Hypoxia News and Research

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Hypoxia is a condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.

Researchers find a potential modulator in revascularization of pancreatic islets

The first cause of the loss of functionality in transplanted pancreatic islets is the low capacity to create new vessels to allow the arrival of nutrients in the cells.

20 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019

FAU scientists develop rapid, reliable method to continuously monitor sickle cell disease

Sickle cell disease is a hereditary disorder that affects red blood cells, distorting their natural disc shape into a crescent moon or "sickle" shape. Normal red blood cells move freely through small vessels throughout the body to deliver oxygen.

14 Jun 2019

New research identifies cellular adaptive mechanisms during hypoxic conditions

Circadian rhythms are 24 hour cycles that are guided by exposure to alternating periods of day and night. These cycles affect biological activities in a variety of living organisms which are attuned to the circadian clock.

12 Jun 2019

How pathogens are controlled under hypoxic conditions

Infected tissue has a low concentration of oxygen. The body's standard immune mechanisms, which rely on oxygen, can then only function to a limited extent.

24 May 2019

Study explores how exposure to potential triggers can increase risk of type 1 diabetes

A new study has investigated how exposure to certain triggers can increase the risk of type 1 diabetes.

22 May 2019

UA-led public health initiative increases survival rates of severe TBI victims

The implementation of a massive, statewide public health initiative led by University of Arizona researchers and involving 21,000 prehospital care patients has doubled the survival rate of severe traumatic brain injury victims and tripled the survival rate among those who were intubated.

8 May 2019

KAIST research team finds cause of sepsis-induced lung injury

A KAIST research team succeeded in visualizing pulmonary microcirculation and circulating cells in vivo with a custom-built 3D intravital lung microscopic imaging system.

7 May 2019

Low oxygen levels harm specific cells in the developing brain

Low oxygen levels are a well-known cause of brain injury in premature babies. But the mechanism by which low oxygen hurts the developing human brain has been unclear.

6 May 2019

PPDC announces seed grants to develop medical devices for children

The Pennsylvania Pediatric Medical Device Consortium has announced its latest round of seed grants to companies developing medical devices for children. The Consortium chose four companies from 11 finalists in a competition to receive seed grants of $50,000 each.

3 May 2019

Fetal heart rate monitoring can help health workers to identify at risk fetuses

Worldwide, there are over 3 million stillbirths and approximately 3 million newborn deaths each year, most in low-resource countries.

30 Apr 2019

Angiotensin receptor blockers could improve response to cancer immunotherapy

A research team led by investigators at Massachusetts General Hospital and the Massachusetts Institute of Technology has found that combining a specialized version of an antihypertension drug with immune checkpoint blockers could increase the effectiveness of cancer immunotherapies.

30 Apr 2019

Study examines if caffeine could prevent harmful effects of PGE1 treatment on breathing

Researchers from the Department of Pediatrics at Case Western Reserve University School of Medicine and University Hospitals Rainbow Babies and Children's Hospital presented results of a study that investigated whether there are any deleterious effects of prostaglandin E1 treatment on breathing and whether these effects would be prevented via pre-treatment with caffeine.

30 Apr 2019

Prior radioprotection via EGLN inhibitor improves survival in mouse model of pancreatic cancer

Administration of the EGLN inhibitor FG-4592 prior to ablative radiotherapy provided protection against fatal gastrointestinal bleeding and improved survival in a mouse model of unresectable pancreatic cancer.

30 Apr 2019

New review on relationship between COPD and Type 2 diabetes

Chronic obstructive pulmonary disease is characterized by a chronic airflow obstruction that is associated with severe global mortality and morbidity.

23 Apr 2019

Morning exercise may burn more calories

Exercising in the morning rather than in the evening may be more beneficial to health, as research shows that morning exercise burns more carbohydrates.

19 Apr 2019

Researchers explore whether time of day can affect the body's response to physical exertion

Two papers appearing April 18 in the journal Cell Metabolism confirm that the circadian clock is an important factor in how the body responds to physical exertion.

19 Apr 2019

Maternal smoking and pre-eclampsia may affect fertility of offspring

Low levels of oxygen in the womb - which can be caused by smoking or conditions such as pre-eclampsia - may cause problems with fertility later in life, a study carried out in rats suggests.

29 Mar 2019

Study describes new muscular disease caused by mutation in myoglobin gene

Researchers of the Bellvitge Biomedical Research Institute led by Dr. Montse Olivé have described in Nature Communications a new muscular disease caused by a mutation in the myoglobin gene.

28 Mar 2019

Study suggests new approach to ameliorating obesity-associated metabolic abnormalities

The search by scientists to find ways to combat obesity continues. Recently, investigators have been exploring whether they can engage the lymphatic system to help regulate obesity-induced inflammation of fat (adipose) tissue and restore systemic metabolic fitness.

14 Mar 2019

Hypoxia News and Research

Further Reading

Researchers find a potential modulator in revascularization of pancreatic islets

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

FAU scientists develop rapid, reliable method to continuously monitor sickle cell disease

New research identifies cellular adaptive mechanisms during hypoxic conditions

How pathogens are controlled under hypoxic conditions

Study explores how exposure to potential triggers can increase risk of type 1 diabetes

UA-led public health initiative increases survival rates of severe TBI victims

KAIST research team finds cause of sepsis-induced lung injury

Low oxygen levels harm specific cells in the developing brain

PPDC announces seed grants to develop medical devices for children

Fetal heart rate monitoring can help health workers to identify at risk fetuses

Angiotensin receptor blockers could improve response to cancer immunotherapy

Study examines if caffeine could prevent harmful effects of PGE1 treatment on breathing

Prior radioprotection via EGLN inhibitor improves survival in mouse model of pancreatic cancer

New review on relationship between COPD and Type 2 diabetes

Morning exercise may burn more calories

Researchers explore whether time of day can affect the body's response to physical exertion

Maternal smoking and pre-eclampsia may affect fertility of offspring

Study describes new muscular disease caused by mutation in myoglobin gene

Study suggests new approach to ameliorating obesity-associated metabolic abnormalities

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