them to infect cells.

8 Jan 2021

Single-dose nanoparticle vaccine for SARS-CoV-2

Before the pandemic, the lab of Stanford University biochemist Peter S. Kim focused on developing vaccines for HIV, Ebola and pandemic influenza.

8 Jan 2021

FDA alerts health care providers and clinical laboratory staff about SARS-CoV-2 viral mutation

The U.S. Food and Drug Administration is alerting clinical laboratory staff and health care providers that the FDA is monitoring the potential impact of viral mutations, including an emerging variant from the United Kingdom known as the B.1.1.7 variant, on authorized SARS-CoV-2 molecular tests, and that false negative results can occur with any molecular test for the detection of SARS-CoV-2 if a mutation occurs in the part of the virus's genome assessed by that test.

8 Jan 2021

Genetic blueprint provides insights into unique biology of egg-laying monotreme mammals

The genomes of egg-laying monotreme mammals, platypus and echidna, have been published in the prestigious journal Nature, providing a valuable public resource for research in mammalian biology and evolution, with applications for their conservation and health.

8 Jan 2021

International consortium awarded SNSF Sinergia grant to improve treatment for pediatric brain tumors

SNSF Sinergia grant awarded to research groups in Switzerland and Norway to identify novel treatment strategies for children with aggressive brain tumors.

7 Jan 2021

Genome News and Research

Daily circadian cycles may impact our ability to fight disease

UTSW study uncovers a gene linked to growth of breast cancer

Atmospheric particulate matter may influence the transmission and evolution of SARS-CoV-2

Researchers determine the atomic structure of protein that helps coronavirus to evade immune cells

Stress during pregnancy could affect the baby's chance of developing multiple diseases

Mosaic mutations during embryonic development can cause autism spectrum disorder

Master Regulator proteins control cancer transcriptional identity

Researchers succeed in mapping the structure of virus that causes diarrhea

Researchers identify biomarkers in sperm for paternal offspring autism susceptibility

SARS-CoV-2-induced innate immune responses may vary with disease severity, finds study

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

Large-scale genome sequencing shows how SARS-CoV-2 mutated

Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences

Modeling study sheds light on SARS-CoV-2 genome packaging

New test detects SARS-CoV-2 in less than 5 mins

Researchers unravel the process that makes viruses infectious

Single-dose nanoparticle vaccine for SARS-CoV-2

FDA alerts health care providers and clinical laboratory staff about SARS-CoV-2 viral mutation

Genetic blueprint provides insights into unique biology of egg-laying monotreme mammals

International consortium awarded SNSF Sinergia grant to improve treatment for pediatric brain tumors

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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