Diagnostic News and Research

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AI model aids early detection of severe COVID-19 infection in children

Children have been less impacted by COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SAR-CoV-2) than adults. But some children diagnosed with SARS-CoV-2 have experienced severe illnesses, including Multisystem Inflammatory Syndrome (MIS-C) and respiratory failure; nearly 80% of children with MIS-C become critically ill with a 2 to 4% mortality rate.

5 Feb 2021

Gene panel test enables highly accurate diagnosis of liposarcomas

Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma.

5 Feb 2021

Natural reinfection with respiratory syncytial virus varies based on antibody response

Researchers at Baylor College of Medicine found that while most individuals responded to respiratory syncytial virus (RSV) natural reinfection with a typical sustained antibody response associated with protection, a few individuals surprisingly responded atypically, not being able to sustain the antibody response, which declined to levels that made the individuals susceptible to RSV reinfection.

5 Feb 2021

GSA experts propose strategies to address dementia-related psychosis

A new white paper from The Gerontological Society of America (GSA) highlights the variety of challenges that persons with dementia-related psychosis and their caregivers have encountered during moves through different health care settings -- and proposes strategies to address these challenges.

5 Feb 2021

European Union funds new project to improve personalized treatments for ovarian cancer

The European Union has funded a project to improve personalized treatments for ovarian cancer with nearly 15 million euros for five years. The international DECIDER project has partners from 14 organizations in seven EU countries.

5 Feb 2021

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

A healthy person has a general balance of good and bad bacteria. But that balance is thrown off when someone gets sick.

5 Feb 2021

Better design of deep learning studies can lead to faster transformation of medical practices

A new Perspective article in Nature Reviews Cancer discusses reasons for the moderate progress and describes remedies designed to facilitate the transition to the clinic.

5 Feb 2021

Researchers to create computational models to improve treatments for ovarian cancer

The 5-year research project involves 14 organizations in seven EU countries and is funded by €15 M from the EU.

4 Feb 2021

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

A new preprint research paper posted to the bioRxiv server reports the development of highly effective neutralizing nanobodies targeting the viral receptor-binding domain (RBD), thus disrupting its engagement with the host cell angiotensin-converting enzyme 2 (ACE2) receptor.

4 Feb 2021

New technology could accelerate development of on-chip diagnostic techniques

New technology developed by the University of Bristol has the potential to accelerate uptake and development of on-chip diagnostic techniques in parts of the world where rapid diagnoses are desperately needed to improve public health, mortality and morbidity.

4 Feb 2021

NeuroVision Imaging receives ADDF funding to develop biomarker tests for Alzheimer's disease

NeuroVision Imaging Inc., announced today it has received an investment from the Alzheimer's Drug Discovery Foundation to support developing reliable, affordable biomarker tests for Alzheimer's disease and other forms of dementia and neurodegenerative disorders.

3 Feb 2021

One in every 30 school-aged children may have brain-related vision problems

A brain-related visual impairment, which until recently was thought to be rare, may affect one in every 30 children according to new research investigating the prevalence of Cerebral Visual Impairment [CVI].

3 Feb 2021

Genetic changes linked to neurodevelopmental disabilities, cerebral palsy

Researchers have discovered a strong link between genetic changes known to cause neurodevelopmental disabilities and cerebral palsy.

2 Feb 2021

Rapid SARS-CoV-2 antigen test improved with silver amplification

A new preprint posted to the medRxiv server describes the use of silver amplification technology to develop a sensitive, rapid antigen test for COVID-19.

2 Feb 2021

Breast cancer‐on‐a‐chip to test the effectiveness of checkpoint inhibitor drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins."

2 Feb 2021

Researchers develop rapid COVID-19 diagnostic test affordable for low-income families

A test that detects antibodies to the novel coronavirus in 10 minutes and costs only a fifth of the market average has been developed by researchers at the University of São Paulo's São Carlos Chemistry Institute and Brazilian startup Biolinker, with São Paulo Research Foundation - FAPESP's support.

2 Feb 2021

Decision-support tool may help clinicians to appropriately treat children with diarrhea

A decision-support tool that could be accessed via mobile devices may help clinicians in lower-resource settings avoid unnecessary antibiotic prescriptions for children with diarrhea, a study published today in eLife shows.

2 Feb 2021

Study identifies triggers for acute decompensation of liver cirrhosis

Chronic liver disease and even cirrhosis can go unnoticed for a long time because many patients have no symptoms: the liver suffers silently.

2 Feb 2021

Delaying colonoscopy after an abnormal stool test can have major consequences

A new Veterans Affairs study finds that delays in undergoing colonoscopy following an abnormal stool test increase the risk of a colorectal cancer diagnosis and cancer-related death.

2 Feb 2021

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

Researchers have explored heritable factors, age and body mass on temperature variation between humans. One notable finding is that the current threshold for detecting fever in older adults may be too high, precluding the ability to detect COVID-19 early on

2 Feb 2021

Diagnostic News and Research

AI model aids early detection of severe COVID-19 infection in children

Gene panel test enables highly accurate diagnosis of liposarcomas

Natural reinfection with respiratory syncytial virus varies based on antibody response

GSA experts propose strategies to address dementia-related psychosis

European Union funds new project to improve personalized treatments for ovarian cancer

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

Better design of deep learning studies can lead to faster transformation of medical practices

Researchers to create computational models to improve treatments for ovarian cancer

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

New technology could accelerate development of on-chip diagnostic techniques

NeuroVision Imaging receives ADDF funding to develop biomarker tests for Alzheimer's disease

One in every 30 school-aged children may have brain-related vision problems

Genetic changes linked to neurodevelopmental disabilities, cerebral palsy

Rapid SARS-CoV-2 antigen test improved with silver amplification

Breast cancer‐on‐a‐chip to test the effectiveness of checkpoint inhibitor drugs

Researchers develop rapid COVID-19 diagnostic test affordable for low-income families

Decision-support tool may help clinicians to appropriately treat children with diarrhea

Study identifies triggers for acute decompensation of liver cirrhosis

Delaying colonoscopy after an abnormal stool test can have major consequences

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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