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Researchers identify alternative treatment for bacterial meningitis

With the increasing threat of antibiotic resistance, there is a growing need for new treatment strategies against life threatening bacterial infections.

10 Apr 2019

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

A new molecule -EPB-53-, could help fight type 2 diabetes and the non-alcoholic fatty liver disease, according to a new study led by the team of Manuel Vázquez-Carrera, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the University of Barcelona, and the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Center.

10 Apr 2019

Alcohol, Cannabis and Other Drugs: A Pharmacological Evaluation

Understanding the interactions between alcohol and cannabis can provide researchers, clinicians and other HCPs with important information on the severity of their side effects.

10 Apr 2019

Proton therapy shows excellent outcomes, minimal side effects in high-risk neuroblastoma patients

Researchers from Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania analyzed the largest cohort to date of pediatric patients with high-risk neuroblastoma treated with proton radiation therapy, finding both that proton therapy was effective at reducing tumors and demonstrated minimal toxicity to surrounding organs.

10 Apr 2019

Hepatitis C infections could be reduced by stepping up efforts to prevent transmission in people who inject drugs

Stepping up efforts to prevent transmission of hepatitis C among people who inject drugs, could reduce future infections by 43 per cent globally, according to a study by researchers at the University of Bristol published in the Lancet Gastroenterology and Hepatology today [Tuesday 9 April 2019].

10 Apr 2019

Prescribed medication reduces arrests, incarceration among people with opioid use disorder

When it comes to addressing the national opioid crisis, most of the research has focused on the physical health risks faced by people with opioid use disorder, such as overdose and infectious disease.

9 Apr 2019

TGen review associates a gene with hepatocellular carcinoma

Hepatocellular carcinoma is a long medical name for the most common form of liver cancer, a malignancy whose incidence has nearly doubled over the past decade, making it the fastest growing type of cancer in the U.S., and the third-leading cause of cancer-related death worldwide.

9 Apr 2019

Unexpected function of enzyme in sounding alarm about liver damage could lead to new treatments

On a normal day, the cells of a human liver do what they do best - making key blood proteins, clearing toxins from the blood and sending their remains down the digestive tract in a never-ending stream of bile.

9 Apr 2019

FDA approves two-drug complete regimen for previously untreated HIV-infected adults

The U.S. Food and Drug Administration today approved Dovato (dolutegravir and lamivudine), as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults with no antiretroviral treatment history and with no known or suspected substitutions associated with resistance to the individual components of Dovato.

9 Apr 2019

Advances in deep brain stimulation for Parkinson’s could lead to treatments for other disorders

A new paper published in Nature Reviews Neurology suggests that recent advances in deep brain stimulation for Parkinson disease could lead to treatments for conditions such as obsessive-compulsive disorder, Gilles de la Tourette syndrome and depression.

8 Apr 2019

Cellular protein could take on role of restriction factor for hepatitis B virus

Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not curative for infected individuals.

8 Apr 2019

New clinical trials to investigate combination immunotherapy for treating advanced cancers

City of Hope physician-scientists recently opened two clinical trials to investigate a combination of cytokines and immunotherapy that may be able to transform nearly-impossible-to-treat cancer into a disease that can be corralled into remission.

8 Apr 2019

Rising rates of liver cancer deaths largely confined to individuals with less education

A new study reveals that rising rates of liver cancer deaths in the United States have largely been confined to individuals who have received less education, especially among men.

8 Apr 2019

Researchers identify genetic mutations that can promote regeneration after liver damage

Researchers at the Children's Medical Center Research Institute at UT Southwestern have identified genetic mutations that accumulate in the adult liver that can promote regeneration in the context of chronic liver damage.

5 Apr 2019

Magnetic nanoparticles can 'heat up' tumor cells

Unfortunately, cancer isn't simply a single disease, and some types, like pancreas, brain or liver tumors, are still difficult to treat with chemotherapy, radiation therapy or surgery, leading to low survival rates for patients.

5 Apr 2019

FDA extends indication of metastatic breast cancer treatment to include male patients

The U.S. Food and Drug Administration today is extending the indication of Ibrance (palbociclib) capsules in combination with specific endocrine therapies for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in male patients.

5 Apr 2019

Study offers new hope for patients with decompensated cirrhosis

Decompensated cirrhosis is a chronic disease linked to numerous complications in its final stage. Professor Jonel Trebicka from Goethe University was involved in carrying out a pilot study demonstrating that the long-term administration of albumin in high doses stabilizes the circulatory function of these patients and protects them from sepsis.

4 Apr 2019

UB researchers develop new method to more accurately predict tumor growth rates

University at Buffalo researchers have developed a new method to more accurately predict tumor growth rates, a crucial statistic used to schedule screenings and set dosing regimens in cancer treatment.

4 Apr 2019

Study evaluates effects of unpaired 1 gene overexpression on lifespan in flies

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS announce the publication of a scientific article titled "Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster" in BMC Systems Biology - an open access journal publishing original peer-reviewed research articles in experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level.

4 Apr 2019

NIAID awards $22 million grant to develop antibody-based therapies against lethal viruses

The National Institute of Allergy and Infectious Diseases has awarded an international consortium led by Albert Einstein College of Medicine, part of Montefiore, a five-year, $22 million grant to develop antibody-based therapies against four highly lethal viruses for which there are no approved vaccines or treatments.

4 Apr 2019

Liver News and Research

Researchers identify alternative treatment for bacterial meningitis

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

Alcohol, Cannabis and Other Drugs: A Pharmacological Evaluation

Proton therapy shows excellent outcomes, minimal side effects in high-risk neuroblastoma patients

Hepatitis C infections could be reduced by stepping up efforts to prevent transmission in people who inject drugs

Prescribed medication reduces arrests, incarceration among people with opioid use disorder

TGen review associates a gene with hepatocellular carcinoma

Unexpected function of enzyme in sounding alarm about liver damage could lead to new treatments

FDA approves two-drug complete regimen for previously untreated HIV-infected adults

Advances in deep brain stimulation for Parkinson’s could lead to treatments for other disorders

Cellular protein could take on role of restriction factor for hepatitis B virus

New clinical trials to investigate combination immunotherapy for treating advanced cancers

Rising rates of liver cancer deaths largely confined to individuals with less education

Researchers identify genetic mutations that can promote regeneration after liver damage

Magnetic nanoparticles can 'heat up' tumor cells

FDA extends indication of metastatic breast cancer treatment to include male patients

Study offers new hope for patients with decompensated cirrhosis

UB researchers develop new method to more accurately predict tumor growth rates

Study evaluates effects of unpaired 1 gene overexpression on lifespan in flies

NIAID awards $22 million grant to develop antibody-based therapies against lethal viruses

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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