Cartilage News and Research

RSS

Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Cell membrane nanofragments can act as nucleation sites for mineralization during bone formation

The burst of cells forming cartilage is associated with mineralization during the early stages of bone formation, and nanofragments of the cell membranes can act as nucleation sites for amorphous calcium phosphate, as reported in two studies just published in Integrative Biology and ASC Biomaterials Science and Engineering.

14 Feb 2018

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic.

7 Feb 2018

Novel hip resurfacing implant may give higher quality of life, greater mobility to patients

Surgeons are treating patients with a new type of hip implant that could lead to better outcomes for younger, more active people requiring surgery.

7 Feb 2018

Discovery of molecular nets may lead to new treatment approach for heart failure

Local researchers have discovered that a group of molecules, called chondroitin sulfate, normally found only in connective tissues such as the cartilage, accumulates and causes inflammation in the hearts of patients with heart failure.

31 Jan 2018

Biotechnology startup receives FDA clearance for synthetic bone graft substitute

A biotechnology startup enabled by UC Davis, Molecular Matrix Inc., has received Food and Drug Administration clearance for a carbohydrate-based polymer that can help injured bones heal and regrow.

27 Jan 2018

TSRI scientists identify factors crucial to mesenchymal stem cell differentiation

Researchers at The Scripps Research Institute recently published a study in the journal Cell Death and Differentiation identifying factors crucial to mesenchymal stem cell differentiation, providing insight into how these cells should be studied for clinical purposes.

24 Jan 2018

Scientists take tissue-engineering approach to improve healing related to skeletal system

"Take a knee." "On bended knee." A "knee-slapper." "The bee's knees." The knee certainly carries a lot of weight in the English language, just as it does in the body. As the largest and one of the most complicated joints, the knee is also one of the most easily injured.

23 Jan 2018

Phase III clinical study of regenerative therapy for treating damaged cartilage has started

A group of researchers at Osaka University developed a synthetic tissue using synovium-derived mesenchymal stem cells (MSCs) for treating damaged cartilage, which had previously been incurable and had no effective therapies.

4 Jan 2018

Doctors use new procedure in patients with damaged hips to avoid replacement surgery

Doctors at The Ohio State University Wexner Medical Center are using a procedure called Subchondroplasty to give patients with damaged hips more treatment options and ultimately avoid replacement surgery.

18 Dec 2017

Harvard scientists discover hundreds of genetic switches that influence height

It's been understood for decades that a host of factors - everything from pre- and post-natal health, nutrition, and genetics - play a role in determining height, but efforts to untangle the complex web of factors that contribute to height have long been stymied.

6 Dec 2017

Losing weight via exercise alone may not protect your knees, study says

A new MRI study presented yesterday at the annual meeting of the Radiological Society of North America (RSNA) stated that obese people who lose a significant amount of weight can slow down the degeneration of their knee cartilage, but only through exercise and diet or only by diet.

29 Nov 2017

USC researchers propose rules for making ribs

Scientists from the USC Stem Cell lab of Francesca Mariani recently shared a recipe for ribs, and it doesn't even require barbecue sauce.

29 Nov 2017

Newcastle scientists develop new technique that revolutionizes cell culture

A technique which revolutionizes cell culture by allowing the continuous production and collection of cells, has been developed by scientists at Newcastle University.

28 Nov 2017

Immune system plays key role in amount of osteoarthritic pain and progression

The immune system plays a pivotal role in the amount of pain and disease progression experienced by patients with osteoarthritis (OA), McMaster University researchers have found.

27 Nov 2017

Preclinical study shows clear path toward effective treatment for rare bone disease

Researchers at Sanford Burnham Prebys Medical Discovery Institute have led a preclinical study demonstrating that the drug palovarotene suppresses the formation of bony tumors (osteochondromas) in models of multiple hereditary exostoses (MHE).

20 Nov 2017

New Kevlar-based hydrogel recreates the magic of natural cartilage

The unparalleled liquid strength of cartilage, which is about 80 percent water, withstands some of the toughest forces on our bodies.

16 Nov 2017

Orthocell earns CE Mark approval for CelGro collagen medical device

Regenerative medicine company Orthocell Limited is pleased to announce receipt of European regulatory approval (CE Mark) for its CelGro collagen medical device.

8 Nov 2017

Many patients with knee, hip and spine osteoarthritis use opioids to manage chronic pain

A large percentage of patients with end-stage knee, hip and spine osteoarthritis use opioids to manage their chronic pain, especially those who are younger or have symptoms of depression, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

CRFA better than steroid injection for managing pain from knee osteoarthritis

For patients with osteoarthritis of the knee, a minimally invasive procedure called cooled radiofrequency ablation provides better pain reduction and functional improvement compared to steroid injection of the knee, concludes a study in Regional Anesthesia & Pain Medicine, published by Wolters Kluwer.

2 Nov 2017

Stem cells do not participate directly in cartilage regeneration but serve to ‘animate’ the process

Stem cell therapy has great potential for curing cartilage damage. However, it has remained unclear whether stem cells are responsible for regeneration or whether they trigger the process.

31 Oct 2017