Adenocarcinoma News and Research

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Adenocarcinoma is cancer that begins in cells that line certain internal organs and that have gland-like (secretory) properties.

Biomarker may help identify prostate cancer patients at increased risk of metastasis

For about 90 percent of men with prostate cancer, the cancer remains localized to the primary site, resulting in a five-year survival rate of almost 100 percent.

9 May 2019

Elderly survivors of breast, lung, and skin cancers face risk of brain metastasis later in life

Elderly survivors of breast cancer, lung cancer, and melanoma face risk of brain metastasis later in life, and may require extra surveillance in the years following initial cancer treatment.

3 May 2019

Deletion of ATDC gene prevents development of pancreatic cancer in mice

The action of a gene called ATDC is required for the development of pancreatic cancer, a new study finds.

2 May 2019

Non-smokers who develop lung cancer are hugely disadvantaged, says PHE

Patients who do not smoke are at an increased risk of lung cancer due to air pollution, warns PHE. These patients are often overlooked and diagnosed late, with poor outcomes.

26 Apr 2019

Cervical cancer subtype increasing in several subpopulations of women

A new study reports that a type of cervical cancer that is less amenable to Pap testing is increasing in several subpopulations of women, pointing to the growing importance of human papillomavirus (HPV) testing and vaccination.

17 Apr 2019

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. I

12 Apr 2019

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre, have published in Cancer Cell the results of a study that shows full regression of advanced pancreatic ductal adenocarcinoma upon combined inhibition of the epidermal growth factor receptor and c-RAF kinase.

12 Apr 2019

New clinical trials to investigate combination immunotherapy for treating advanced cancers

City of Hope physician-scientists recently opened two clinical trials to investigate a combination of cytokines and immunotherapy that may be able to transform nearly-impossible-to-treat cancer into a disease that can be corralled into remission.

8 Apr 2019

New study finds that screening could help prevent rare types of cervical cancer

Rare types of cervical cancer can be effectively prevented with screening, a comprehensive study of identified cases of rare cervical cancer over a ten-year period in Sweden concludes. The study was conducted by researchers at Karolinska Institutet and is published in The BMJ.

4 Apr 2019

Analysis of tumor microenvironment to improve effectiveness of preclinical trials

It was shown that co-culturing HeLa adenocarcinoma cells, peripheral blood mononuclear cells, and mesenchymal stromal cells results in changes in the proliferative activity of the peripheral blood mononuclear cells and mesenchymal stromal cell populations.

3 Apr 2019

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of Michigan Rogel Cancer Center found.

27 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

Machine learning model can achieve pathologist-level classification of lung cancer slides

Machine learning has improved dramatically in recent years and shown great promise in the field of medical image analysis.

4 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma, the most common esophageal malignancy in the United States, according to new research out of Case Western Reserve University School of Medicine.

28 Feb 2019

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

The proportion of early-stage drug trials tackling the biggest cancer killers has declined sharply since the early 1990s as less common tumor types receive increasing attention, according to new research to be presented during the International Congress on Targeted Anticancer Therapies 2019, taking place from today to 27 February in Paris, France.

25 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

Adenocarcinoma News and Research

Further Reading

Biomarker may help identify prostate cancer patients at increased risk of metastasis

Elderly survivors of breast, lung, and skin cancers face risk of brain metastasis later in life

Deletion of ATDC gene prevents development of pancreatic cancer in mice

Non-smokers who develop lung cancer are hugely disadvantaged, says PHE

Cervical cancer subtype increasing in several subpopulations of women

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

New clinical trials to investigate combination immunotherapy for treating advanced cancers

New study finds that screening could help prevent rare types of cervical cancer

Analysis of tumor microenvironment to improve effectiveness of preclinical trials

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

City of Hope exhibits current studies and data on cancer therapies at AACR

Machine learning model can achieve pathologist-level classification of lung cancer slides

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Newly discovered drug targets could pave way for esophageal cancer therapeutics

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

New study finds how high-fat diets fuel colorectal cancer growth

Study: Cancer stem-like cells are maintained by MTHFD2 mitochondrial metabolic enzyme

Analysis of cervical precancer shows decline in two strains of HPV

Index endoscopy results are crucial for assessment of Barrett's patients

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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