Therapy News and Research

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Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

Keck Medicine of USC expands to Las Vegas for transplant care

More than 660 Nevadans need an organ transplant, according to Nevada Organ Network, a federally designated organ procurement organization; but many currently struggle to access care because of limited transplant services available in Nevada.

26 Apr 2024

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Adding a pre-ketone supplement - a component of a high-fat, low-carb ketogenic diet - to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University of Notre Dame found.

26 Apr 2024

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

A team of clinician-scientists and scientists from the University of Nottingham (Malaysia campus), National Cancer Centre Singapore (NCCS), Cancer Research Malaysia, Nanyang Technological University, Singapore (NTU Singapore), University of Malaya, University of Cambridge, A*STAR's Genome Institute of Singapore (GIS) and other institutions, have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population.

26 Apr 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

Study suggests a common brain network exists between heart rate deceleration and depression

A new study by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests a common brain network exists between heart rate deceleration and depression.

26 Apr 2024

Study highlights oversight in childhood brain injury checks

Almost a quarter of US children with symptoms of a brain injury or concussion are not checked for the condition, with younger children particularly likely to be overlooked, a new national study finds.

26 Apr 2024

California is investing $500M in therapy apps for youth. Advocates fear it won’t pay off.

With little pomp, California launched two apps at the start of the year offering free behavioral health services to youths to help them cope with everything from living with anxiety to body acceptance.

26 Apr 2024

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer.

26 Apr 2024

Exploring the potential of ketogenic diets in managing epilepsy

The mechanisms of action, efficacy, and side effects of ketogenic diet (KD) variations in epileptic patients.

26 Apr 2024

How body shape influences colorectal cancer risk

Study reveals that specific body shape phenotypes, such as general obesity and central obesity, significantly increase the risk of colorectal cancer, suggesting distinct molecular pathways for different adiposity subtypes.

25 Apr 2024

Study: Antibiotic use in moderate COVID-19 linked to clinical deterioration

Antibiotic treatment of adults hospitalized with moderate COVID-19 is associated with clinical deterioration, despite the drugs being given to over 40% of patients, according to new research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April)

25 Apr 2024

Study finds rise in volumes and survival after hematopoietic cell transplants among racial/ethnic minorities

The volume of hematopoietic cell transplants rose among all racial/ethnic groups, but grew faster among African Americans and Hispanics compared with Non-Hispanic white individuals, mirroring changes in population growth rates.

25 Apr 2024

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Advancing medical treatment with causal machine learning

Machines can learn not only to make predictions, but also to handle causal relationships. An international research team shows how this could make therapies safer, more efficient, and more individualized.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Reduction of prenatal depression associated with higher full-term birth rates

The effect of lowering prenatal mother depression on gestational duration.

25 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Paclitaxel treatment found to directly promote HBV replication and transcription

Hepatitis B virus (HBV) reactivation is commonly observed in individuals with chronic HBV infection undergoing antineoplastic drug therapy.

24 Apr 2024

Therapy News and Research

Harnessing immune enhancement to combat drug-resistant tuberculosis

Keck Medicine of USC expands to Las Vegas for transplant care

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Study suggests a common brain network exists between heart rate deceleration and depression

Study highlights oversight in childhood brain injury checks

California is investing $500M in therapy apps for youth. Advocates fear it won’t pay off.

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

Exploring the potential of ketogenic diets in managing epilepsy

How body shape influences colorectal cancer risk

Study: Antibiotic use in moderate COVID-19 linked to clinical deterioration

Study finds rise in volumes and survival after hematopoietic cell transplants among racial/ethnic minorities

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Advancing medical treatment with causal machine learning

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Reduction of prenatal depression associated with higher full-term birth rates

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

Paclitaxel treatment found to directly promote HBV replication and transcription

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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