Medicinal Chemistry News and Research

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Researchers discover how PC7 protein affects certain types of cognitive performance

A team of Montr-al researchers at the IRCM led by Dr. Nabil G. Seidah, in collaboration with Dr. William C. Wetsel's team at Duke University in the United States, discovered that the protein PC7 plays a critical role in the brain by affecting certain types of cognitive performance such as anxiety, learning and emotional memory. Their results, recently published in the scientific journals Proceedings of the National Academy of Sciences (PNAS) and Nature, could have a significant impact on regulating behaviour related to anxiety disorders and trauma.

4 Dec 2013

IRCM researcher sheds light on inconsistencies between pharmacogenomic studies

A bioinformatics expert at the IRCM, Benjamin Haibe-Kains, recently published an article stressing the importance of standardizing drug screening studies in the prestigious scientific journal Nature. The study supports the need for further development and standardization to improve the reproducibility of drug screening studies, as they are important in identifying new therapeutic agents and their potential combinations with existing drugs.

3 Dec 2013

EMD Serono's TocopheRx to focus on development of oral FSH agonists for infertility treatment

EMD Serono, Inc., a subsidiary of Merck KGaA, Darmstadt, Germany, announced today the creation of TocopheRx, a Boston-based spin-off company resulting from the Entrepreneur Partnership Program launched by Merck Serono, the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, in April 2012.

3 Dec 2013

Researchers discover new genetic risk factor for schizophrenia, bipolar disorder

Investigators at The Feinstein Institute for Medical Research have discovered a new genetic risk factor for schizophrenia and bipolar disorder called NDST3. The findings are published online in Nature Communications.

20 Nov 2013

Sanofi uses QUOSA's literature management tools to automate adverse event monitoring

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced that Sanofi, one of the world's leading pharmaceutical organizations, has implemented QUOSA's literature management tools to automate adverse event monitoring.

22 Oct 2013

Thomson Reuters, Orion Bionetworks partner to further understanding of multiple sclerosis

The Intellectual Property & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, today announced a collaboration with Orion Bionetworks to further the understanding of multiple sclerosis and advance the development of new therapies by generating predictive models of patient stratification and drug targets.

22 Oct 2013

Thomson Reuters adds Cortellis Clinical Trials Intelligence for drug discovery and development

The Intellectual Property & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, today announced the addition of Clinical Trials Intelligence to the Thomson Reuters CortellisTM suite, the industry's most comprehensive information solution for drug discovery and development.

19 Oct 2013

IRCM researchers identify new proteins crucial for hearing

A team of researchers led by Dr. Michel Cayouette at the IRCM made an important discovery, published online yesterday by the scientific journal Developmental Cell, that could better explain some inherited forms of hearing loss in humans. The Montr-al scientists identified a group of proteins crucial for shaping the cellular organ responsible for detecting sounds.

16 Oct 2013

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

Investigators at The Feinstein Institute for Medical Research have discovered a protein in the human body that can trigger and mediate inflammation in patients suffering from hemorrhage and sepsis. The findings were published in the online version of Nature Medicine on October 6, 2013.

7 Oct 2013

Scientists identify chemical agents that block flu virus's ability to replicate itself in cell culture

A new way to attack flu viruses is taking shape in laboratories at Rutgers University, where scientists have identified chemical agents that block the virus's ability to replicate itself in cell culture.

4 Oct 2013

Ernest Mario School of Pharmacy, Robert Wood Johnson Medical School to launch dual-degree program

A dual-degree program combining a doctorate in pharmacy with a medical degree has been developed by Rutgers University's Robert Wood Johnson Medical School and Ernest Mario School of Pharmacy.

21 Sep 2013

UdeM's IRIC and Bristol-Myers Squibb identify small molecule drug candidate against novel target

Universit- de Montr-al and the Institute for Research in Immunology and Cancer - Commercialization of Research today announced that researchers from UdeM's Institute for Research in Immunology and Cancer and Bristol-Myers Squibb Company have jointly identified a small molecule drug candidate against a novel target.

20 Sep 2013

TSRI scientists find new way to boost effectiveness of anticancer drugs

Scientists at The Scripps Research Institute (TSRI) have found a way to make dramatic improvements to the cancer cell-killing power of vinblastine, one of the most successful chemotherapy drugs of the past few decades.

17 Sep 2013

Bayer, Broad On Five-Year Mission To Search For Novel Cancer Therapeutics

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10 Sep 2013

SYNthesis med chem opens new medicinal chemistry unit in Cambridge's Babraham Research Campus

SYNthesis med chem, the global contract research organisation providing synthetic and medicinal chemistry services, today announced that the company has opened a new facility at the Babraham Research Campus in Cambridge, UK.

10 Sep 2013

Researchers take detailed images of morphing structure of Parkinson’s protein

Researchers have taken detailed images and measurements of the morphing structure of a brain protein thought to play a role in Parkinson's disease, information that could aid the development of medications to treat the condition.

7 Sep 2013

Researchers explore seas and oceans to discover novel antibiotics and other medical compounds

The life that inhabits the world's oceans has almost infinite variety. It remains an untapped source of diversity. "The oceans can be deep or shallow, they can be more or less tidal, and they can include unique environments such as volcanic vents," says Brian McNeil ofStrathclyde University in Scotland, UK.

5 Sep 2013

Medicinal Chemistry News and Research

Researchers discover how PC7 protein affects certain types of cognitive performance

IRCM researcher sheds light on inconsistencies between pharmacogenomic studies

EMD Serono's TocopheRx to focus on development of oral FSH agonists for infertility treatment

Researchers discover new genetic risk factor for schizophrenia, bipolar disorder

Sanofi uses QUOSA's literature management tools to automate adverse event monitoring

Thomson Reuters, Orion Bionetworks partner to further understanding of multiple sclerosis

Thomson Reuters adds Cortellis Clinical Trials Intelligence for drug discovery and development

IRCM researchers identify new proteins crucial for hearing

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

Scientists identify chemical agents that block flu virus's ability to replicate itself in cell culture

Ernest Mario School of Pharmacy, Robert Wood Johnson Medical School to launch dual-degree program

UdeM's IRIC and Bristol-Myers Squibb identify small molecule drug candidate against novel target

TSRI scientists find new way to boost effectiveness of anticancer drugs

Bayer, Broad On Five-Year Mission To Search For Novel Cancer Therapeutics

SYNthesis med chem opens new medicinal chemistry unit in Cambridge's Babraham Research Campus

Researchers take detailed images of morphing structure of Parkinson’s protein

Researchers explore seas and oceans to discover novel antibiotics and other medical compounds

£13M partnership to accelerate cancer-focused drug discovery launched by Queen's and Almac Discovery

Unique computer technology opens up discovery of smarter drugs to treat illnesses

UAB study points to protein pathway that could lead to new treatments for diabetes

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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