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How do immunocompromised patients respond to COVID-19 vaccines?

The COVID-19 vaccines produce a boost in antibody activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, new research suggests vaccine responses aren’t all created equal. Their findings showed that immunocompromised patients, such as transplant recipients, with no prior exposure to SARS-CoV-2 produce little to no neutralizing antibodies.

18 Jul 2021

Evaluation of a synthetic DNA SARS-CoV-2 vaccine INO-4800 using a nonhuman primate model

A new study published in Vaccine assesses the safety and efficacy of the synthetic DNA vaccine candidate INO-4800, delivered as a single or double dose regime.

18 Jul 2021

Infection fatality rate of COVID-19 in community-based elderly lower than earlier estimates

A new study discusses the results obtained from various seroprevalence studies conducted in 2020.

18 Jul 2021

Wildfire smoke may greatly increase susceptibility to COVID-19

Wildfire smoke may greatly increase susceptibility to SARS-CoV-2, the virus that causes COVID-19, according to new research from the Center for Genomic Medicine at the Desert Research Institute (DRI), Washoe County Health District (WCHD), and Renown Health (Renown) in Reno, Nev.

16 Jul 2021

Central amygdala micro-circuits play active role in regulation of fear responses

The brain mechanisms underlying the suppression of fear responses have attracted a lot of attention as they are relevant for therapy of human anxiety disorders.

16 Jul 2021

Sophisticated stem cell model reveals potential route of SARS-CoV-2 entry into the brain

Researchers at University of California San Diego School of Medicine and Rady Children's Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.

16 Jul 2021

Researchers isolate human monoclonal antibodies that may neutralize several norovirus variants

Researchers at Vanderbilt University Medical Center and the Baylor College of Medicine in Houston, Texas, have taken a big step toward developing targeted treatments and vaccines against a family of viruses that attacks the gastrointestinal tract.

16 Jul 2021

Broad-spectrum antibiotic no more effective than placebo in preventing COVID-19 symptoms

A UC San Francisco study has found that the antibiotic azithromycin was no more effective than a placebo in preventing symptoms of COVID-19 among non-hospitalized patients, and may increase their chance of hospitalization, despite widespread prescription of the antibiotic for the disease.

16 Jul 2021

Research shows a direct link between SUV39H2 gene and autism spectrum disorders

New research from the RIKEN Center for Brain Science in Japan shows that a deficit in histone methylation could lead to the development of autism spectrum disorders (ASD).

16 Jul 2021

UCSF researchers discover how the immune system may play a role in miscarriage

Researchers at UC San Francisco are zeroing in on how the immune system may play a role in miscarriage, which affects about a quarter of pregnancies.

16 Jul 2021

Study provides insights into vaccine acceptance and hesitancy in low- and-middle income countries

New research published in Nature Medicine reveals willingness to get a COVID-19 vaccine was considerably higher in developing countries (80% of respondents) than in the United States (65%) and Russia (30%).

16 Jul 2021

Excess caffeine intake may be linked to increased risk of osteoporosis

University of South Australia researchers have a bone to pick when it comes to drinking too much coffee as new research finds that excess caffeine may be linked to an increased risk of osteoporosis.

16 Jul 2021

New algorithm can be a more effective way to analyze models of biological systems

From biochemical reactions that produce cancers, to the latest memes virally spreading across social media, simple actions can generate complex behaviors.

16 Jul 2021

New method shows how fatty acids are absorbed by single cells

A new method developed by Institute for Systems Biology and University of California, Riverside provides new insights into cancer biology by allowing researchers to show how fatty acids are absorbed by single cells.

16 Jul 2021

Pandemic disrupted the utilization of women’s preventive health services

The COVID-19 pandemic knocked many women off schedule for important health appointments, a new study finds, and many didn't get back on schedule even after clinics reopened. The effect may have been greatest in areas where such care is already likely falling behind experts' recommendations.

16 Jul 2021

Virginia Tech researchers receive $2.7 million grant to study mosquito's biological timing

Mosquitoes may be small, but they are a formidable foe. Not only can they smell over 400 chemicals that we emit and detect the carbon dioxide we breathe out, but they can even adapt their daily behavior in response to our own.

16 Jul 2021

Gene therapy delivered into the brain may be safe, effective in treating rare neurological disorder

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

16 Jul 2021

Scientists divide all cancers into two categories

All cancers fall into just two categories, according to new research from scientists at Sinai Health, in findings that could provide a new strategy for treating the most aggressive and untreatable forms of the disease.

16 Jul 2021

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers.

16 Jul 2021

Psychiatric patients have higher odds of hospitalization and death following COVID-19

In the largest systematic review and meta-analysis to date on COVID-19 outcomes in individuals with psychiatric disorders, the odds of dying or being hospitalized following COVID-19 infection were determined to be twice as high in comparison to persons without mental disorders.

16 Jul 2021

Research News and Research

How do immunocompromised patients respond to COVID-19 vaccines?

Evaluation of a synthetic DNA SARS-CoV-2 vaccine INO-4800 using a nonhuman primate model

Infection fatality rate of COVID-19 in community-based elderly lower than earlier estimates

Wildfire smoke may greatly increase susceptibility to COVID-19

Central amygdala micro-circuits play active role in regulation of fear responses

Sophisticated stem cell model reveals potential route of SARS-CoV-2 entry into the brain

Researchers isolate human monoclonal antibodies that may neutralize several norovirus variants

Broad-spectrum antibiotic no more effective than placebo in preventing COVID-19 symptoms

Research shows a direct link between SUV39H2 gene and autism spectrum disorders

UCSF researchers discover how the immune system may play a role in miscarriage

Study provides insights into vaccine acceptance and hesitancy in low- and-middle income countries

Excess caffeine intake may be linked to increased risk of osteoporosis

New algorithm can be a more effective way to analyze models of biological systems

New method shows how fatty acids are absorbed by single cells

Pandemic disrupted the utilization of women’s preventive health services

Virginia Tech researchers receive $2.7 million grant to study mosquito's biological timing

Gene therapy delivered into the brain may be safe, effective in treating rare neurological disorder

Scientists divide all cancers into two categories

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

Psychiatric patients have higher odds of hospitalization and death following COVID-19

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