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New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

Metformin, the most commonly used drug to treat type 2 diabetes, not only lowers blood sugar levels but has revealed to extend lifespan in C. Elegans -- an animal model that shares similar metabolic systems with humans and are often used to model human diseases.

23 Aug 2023

Naked mole rat gene boosts health and longevity in mice

In a groundbreaking endeavor, researchers at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan.

23 Aug 2023

New gene variant linked to Parkinson's disease found in people of African ancestry

A gene variant found almost exclusively in the genomes of people of African ancestry increases the risk of developing Parkinson's disease, according to an international study of nearly 198,000 participants with this genetic background.

23 Aug 2023

41% of people with post-viral syndrome had evidence of SARS-CoV-2 exposure

Millions of Americans were exposed to SARS-CoV-2, the virus that causes COVID-19, early in the pandemic but could not get diagnosed due to testing limitations.

23 Aug 2023

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

With around 90% of drugs failing to make it to market, the potential for improving efficiency within the drug development industry is clear. Drugs designed to combat cancers suffer similar rates of failure for many reasons.

23 Aug 2023

New kidney tissue model could help assess safety of immunotherapy drugs

A growing repertoire of cell and molecule-based immunotherapies is offering patients with indomitable cancers new hope by mobilizing their immune systems against tumor cells.

23 Aug 2023

Study explores the role of N6-methyladensoine methylation and COVID-19

A recent study summarized the recent advances in the role of N6-methyladenosine (m6A) methylation in COVID-19.

23 Aug 2023

Artificial intelligence and polyclonal antibody sequencing redefine the future of antibody discovery

In this interview, News-Medical had the opportunity to speak with Dr. Xiaobing Han, Principal Scientist for Antibody Discovery at Rapid Novor.

From Rapid Novor Inc 23 Aug 2023

Study explores lipid and metabolic alterations in HIV/TB co-infected patients

Researchers investigated the differential impact of HIV/tuberculosis co-infection on lipid and metabolic profiles.

23 Aug 2023

How does COVID-19 influence your gut microbiota?

Researchers analyzed the fecal microbiota composition in COVID-19 patients in comparison to non-COVID-19 controls.

23 Aug 2023

Current and future strategies for vaccinating against invasive pneumococcal disease

Researchers reviewed the immune mechanisms employed by existing vaccines for invasive pneumococcal disease.

23 Aug 2023

Scientists find way to 'press self-destruct button' in gastric cancer associated with Epstein-Barr Virus

Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.

22 Aug 2023

Gut-first theory of Parkinson's disease gains traction

Ask any neurologist: Parkinson's disease is a brain disorder. The conspicuous symptoms of Parkinson's disease - uncontrollable tremors, slowed down motions, and the feeling that one's feet are stuck to the ground - all stem from the loss of neurons in a region of the brain that helps control movement.

22 Aug 2023

Music can trigger cells to release insulin within minutes

Diabetes is a condition in which the body produces too little or no insulin. Diabetics thus depend on an external supply of this hormone via injection or pump.

22 Aug 2023

New insights into the pathogenic mechanisms of SLC29A3 disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

22 Aug 2023

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

The National Heart, Lung, and Blood Institute (NHLBI) recently awarded The Texas Heart Institute (THI) a two-year, $1.14 million grant to develop a novel, first-in-class drug to treat cardiovascular disease (CVD) as a significant improvement to current treatment regimens - specifically for adverse events arising from atherosclerosis.

22 Aug 2023

AI-powered protein score predicts major atherosclerotic cardiovascular disease events

In a large retrospective analysis using measurements of thousands of plasma proteins in primary and secondary event populations, scientists from deCODE genetics a subsidiary of Amgen and collaborators from USA, Denmark and Iceland, reported today in The Journal of the American Medical Association (JAMA) how they employed AI to develop a protein score to predict major atherosclerotic cardiovascular disease events (ASCVD).

22 Aug 2023

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

The prevalence of colorectal cancer in people under the age of 50 has risen in recent decades. One suspected reason: the increasing rate of obesity and high-fat diets.

22 Aug 2023

Genetically diverse mouse models offer new insights into Alzheimer's disease

A new study by Indiana University School of Medicine researchers uses more genetically diverse mouse models to study the accumulation and spread of abnormal tau protein deposits in the brain - a known sign of Alzheimer's disease and several other neurodegenerative diseases.

22 Aug 2023

Protein C News and Research

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

Naked mole rat gene boosts health and longevity in mice

New gene variant linked to Parkinson's disease found in people of African ancestry

41% of people with post-viral syndrome had evidence of SARS-CoV-2 exposure

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

New kidney tissue model could help assess safety of immunotherapy drugs

Study explores the role of N6-methyladensoine methylation and COVID-19

Artificial intelligence and polyclonal antibody sequencing redefine the future of antibody discovery

Study explores lipid and metabolic alterations in HIV/TB co-infected patients

How does COVID-19 influence your gut microbiota?

Current and future strategies for vaccinating against invasive pneumococcal disease

Scientists find way to 'press self-destruct button' in gastric cancer associated with Epstein-Barr Virus

Gut-first theory of Parkinson's disease gains traction

Music can trigger cells to release insulin within minutes

New insights into the pathogenic mechanisms of SLC29A3 disorders

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

AI-powered protein score predicts major atherosclerotic cardiovascular disease events

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

Genetically diverse mouse models offer new insights into Alzheimer's disease

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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