Clinical Trial News and Research

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BAT advances COVID-19 vaccine candidate into phase-I clinical trial

The COVID-19 vaccine candidate (KBP-COVID-19; NCT04473690) will become one of a number of potential vaccines to have progressed beyond pre-clinical testing.

16 Dec 2020

New data shows encouraging results for patients with neuro-degenerative blinding eye disease

New data published in the Journal Science Translational Medicine shows encouraging results in a worldwide clinical trial for patients diagnosed with the neuro-degenerative blinding eye disease; Leber Hereditary Optic Neuropathy (LHON.)

16 Dec 2020

Researchers identify adenovirus gene therapy for placental insufficiency

A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency, as reported in the peer-reviewed journal Human Gene Therapy.

15 Dec 2020

Research could lead to potential new treatments for mutant RAS-driven cancers

Scientists have dedicated huge amounts of time and resources to better understanding the causes and mechanisms of cancer growth.

15 Dec 2020

Resistance training and peanut protein supplementation positively affect muscle health in older adults

Declines in muscle mass and strength can begin in early adulthood, unnoticeable at first, and eventually progress until functionality, endurance, and general health may be compromised.

15 Dec 2020

Phase 2 clinical trial at UCR to test first-in-class drug for treatment of stuttering

The School of Medicine at the University of California, Riverside, will serve as lead site for a Phase 2 clinical trial evaluating ecopipam, an investigational first-in-class drug being tested for the treatment of stuttering in adults and Tourette syndrome in pediatric patients.

15 Dec 2020

Surgical and drug treatment approaches are equally effective for diabetic eye disease

Surgical and injectable drug approaches are equally effective for treatment of bleeding inside the eye from proliferative diabetic retinopathy (PDR), according to a National Eye Institute (NEI)-supported clinical study from the DRCR Retina Network (DRCR.net).

15 Dec 2020

Drug may increase vaccine protection in older adults

A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in eLife shows.

15 Dec 2020

Pediatricians want kids to be part of COVID vaccine trials

If clinical trials for COVID-19 vaccines aren't expanded soon to include children, it's unlikely that even kids in their teens will be vaccinated in time for the next school year.

15 Dec 2020

Single-dose radiation therapy may lessen, eliminate unsafe additional outside trips during the pandemic

According to recent studies, an increase in the COVID-19 positivity rate correlates to an increase in mortality from non-coronavirus-related diseases.

14 Dec 2020

Eureka's InvisiMask human antibody nasal spray offers protection against SARS-CoV-2 in mice

Eureka Therapeutics, Inc. announced today successful preclinical results from its InvisiMask™ Human Antibody Nasal Spray in mice, which offers protection against SARS-CoV-2 S pseudotyped virus infection for up to 10 hours.

14 Dec 2020

Researchers examine whether regenerative patch for spina bifida defect can promote healing

Researchers are investigating whether a human umbilical cord patch placed on the spina bifida defect could improve healing after minimally invasive fetoscopic surgery in a clinical trial at The University of Texas Health Science Center at Houston.

14 Dec 2020

Mindfulness-based stress reduction may provide benefit to people with migraine

Migraine is a neurological disease that can be severely debilitating and is the second leading cause of disability worldwide.

14 Dec 2020

Remdesivir likely to be highly effective treatment for COVID-19

The drug remdesivir is likely to be a highly effective antiviral against SARS-CoV-2, according to a new study by a team of UK scientists.

14 Dec 2020

COVID-19 vaccination may potentially cut hospitalizations, deaths by 60% in Ontario, Canada

A new study suggests an impact of the COVID-19 vaccine on SARS-CoV-2 attack rate, and hospitalizations, even with no protection against infection.

14 Dec 2020

60-second breath test to detect COVID-19 with IONICON PTR-TOFMS

Singapore start-up develops fast breath test based on PTR-TOF technology.

From Ionicon Analytik Ges.m.b.H. 14 Dec 2020

Combination of baricitinib and remdesivir could benefit some COVID-19 patients

The combination of baricitinib, an anti-inflammatory drug, and remdesivir, an antiviral, reduced time to recovery for people hospitalized with COVID-19, according to clinical trial results published in the New England Journal of Medicine.

11 Dec 2020

First patient participates in immunotherapy trial despite COVID-19 pandemic

Since 2016, Bernard Thurman has undergone traditional treatments, experimental therapies and surgeries to counter the cancer within him, but nothing has successfully eradicated the disease.

11 Dec 2020

Osteoporosis drug also promotes infiltration of immune cells in breast tumors

The team of Eva González-Suarez, from the CNIO and IDIBELL, and the team of Christos Sotiriou, from the Jules Bordet Institute, demonstrate that a drug already used to treat osteoporosis promotes the infiltration of immune cells in breast tumors.

10 Dec 2020

Largest-ever study finds low complication rates in children who wear soft contact lenses

The largest-ever retrospective study of its kind has found very low complication rates in children who wear soft contact lenses, similar to rates in adults.

10 Dec 2020

Clinical Trial News and Research

BAT advances COVID-19 vaccine candidate into phase-I clinical trial

New data shows encouraging results for patients with neuro-degenerative blinding eye disease

Researchers identify adenovirus gene therapy for placental insufficiency

Research could lead to potential new treatments for mutant RAS-driven cancers

Resistance training and peanut protein supplementation positively affect muscle health in older adults

Phase 2 clinical trial at UCR to test first-in-class drug for treatment of stuttering

Surgical and drug treatment approaches are equally effective for diabetic eye disease

Drug may increase vaccine protection in older adults

Pediatricians want kids to be part of COVID vaccine trials

Single-dose radiation therapy may lessen, eliminate unsafe additional outside trips during the pandemic

Eureka's InvisiMask human antibody nasal spray offers protection against SARS-CoV-2 in mice

Researchers examine whether regenerative patch for spina bifida defect can promote healing

Mindfulness-based stress reduction may provide benefit to people with migraine

Remdesivir likely to be highly effective treatment for COVID-19

COVID-19 vaccination may potentially cut hospitalizations, deaths by 60% in Ontario, Canada

60-second breath test to detect COVID-19 with IONICON PTR-TOFMS

Combination of baricitinib and remdesivir could benefit some COVID-19 patients

First patient participates in immunotherapy trial despite COVID-19 pandemic

Osteoporosis drug also promotes infiltration of immune cells in breast tumors

Largest-ever study finds low complication rates in children who wear soft contact lenses

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