C Reactive Protein News and Research

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Characterization of circulating neutrophils from hospitalized COVID-19 patients

A new preprint deals with the characterization of neutrophil phenotypes in an attempt to provide biomarkers that can predict severe disease in patients hospitalized with COVID-19.

8 Oct 2021

Oral health linked to COVID-19 severity in patients with cardiac diseases

The correlation between poor oral health and COVID-19 severity, as well as the correlation between oral health and delayed recovery, demonstrates a potential need to consider oral health an additional risk factor for cardiac patients who may contract COVID-19.

7 Oct 2021

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

A recent study discusses the rate of changes in peripheral blood white cells in individuals who have recovered from SARS-CoV-2 infection.

3 Oct 2021

SARS-CoV-2 nucleocapsid antigen as a possible COVID-19 severity marker

French researchers used a highly sensitive and specific nucleocapsid-Ag assay to explore the relationship between N-Ag in urine during COVID-19 and the severity of the disease in hospitalized patients.

30 Sep 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

Altered characteristics of granulocytes in COVID-19 patients can be linked to disease severity

COVID-19 disease severity seems to be affected by the characteristics of white blood cells called granulocytes, which are part of the innate immune system.

23 Sep 2021

Study supports the implementation of Beckman Coulter’s MDW in emergency labs as initial test to detect sepsis

Beckman Coulter announced the results of a prospective study carried out across two European hospitals, which found that Monocyte Distribution Width, in combination with White Blood Cell Count with Differential, has the diagnostic accuracy to detect the risk of sepsis and severe infection upon patient presentation in A&E, particularly when assessed in patients with a lower likelihood of sepsis.

22 Sep 2021

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

The scientists assessed epidemiological data from March to December 2020 from the CDC to investigate the prevalence of COVID-19 disease among different age groups.

21 Sep 2021

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

An opinion article aims to provide evidence that SP could be the possible factor for initiating the cytokine storm during severe SARS-CoV-2 infection.

21 Sep 2021

Researchers identify prediction markers which can be used to define COVID-19 severity

An estimated 14−17% of hospitalized COVID-19 patients develop a severe form of the disease, requiring oxygen support and admission to the intensive care unit.

20 Sep 2021

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection typically affects children only mildly, multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS) is a serious but rare complication occurring after infection.

16 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

SARS-CoV-2 can cause sustained biochemical dysregulation that results in long-COVID

This state has come to be known as long-COVID, and in a paper recently uploaded to the preprint server medRxiv* by Simjanoska et al. (September 7th, 2021) the biochemical parameters of long-COVID patients with prior mild, moderate, or severe COVID-19 that resulted in hospitalization are tracked in detail, finding a characteristically dysregulated immune and inflammatory response in the most seriously ill.

15 Sep 2021

Researchers explore whether cocoa supplementation can reduce aging

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

Severe COVID-19 is associated with expansion of immature myeloid cells and inflammation

A team of scientists in Ireland recently identified certain immune markers that can predict the progression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to severe coronavirus disease 2019 (COVID-19). Early detection of these predictive markers can facilitate therapeutic decision-making prior to peak severity.

7 Sep 2021

C Reactive Protein News and Research

Characterization of circulating neutrophils from hospitalized COVID-19 patients

Oral health linked to COVID-19 severity in patients with cardiac diseases

Persistent leukocyte changes three months after mild SARS-CoV-2 infection

SARS-CoV-2 nucleocapsid antigen as a possible COVID-19 severity marker

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

Altered characteristics of granulocytes in COVID-19 patients can be linked to disease severity

Study supports the implementation of Beckman Coulter’s MDW in emergency labs as initial test to detect sepsis

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

Researchers identify prediction markers which can be used to define COVID-19 severity

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

SARS-CoV-2 can cause sustained biochemical dysregulation that results in long-COVID

Researchers explore whether cocoa supplementation can reduce aging

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

Severe COVID-19 is associated with expansion of immature myeloid cells and inflammation

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Does SARS-CoV-2 affect male fertility?

Drinking alcohol at a young age associated with accelerated arterial stiffening

Low glycemic diet results in important improvements for people with diabetes

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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