Biochemistry News and Research

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Small molecules reverse protein trafficking and mitochondrial dysfunction in Parkinson's disease models

Parkinson's disease is a neurodegenerative disorder characterized by tremors, muscle rigidity, and slowed movements. There is currently no cure for the disease, and current Parkinson's therapies only address disease symptoms, not the disease's cellular cause.

29 Dec 2009

Test tube experiments show slight changes in protein chemistry can eliminate Huntington's disease in mice

In Huntington's disease, a mutated protein in the body becomes toxic to brain cells. Recent studies have demonstrated that a small region adjacent to the mutated segment plays a major role in the toxicity. Two new studies supported by the National Institutes of Health show that very slight changes to this region can eliminate signs of Huntington's disease in mice.

28 Dec 2009

Enzyme dCK plays a profound role in normal lymphocyte development

Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center.

23 Dec 2009

WuXi PharmaTech announces winners of third Life Science and Chemistry Awards

WuXi PharmaTech, a leading pharmaceutical, biotechnology, and medical-device research and development outsourcing company with operations in China and the United States, today announced the winners of its third Life Science and Chemistry Awards, held on December 20, 2009, at the China World Hotel in Beijing.

23 Dec 2009

Guardian Technologies International meets and presents SM TBDx to Indian healthcare officials

Tuberculosis (TB) continues to be a serious global pandemic health threat with more than 9 million new cases diagnosed annually. TB is a leading cause of mortality in India, killing nearly 1,000 people each day.

23 Dec 2009

Tel Aviv University's new Genome Analyzer fuels research dreams and tomorrow's cures

To identify the hemophilia mutation that affected Queen Victoria and her European relatives, scientific detectives used a cutting-edge "deep sequencing tool." Able to trace rare genetic disease mutations, the tool can turn a single laboratory into a fertile genetic research center.

22 Dec 2009

Proline repeats make teeth strong and resilient

A simple amino acid that is repeated in the center of proteins found in tooth enamel makes teeth stronger and more resilient, according to new research at the University of Illinois at Chicago.

22 Dec 2009

Findings may help develop new antiviral drugs for influenza

Investigators at Burnham Institute for Medical Research (Burnham), Mount Sinai School of Medicine (Mount Sinai), the Salk Institute for Biological Studies (Salk) and the Genomics Institute of the Novartis Research Foundation (GNF) have identified 295 human cell factors that influenza A strains must harness to infect a cell, including the currently circulating swine-origin H1N1.

22 Dec 2009

Investigation of IDH1 gene mutations in brain cancer receives new funds

Agios Pharmaceuticals, the leading biopharmaceutical company focused on discovering and developing novel drugs in the emerging field of cancer metabolism, announced today that it has received funding from Accelerate Brain Cancer Cure (ABC2), a non-profit organization that supports brain cancer research. ABC2’s funding will enable new research investigating IDH1 gene mutations in brain cancer, with the goal of supplementing Agios’s ongoing research into the development of new IDH1 therapeutics and diagnostics.

21 Dec 2009

Researchers determine structures of two enzymes that customize histones

Researchers at Emory University School of Medicine have determined the structures of two enzymes that customize histones, the spool-like proteins around which DNA coils inside the cell.

20 Dec 2009

UCLA CNSI and NOF collaborate in novel technologies for nanodelivery of drug therapies

The California NanoSystems Institute at UCLA has announced a new collaboration with Japan-based NOF Corp. to explore initiatives in nanotherapeutics research for new drug-delivery systems.

19 Dec 2009

White paper discussing investment opportunities related to the U.S. healthcare reform released

Rockefeller and Company - a leading global wealth management firm serving high-net-worth individuals, families, trusts, foundations and endowments - today released "The Investment Opportunities in Healthcare Reform," a white paper discussing the compelling investment opportunities related to the U.S. healthcare reform initiative.

18 Dec 2009

Researchers discover how protein can be controlled and under what circumstances it can go awry

A team of researchers studying the protein that, when defective or absent, causes cystic fibrosis (CF) has made an important discovery about how that protein is normally controlled and under what circumstances it might go awry.

