Protein C News and Research

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UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

In 2012, University of Alabama at Birmingham researcher Anath Shalev, M.D., reported that a decades-old blood pressure medication called verapamil completely reversed diabetes in animal models.

25 Aug 2023

Researchers discover new therapeutic approach for neuroblastoma

Neuroblastomas are tumors of the nervous system. They can form in many places in the body and are the most common cause of cancer-related deaths in young children.

25 Aug 2023

Semaglutide could be a game-changer for patients with HFpEF and obesity

Semaglutide improves heart failure-related symptoms and physical function and results in greater weight loss compared with placebo in patients with heart failure with preserved ejection fraction (HFpEF) and obesity, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

UK Biobank Dementia Risk Score outperforms other widely used scores

A new dementia risk score, which draws on 11 mostly modifiable risk factors, identifies people at risk—from mid-life onwards—of developing the disease within the next 14 years, suggests a large long-term study published in the open access journal BMJ Mental Health.

25 Aug 2023

Researchers discover how proteins regulate 'treadmilling' in cells

Researchers at the Centre for Genomic Regulation (CRG) have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.

25 Aug 2023

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing.

25 Aug 2023

MFGM and milk protein may improve physical functioning of the elderly, study shows

Leading Finnish dairy company Valio collaborated with top nutritional scientists in a new study about the effects of MFGM and milk protein on the physical functioning of the elderly. The results show significant improvement in balance and physical performance even without an exercise intervention.

25 Aug 2023

Novavax's protein-based COVID vaccine induces broad functional immune response against XBB subvariants, data shows

Novavax, Inc., a global company advancing protein-based vaccines with its novel Matrix-M™ adjuvant, today announced that its updated protein-based XBB COVID vaccine candidate induced neutralizing antibody responses to the EG.5.1 and XBB.1.16.6 subvariants in small animal and non-human primate studies.

25 Aug 2023

Researchers develop new, modular strategy for T-cell-based immunotherapy

Immunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively.

25 Aug 2023

Midnolin protein plays key role in breaking down short-lived nuclear proteins

Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense.

24 Aug 2023

New research sheds light on role of KRAS mutations in pancreatic cancer

Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for early- and late-stage KRAS G12D-mutant pancreatic cancer.

24 Aug 2023

Researchers discover new biological mechanism to regenerate and repair myelin

A study led by Dr. Hyun Kyoung Lee, associate professor at Baylor College of Medicine and investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, has discovered a new biological mechanism to regenerate and repair myelin, a protective sheath that insulates neuronal fibers and plays a vital role in ensuring rapid and accurate neurotransmission.

24 Aug 2023

KAUST researchers refute challenges to targeted cancer therapy

Drugs that inhibit a key protein should offer new targeted cancer therapy for leukemia and breast cancer.

24 Aug 2023

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported Aug. 24 in the Journal of Clinical Investigation.

24 Aug 2023

Ketogenic diets, gut microbiota, and health effects

The evidence on ketogenic diets (KDs) from the past three decades.

24 Aug 2023

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

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24 Aug 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

Study shows that CD98hc can be targeted to deliver biotherapeutics in brain

Researchers engineered and characterized a blood-brain barrier transport vehicle targeting the CD98 heavy chain of heterodimeric amino acid transporters.

24 Aug 2023

Study finds examining retinal structure could provide markers for Parkinson disease

A new paper examined the retinal data from Parkinson disease patients in attempt to identify disease markers.

24 Aug 2023

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

23 Aug 2023

Protein C News and Research

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

Researchers discover new therapeutic approach for neuroblastoma

Semaglutide could be a game-changer for patients with HFpEF and obesity

UK Biobank Dementia Risk Score outperforms other widely used scores

Researchers discover how proteins regulate 'treadmilling' in cells

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

MFGM and milk protein may improve physical functioning of the elderly, study shows

Novavax's protein-based COVID vaccine induces broad functional immune response against XBB subvariants, data shows

Researchers develop new, modular strategy for T-cell-based immunotherapy

Midnolin protein plays key role in breaking down short-lived nuclear proteins

New research sheds light on role of KRAS mutations in pancreatic cancer

Researchers discover new biological mechanism to regenerate and repair myelin

KAUST researchers refute challenges to targeted cancer therapy

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Ketogenic diets, gut microbiota, and health effects

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Study shows that CD98hc can be targeted to deliver biotherapeutics in brain

Study finds examining retinal structure could provide markers for Parkinson disease

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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