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COVID-19 severity could be linked to genetic variance

A new study describes some potentially important genetic factors in the host that may shape the clinical symptoms and signs of the disease.

23 Dec 2020

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers claim to have reproduced disease mechanisms due to coronavirus disease 2019 (COVID-19) in the fruit fly, Drosophila, while also providing proof of the efficacy of one drug against these disease processes. If validated, these findings represent a new understanding of how the virus causes neurological symptoms that could help develop more effective therapies.

23 Dec 2020

Nanoplastics affect composition and diversity of human intestinal microbiome

We live in a world invaded by plastic. Its role as a chemically stable, versatile and multi-purpose fostered its massive use, which has finally translated into our current situation of planetary pollution.

22 Dec 2020

Clinical psychologist evaluates the dangers of race-based norms in cognitive testing

A UCSF clinical psychologist has taken aim at the National Football League (NFL) for "race norming" black players diagnosed with dementia, a practice that is depriving them of the monetary awards allocated to former footballers with neurodegenerative disorders.

22 Dec 2020

Novel 3D maps show how genes interact in several types of immune cells

The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.

22 Dec 2020

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

For over 20 years, the Genetics Service at the KK Women's and Children's Hospital (KKH) has been providing clinical care to patients with genetic disorders.

22 Dec 2020

Study highlights the far-reaching effects of mutagenic compounds on human health

In order to survive, flourish and successfully reproduce, organisms rely on a high degree of genetic stability. Mutagenic agents, which can threaten the integrity of the genetic code by causing mutations in DNA, pose a serious risk to human health.

21 Dec 2020

Stem cell engineering used to identify gene signaling pathway linked to schizophrenia

Using human-induced pluripotent stem cells engineered from a single family's blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered by scientists at The University of Texas Health Science Center at Houston.

21 Dec 2020

Scientists map direct interactions between SARS-CoV-2 RNA and human host cells

Scientists from Würzburg and the US have charted the first global atlas of direct interactions between SARS-CoV-2 RNA and human host cells. This may provide a starting point for novel treatments.

21 Dec 2020

Many US health experts underestimated the coronavirus … until it was too late

A year ago, while many Americans were finishing their holiday shopping and finalizing travel plans, doctors in Wuhan, China, were battling a mysterious outbreak of pneumonia with no known cause.

21 Dec 2020

COVID-19 spread in cities driven by socioeconomically weaker groups, study finds

Researchers in Sweden have conducted a study showing that the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within cities is driven by socioeconomically weaker and high-mobility groups. They used Basel, Switzerland as their case study.

21 Dec 2020

SARS-CoV-2 spike protein remains remarkably conserved among 37 variants from Hong Kong

As the coronavirus disease 2019 (COVID-19) pandemic continues to intensify in many parts of the world, vaccine development is proceeding apace.

21 Dec 2020

South Korean city shows SARS-CoV-2 clade shift from V to GH over time

A new paper from South Korea describes the evolving SARS-CoV-2 genome in a single city, that of Gwangju, in the southwestern region of this country.

21 Dec 2020

Detecting SARS-CoV-2 sequences in blood monocytes

A meeting with doctors from Wuhan presented a compelling observation to Professor Laura Manuelidis, MD, from the Yale Medical School early in 2020.

21 Dec 2020

Research may lead to better treatment and vaccines for Ebola, COVID-19

In the midst of a global pandemic with COVID-19, it's hard to appreciate how lucky those outside of Africa have been to avoid the deadly Ebola virus disease.

21 Dec 2020

New understanding of physical properties of chromatin may show how genome is encoded and decoded

University of Alberta researchers have found an answer to a fundamental question in genomic biology that has eluded scientists since the discovery of DNA: Within the nucleus of our cells, is the complex package of DNA and proteins called chromatin a solid or a liquid?

20 Dec 2020

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

There is light at the end of the COVID-19 pandemic tunnel. Several vaccines against the SARS-CoV-2 virus that causes COVID-19 are now in clinical trials, with one -- developed by Pfizer/BioNTech -- already having been approved for emergency use in the United States.

18 Dec 2020

Genome News and Research

COVID-19 severity could be linked to genetic variance

Researchers use fruit fly model to understand COVID-19-related neurological complications

Nanoplastics affect composition and diversity of human intestinal microbiome

Clinical psychologist evaluates the dangers of race-based norms in cognitive testing

Novel 3D maps show how genes interact in several types of immune cells

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

Study highlights the far-reaching effects of mutagenic compounds on human health

Stem cell engineering used to identify gene signaling pathway linked to schizophrenia

Scientists map direct interactions between SARS-CoV-2 RNA and human host cells

Many US health experts underestimated the coronavirus … until it was too late

COVID-19 spread in cities driven by socioeconomically weaker groups, study finds

SARS-CoV-2 spike protein remains remarkably conserved among 37 variants from Hong Kong

South Korean city shows SARS-CoV-2 clade shift from V to GH over time

Detecting SARS-CoV-2 sequences in blood monocytes

Research may lead to better treatment and vaccines for Ebola, COVID-19

New understanding of physical properties of chromatin may show how genome is encoded and decoded

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

Cell atlas helps better understand the biology of tropical disease parasite

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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