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Findings of the HITCH randomized clinical trial show lack of improvement in COVID-19 on temporary androgen suppression

Researchers investigated whether temporary androgen suppression by degarelix improved the clinical outcomes among male patients hospitalized with COVID-19.

27 Apr 2022

Bebtelovimab potently neutralizes all SARS-CoV-2 variants of concern

The current study, escribes a new mAb LY-CoV1404 (bebtelovimab) from Eli Lilly, with high neutralization potency with a broad spectrum of activity across all current variants.

27 Apr 2022

The effect of antidepressants on patient-reported health-related quality of life

A new study published in PLoS ONE aimed to investigate the effect of using antidepressant medications on the HRQoL of patients with depression.

27 Apr 2022

Highly Effective Single-Dose HPV Vaccination for the Eradication of Cervical Cancer

In this interview, News-Medical speaks to Dr. Ruanne Barnabas about the KEN She study which found that a single-dose Human Papillomavirus (HPV) vaccination was effective in preventing incident persistent oncogenic HPV infection.

27 Apr 2022

Cellular reprogramming can lead to better liver tissue regeneration in mice

Mammals can't typically regenerate organs as efficiently as other vertebrates, such as fish and lizards. Now, Salk scientists have found a way to partially reset liver cells to more youthful states - allowing them to heal damaged tissue at a faster rate than previously observed.

27 Apr 2022

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

A team led by the Institut de Neurociències at the Universitat Autònoma de Barcelona managed to reduce chronic inflammation associated with multiple sclerosis in mice thanks to the administration of a type of lipid that mediates inflammation.

27 Apr 2022

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

Research highlights importance of booster vaccine doses to protect against all Omicron variants

In a recent study published in the Cell Host and Microbe journal, researchers examined the neutralization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1, BA.1.1, and BA.2 sublineages.

27 Apr 2022

Well-established group of antimalarials unlikely to be affected by resistance, study shows

New research published today in Antimicrobial Agents and Chemotherapy, shows that the well-established group of antimalarials, known as artemisinins, are unlikely to be affected by resistance.

26 Apr 2022

mRNA booster vaccination found to protect aged mice against the Omicron variant of SARS-CoV-2

A new study examined the protective effect of the mRNA booster vaccine against the SARS-CoV-2 Omicron variant in 21-month-old mice.

26 Apr 2022

Phase I/II trials of new paratyphoid vaccine begin in Oxford

The University of Oxford in collaboration with the University of Maryland School of Medicine has begun recruiting for a Phase I/II trial of a new paratyphoid vaccine in human volunteers in Oxford - with first vaccinations taking place today (Tuesday).

26 Apr 2022

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Researchers developed a highly pathogenic mouse-adapted SARS-CoV-2 strain to model mild, moderate, or COVID-19.

26 Apr 2022

Eradicating Polio; What's it going to take?

In this interview, we speak to Judith Diment from Rotary’s International PolioPlus Committee about the incredible work they are doing to help eradicate polio worldwide.

26 Apr 2022

Dotmatics, previously Insightful Science, set to transform the future of scientific software and data management

Dotmatics was today announced as the formal name and brand for the combined entities of Insightful Science and Dotmatics.

From Dotmatics 26 Apr 2022

Effectiveness of CoronaVac, AZD1222, and BNT162b2 vaccine boosters

The researchers assessed the efficacy of homologous and heterologous booster doses of SARS-CoV-2 vaccines.

26 Apr 2022

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

First product within new ‘in-a-box’ range, which harnesses next-generation, human-relevant Liver-on-a-Chip technology to improve the accuracy and efficiency of NASH drug discovery.

From CN Bio 26 Apr 2022

As vaccination coverage increases, SARS-CoV-2 genetic diversity decreases

In a recent letter to the editor published in the Journal of Infection, researchers from the Chinese PLA Center for Disease Control and Prevention observed that the genetic diversity of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could be suppressed by high coverage of vaccination.

25 Apr 2022

ACT-based program is an effective treatment for reducing criminal behavior, study finds

A new study from Iowa State University found men convicted of domestic violence were charged with significantly fewer violent and nonviolent charges one year after completing a treatment program developed in Iowa compared to a model used in most other states.

25 Apr 2022

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

The development of the anti-cancer immunotherapy drugs called immune checkpoint inhibitors has improved treatment for many cancer patients, but patients with mucosal melanomas - melanomas that occur not on the skin but in the mucous membranes in the head, neck, eyes, respiratory tract, and genitourinary region - are particularly resistant to immune checkpoint inhibitors for reasons researchers don't fully understand.

25 Apr 2022

Treating COVID-19 using monoclonal antibodies during pregnancy

Researchers assessed the efficiency efficacy and safety of monoclonal antibodies for treating SARS-CoV-2 during pregnancy.

25 Apr 2022

Efficacy News and Research

Findings of the HITCH randomized clinical trial show lack of improvement in COVID-19 on temporary androgen suppression

Bebtelovimab potently neutralizes all SARS-CoV-2 variants of concern

The effect of antidepressants on patient-reported health-related quality of life

Highly Effective Single-Dose HPV Vaccination for the Eradication of Cervical Cancer

Cellular reprogramming can lead to better liver tissue regeneration in mice

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Research highlights importance of booster vaccine doses to protect against all Omicron variants

Well-established group of antimalarials unlikely to be affected by resistance, study shows

mRNA booster vaccination found to protect aged mice against the Omicron variant of SARS-CoV-2

Phase I/II trials of new paratyphoid vaccine begin in Oxford

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Eradicating Polio; What's it going to take?

Dotmatics, previously Insightful Science, set to transform the future of scientific software and data management

Effectiveness of CoronaVac, AZD1222, and BNT162b2 vaccine boosters

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

As vaccination coverage increases, SARS-CoV-2 genetic diversity decreases

ACT-based program is an effective treatment for reducing criminal behavior, study finds

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

Treating COVID-19 using monoclonal antibodies during pregnancy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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