Molecule News and Research

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No more tears: immunization without needles

A new study published in the Journal of Investigative Dermatology reports a novel skin vaccine patch which could help effective and safe immunization by disrupting the permeability of the skin, providing a convenient and non-invasive alternative to immunization shots. This innovative technique now needs to be tested in humans.

17 Sep 2019

Uncovering new T cell regulatory processes could help treat autoimmune disease

One of the important cells involved in the immune response is the T follicular helper (Tfh) cell. These are important in the normal process of antibody production following immunization, for instance. However, they are also abnormally increased in number in patients with autoimmune disease, such as systemic lupus erythematosus.

16 Sep 2019

Stanford-UCSF researchers report new cure for common cold in human cells and mice

Temporarily disabling a single protein inside our cells might be able to protect us from the common cold and other viral diseases, according to a study led by researchers at Stanford University and University of California-San Francisco.

16 Sep 2019

Brain activity intensity appears to increase our need for sleep

The intensity of brain activity during the day, notwithstanding how long we've been awake, appears to increase our need for sleep, according to a new UCL study in zebrafish.

16 Sep 2019

New platform uses nanoparticles to deliver anti-cancer agent to cells

Scientists from the University of Cambridge have developed a platform that uses nanoparticles known as metal-organic frameworks to deliver a promising anti-cancer agent to cells.

16 Sep 2019

Accelerating drug discovery process to help patients

An international research team has developed a new strategy that can predict the potential clinical implications of new therapeutic compounds based on simple cellular responses.

15 Sep 2019

Newly developed nanomaterial is both twisted and untwisted at the same time

A new nanomaterial developed by scientists at the University of Bath could solve a conundrum faced by scientists probing some of the most promising types of future pharmaceuticals.

15 Sep 2019

Nano-sized bubbles in our body could effectively fight cancer

Healthy cells in our body release nano-sized bubbles that transfer genetic material such as DNA and RNA to other cells. It's your DNA that stores the important information necessary for RNA to produce proteins and make sure they act accordingly.

15 Sep 2019

New reaction enables edition of organic molecule's skeletons

Since Friedrich Wohler synthesized urea (by accident) back in 1828, chemical synthesis - and organic synthesis for that - has been a driving force in pharmaceutical innovation.

13 Sep 2019

Editing away cancer and HIV in China: win or lose?

Scientists in China recently edited out the CCR5 gene from a patient with HIV's stem cells, but the research has sparked ethical debate.

13 Sep 2019

Discovery opens up new opportunities to understand the genetics of cancer

University of Delaware molecular biologist Mona Batish and collaborators at Harvard Medical School and University of California, Los Angeles, have identified a new circular ribonucleic acid (RNA) that increases tumor activity in soft tissue and connective tissue tumors.

13 Sep 2019

Scientists identify a potentially novel avenue to treat non-small cell lung cancers

Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers.

13 Sep 2019

Promising new drug being developed for polycystic kidney disease

Researchers have developed a potential new drug for the treatment of Polycystic kidney disease (PKD) – a deadly genetic condition affecting the kidneys that leads to formation of swellings or cysts within the kidney that cause it to fail.

12 Sep 2019

Study provides new insights into how astrocytes help the brain process information

A collaboration between the laboratories of Vincent Bonin (NERF, empowered by VIB, imec and KU Leuven) and Matthew Holt (VIB-KU Leuven Center for Brain & Disease Research) reveals that noradrenaline plays a key role in how astrocytes - star-shaped cells in the brain closely associated with neurons - track distinct information during behavior.

12 Sep 2019

Deadly infections on the rise: New classes of antibiotics are desperately needed

Globally, the number of deaths from infections is on the rise as more bacteria become resistant to antibiotics.

12 Sep 2019

Malarial treatment from Antarctic sea sponge

Malaria, which ravages hot tropical areas, could be treated effectively using a protein extracted from an Antarctic sponge.

12 Sep 2019

Scientists identify molecule that plays key role in determining fate of cells under stress

St. Jude Children's Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum.

12 Sep 2019

Insulin drug could treat glioblastoma

A research team from the University of Georgia's Regenerative Bioscience Center has found that a compound molecule used for drug delivery of insulin could be used to treat glioblastoma, an aggressive, usually fatal form of brain cancer.

12 Sep 2019

Calcium channel blockers may help effectively treat memory loss in Alzheimer's disease

Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood.

11 Sep 2019

Gene coding error likely responsible for rare form of inherited 'short telomere' disease

By combing through the entire genetic sequences of a person with a lung scarring disease and 13 of the person’s relatives, Johns Hopkins Medicine researchers say they have found a coding error in a single gene that is likely responsible for a rare form of the disease and the abnormally short protective DNA caps on chromosomes long associated with it.

From Johns Hopkins Medicine 11 Sep 2019