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How artificial intelligence is poised to reshape medicine

In a recent review published in the journal of Nature Medicine, researchers discussed the results of a two-year weekly effort to track and communicate significant developments in medical (artificial intelligence) AI. They included prospective studies as well as developments in medical image analysis that have narrowed the gap between research and implementation.

24 Jan 2022

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)."

24 Jan 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Broccoli compound triggers controlled cell death and recycling of cellular components in fission yeast

Broccoli may contain advantages beyond nutrition. A molecule found in broccoli, cabbage and more digests down into DIM, a compound with brighter benefits than the name implies, such as inducing cell death in breast, prostate and colon cancer.

24 Jan 2022

Optical imaging reveals how cancer cells hijack metabolic activity to fuel pancreatic tumor growth

Pancreatic cancer is a rare, yet elusive and deadly cancer, with a five-year survival rate of about 10%. If the cancer has metastasized, that rate lowers to 3%. And treatment options are extremely limited.

22 Jan 2022

Echinacea as a potential force against coronavirus infections

A new review identified clinical studies evaluating coronavirus infections in the context of Echinacea administration and assessed preventive and therapy advantages against COVID-19.

21 Jan 2022

Study sheds light on how melanoma primes nearby lymph nodes for tumor metastases

Melanoma cells release small extracellular packages containing the protein nerve growth factor receptor, which primes nearby lymph nodes for tumor metastases, according to a new study by Weill Cornell Medicine investigators.

21 Jan 2022

MD Anderson and Yingli Pharma announce strategic alliance to advance many oncology programs

The University of Texas MD Anderson Cancer Center and Yingli Pharma US, Inc. today announced a strategic alliance to advance several oncology programs from preclinical discovery through clinical development.

20 Jan 2022

Eikonoklastes completes a license to add novel gene therapy for treating neurodegenerative diseases

Eikonoklastes Therapeutics, a preclinical stage biopharmaceutical company, today announced it has completed a license with the University of California San Diego to add a novel gene therapy for the treatment of neurodegenerative diseases.

20 Jan 2022

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, according to a new study in mice from Washington University School of Medicine in St. Louis.

19 Jan 2022

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

Glioblastoma, an aggressive cancer in the brain or spinal cord, has proven stubbornly resistant to newer immunotherapies. And radiation and chemotherapy, the standard treatment for glioblastoma, result in fewer than 10% of patients surviving longer than five years after diagnosis.

19 Jan 2022

Exploring the interactions between multiple respiratory viruses

A recent report explores the dynamics of viral interference between various respiratory viruses in light of the ongoing COVID-19 pandemic.

19 Jan 2022

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus.

19 Jan 2022

Non-invasive, novel urinary miRNA biomarker panel for colorectal cancer diagnosis

Researchers set out to develop and validate urine biomarkers for diagnosing gastric cancer and colorectal cancer.

19 Jan 2022

Independent drug action responsible for greater clinical efficacy of combination cancer therapies

Independent drug action, not synergy nor additivity, accounted for the clinical efficacy of nearly all examined combination therapies involving immune checkpoint inhibitors in clinical trials, according to results from a retrospective analysis.

19 Jan 2022

Antibody combination produces a synergistic response in difficult-to-treat pediatric cancers

A combination of anti-cancer antibodies produced a powerfully synergistic response in two hard-to-treat pediatric cancers, according to a new study, in mice, led by researchers at the Stanford University School of Medicine.

19 Jan 2022

Addition of hormone therapy to radiotherapy treatments improves survival in prostate cancer patients

Prostate cancer is the leading cause of cancer in men worldwide, and radiotherapy is one of the common forms of treatment.

18 Jan 2022

MD Anderson and Eisbach Bio collaborate to develop precision oncology drugs

The University of Texas MD Anderson Cancer Center and Eisbach Bio GmbH today announced a strategic research collaboration to jointly discover and develop precision oncology drugs that target synthetic lethal engines key to tumor genome evolution.

18 Jan 2022

New genomic signature can spot aggressive tumor cells from primary, untreated prostate cancers

Many cases of early prostate cancer are dominated by cells that are slow-growing, often leading to a clinical decision to monitor for progression before initiating treatments that can have adverse side effects.

18 Jan 2022

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Chinese scientists recently reported the key role of histone acetylation-regulated long noncoding RNA termed as lysosome cell death regulator (LCDR) in tumor survival, providing a potential diagnostic and therapeutic target for lung cancer.

18 Jan 2022

Tumor News and Research

How artificial intelligence is poised to reshape medicine

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Broccoli compound triggers controlled cell death and recycling of cellular components in fission yeast

Optical imaging reveals how cancer cells hijack metabolic activity to fuel pancreatic tumor growth

Echinacea as a potential force against coronavirus infections

Study sheds light on how melanoma primes nearby lymph nodes for tumor metastases

MD Anderson and Yingli Pharma announce strategic alliance to advance many oncology programs

Eikonoklastes completes a license to add novel gene therapy for treating neurodegenerative diseases

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

Exploring the interactions between multiple respiratory viruses

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

Non-invasive, novel urinary miRNA biomarker panel for colorectal cancer diagnosis

Independent drug action responsible for greater clinical efficacy of combination cancer therapies

Antibody combination produces a synergistic response in difficult-to-treat pediatric cancers

Addition of hormone therapy to radiotherapy treatments improves survival in prostate cancer patients

MD Anderson and Eisbach Bio collaborate to develop precision oncology drugs

New genomic signature can spot aggressive tumor cells from primary, untreated prostate cancers

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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