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Updated screening protocols could improve early diagnosis of cystic fibrosis

All states should adopt updated screening protocols so more newborns with cystic fibrosis can be diagnosed in the first weeks of life, when interventions can have the greatest benefit, according to the Cystic Fibrosis Foundation guidelines published April 2 in the International Journal of Neonatal Screening.

3 Apr 2025

New drug strategy targets Staphylococcus aureus toxin to treat pneumonia

Pneumonia caused by the bacterium Staphylococcus aureus is one of the most dangerous infections that can occur in hospital.

2 Apr 2025

High-fat diet linked to increased breast cancer metastasis risk

Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread to other organs – metastasize –. But the causes of this association are still not well understood.

2 Apr 2025

Pandemic disruptions linked to lower TB diagnoses in prisons worldwide

A new study found that reported diagnoses for tuberculosis were consistently lower than expected throughout the pandemic, even though incarceration rates remained largely consistent and TB detection among the general population managed to reverse after an early-pandemic decline.

1 Apr 2025

New antibiotic-resistant superbug discovered in Malaysian hospital

A virulent strain of antibiotic-resistant 'superbug' that causes severe disease has been found circulating in a Malaysian hospital - posing significant challenges to global public health, a new study reveals.

1 Apr 2025

Novel ARPC1B mutation identified in a patient with recurrent eosinophilia

Immunodeficiency disorders linked to cytoskeleton defects are rare and complex, often presenting with diverse clinical features.

1 Apr 2025

Research challenges traditional oxygen practices in trauma care

When a critically injured patient is admitted to the hospital, how much supplemental oxygen should they receive? New research published this week in JAMA Network Open led by investigators at the University of Colorado School of Medicine suggests it's often less than the current standard.

31 Mar 2025

Fluid restriction does not improve health in heart failure patients

People with heart failure have long been advised to limit the amount of fluids they consume each day to help reduce congestion, or the buildup of fluid in the lungs and extremities, but that advice provides no benefit, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Study finds no benefit of early IABP use in cardiogenic shock patients

Compared with standard medical care, early use of a temporary intra-aortic balloon pump (IABP) to support heart function in patients who were critically ill with cardiogenic shock caused by heart failure did not improve 60-day survival or enable more patients to successfully transition to long-term treatment, according to featured clinical research presented at the American College of Cardiology's Annual Scientific Session (ACC.25) and simultaneously published in JACC

31 Mar 2025

Study finds 4F-PCC superior to frozen plasma in reducing bleeding after cardiac surgery

In patients experiencing excessive bleeding during cardiac surgery, a concentrated blood product containing proteins that help the blood clot was significantly more effective and caused fewer adverse effects than frozen plasma, the standard therapy, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

29 Mar 2025

Rivaroxaban shown to be a viable alternative to warfarin for left ventricular thrombus

At three months of follow-up, patients hospitalized for a serious heart attack who were treated with the oral blood thinner rivaroxaban for a blood clot in the left ventricle did as well as similar patients who received standard treatment with warfarin, an older blood-thinning drug.

29 Mar 2025

Owlstone Medical secures investment from Cystic Fibrosis Foundation

Owlstone Medical ("Owlstone"), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced that the Cystic Fibrosis Foundation has made an up to USD $2.3 million equity investment (circa £1.7 million) in Owlstone to develop a breath test for Pseudomonas aeruginosa (PA) detection in patients with cystic fibrosis (CF).

29 Mar 2025

Their physical therapy coverage ran out before they could walk again

Mari Villar was slammed by a car that jumped the curb, breaking her legs and collapsing a lung. Amy Paulo was in pain from a femur surgery that wasn't healing properly.

28 Mar 2025

Cabozantinib gains FDA approval for treating advanced neuroendocrine tumors

Cabozantinib, an oral tyrosine kinase inhibitor, has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of patients with previously treated advanced neuroendocrine tumors (NETs).

26 Mar 2025

New open-source tool identifies aging cells to help fight chronic diseases

For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer's disease and other chronic diseases.

25 Mar 2025

Blocking Piezo2 may offer a new therapeutic approach for pulmonary fibrotic diseases

Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting the expression or function of Piezo2, a receptor that senses mechanical forces in tissues including stress, strain, and stiffness.

25 Mar 2025