18 Dec 2009

2010 Dr. Paul Janssen Award for Biomedical Research open for nomination

The Dr. Paul Janssen Award for Biomedical Research has opened the 2010 call for nominations. The $100,000 Award recognizes individuals whose efforts have made significant transformational contributions towards the improvement of human health. Nomination forms are available at pauljanssenaward.com and will be accepted until February 15, 2010.

18 Dec 2009

Access to convenience stores can pormote childhood obesity

Childhood obesity is directly related to how close kids live to convenience stores, according to the preliminary findings of a major Canadian study presented at the Entretiens Jacques-Cartier in Lyon, France. The ongoing study is named QUALITY for Quebec Adipose and Lifestyle InvesTigation in Youth.

18 Dec 2009

Calorie-intake restriction can benefit longevity and help prevent cancer

Researchers from the University of Alabama at Birmingham (UAB) have discovered that restricting consumption of glucose, the most common dietary sugar, can extend the life of healthy human-lung cells and speed the death of precancerous human-lung cells, reducing cancer's spread and growth rate.

18 Dec 2009

Triad Isotopes enters into agreement to acquire the U.S. radiopharmacy network

Triad Isotopes, Inc., a portfolio company of Parthenon Capital Partners, today announced that it has entered into an agreement to acquire the U.S. radiopharmacy network currently owned and operated by Covidien, a leading global healthcare products company based in Dublin, Ireland.

18 Dec 2009

People with higher Leptin levels have significantly reduced incidence of AD and dementia

This week’s issue of the Journal of the American Medical Association (Dec 16) features a report on a long-term, prospective study of elderly, dementia-free individuals led by researchers from Boston University School of Medicine and the Framingham Heart Study focusing on the association between the protein hormone Leptin and the risk of developing Alzheimer’s disease (AD).

17 Dec 2009

Diet rich in omega-3 fatty acids linked to improved nervous-system function

The omega-3 essential fatty acids commonly found in fatty fish and algae help animals avoid sensory overload, according to research published by the American Psychological Association.

17 Dec 2009

Deaths from heart disease peak in December and January, US database reveals

'Tis the season… for a heart attack? According to Dr. Keith Churchwell, associate director of the Vanderbilt Heart and Vascular Institute at Vanderbilt University Medical Center, a US database of 53 million deaths occurring between 1973 and 2001 reveals that deaths from heart disease peak in December and January, with spikes on Christmas and New Year's Day.

16 Dec 2009

Biochemistry News and Research

Small molecules reverse protein trafficking and mitochondrial dysfunction in Parkinson's disease models

Test tube experiments show slight changes in protein chemistry can eliminate Huntington's disease in mice

Enzyme dCK plays a profound role in normal lymphocyte development

WuXi PharmaTech announces winners of third Life Science and Chemistry Awards

Guardian Technologies International meets and presents SM TBDx to Indian healthcare officials

Tel Aviv University's new Genome Analyzer fuels research dreams and tomorrow's cures

Proline repeats make teeth strong and resilient

Findings may help develop new antiviral drugs for influenza

Investigation of IDH1 gene mutations in brain cancer receives new funds

Researchers determine structures of two enzymes that customize histones

UCLA CNSI and NOF collaborate in novel technologies for nanodelivery of drug therapies

White paper discussing investment opportunities related to the U.S. healthcare reform released

Researchers discover how protein can be controlled and under what circumstances it can go awry

2010 Dr. Paul Janssen Award for Biomedical Research open for nomination

Access to convenience stores can pormote childhood obesity

Calorie-intake restriction can benefit longevity and help prevent cancer

Triad Isotopes enters into agreement to acquire the U.S. radiopharmacy network

People with higher Leptin levels have significantly reduced incidence of AD and dementia

Diet rich in omega-3 fatty acids linked to improved nervous-system function

Deaths from heart disease peak in December and January, US database reveals

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