Medicinal Chemistry News and Research

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Ernest Mario School of Pharmacy, Robert Wood Johnson Medical School to launch dual-degree program

A dual-degree program combining a doctorate in pharmacy with a medical degree has been developed by Rutgers University's Robert Wood Johnson Medical School and Ernest Mario School of Pharmacy.

21 Sep 2013

UdeM's IRIC and Bristol-Myers Squibb identify small molecule drug candidate against novel target

Universit- de Montr-al and the Institute for Research in Immunology and Cancer - Commercialization of Research today announced that researchers from UdeM's Institute for Research in Immunology and Cancer and Bristol-Myers Squibb Company have jointly identified a small molecule drug candidate against a novel target.

20 Sep 2013

TSRI scientists find new way to boost effectiveness of anticancer drugs

Scientists at The Scripps Research Institute (TSRI) have found a way to make dramatic improvements to the cancer cell-killing power of vinblastine, one of the most successful chemotherapy drugs of the past few decades.

17 Sep 2013

Bayer, Broad On Five-Year Mission To Search For Novel Cancer Therapeutics

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10 Sep 2013

SYNthesis med chem opens new medicinal chemistry unit in Cambridge's Babraham Research Campus

SYNthesis med chem, the global contract research organisation providing synthetic and medicinal chemistry services, today announced that the company has opened a new facility at the Babraham Research Campus in Cambridge, UK.

10 Sep 2013

Researchers take detailed images of morphing structure of Parkinson’s protein

Researchers have taken detailed images and measurements of the morphing structure of a brain protein thought to play a role in Parkinson's disease, information that could aid the development of medications to treat the condition.

7 Sep 2013

Researchers explore seas and oceans to discover novel antibiotics and other medical compounds

The life that inhabits the world's oceans has almost infinite variety. It remains an untapped source of diversity. "The oceans can be deep or shallow, they can be more or less tidal, and they can include unique environments such as volcanic vents," says Brian McNeil ofStrathclyde University in Scotland, UK.

5 Sep 2013

£13M partnership to accelerate cancer-focused drug discovery launched by Queen's and Almac Discovery

A new -13 million partnership to accelerate cancer-focused drug discovery in Northern Ireland has been launched by Enterprise Minister Arlene Foster MLA.

5 Sep 2013

Unique computer technology opens up discovery of smarter drugs to treat illnesses

A unique computer technology that opens up the discovery of smarter drugs to treat major illnesses including heart disease has been invented by University of Strathclyde scientists.

27 Aug 2013

UAB study points to protein pathway that could lead to new treatments for diabetes

The same protein tells beta cells in the pancreas to stop making insulin and then to self-destruct as diabetes worsens, according to a University of Alabama at Birmingham study published online today in the journal Nature Medicine.

27 Aug 2013

Scientists discover crucial role of nitric oxide in cellular signaling and health

Scientists at the University of Illinois at Chicago College of Pharmacy have discovered a new role for nitric oxide, a gas molecule crucial for cellular signaling and health.

26 Aug 2013

Combination of anti-nausea drug and turmeric spice target cancer cells

In a laboratory, preclinical study recently published by the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers combined structural features from anti-nausea drug thalidomide with common kitchen spice turmeric to create hybrid molecules that effectively kill multiple myeloma cells.

20 Aug 2013

Researchers suggest new key to switch off signaling pathways that lead to hypertension

A team of University of California, San Diego researchers has designed new compounds that mimic those naturally used by the body to regulate blood pressure. The most promising of them may literally be the key to controlling hypertension, switching off the signaling pathways that lead to the deadly condition.

23 Jul 2013

Ensemble Therapeutics announces initiation of drug discovery collaboration with Alexion subsidiary

Ensemble Therapeutics, a biotechnology company developing Ensemblins, a novel class of small molecule therapeutics with the potential to modulate targets typically addressed by biologics, today announced the initiation of a drug discovery collaboration with a subsidiary of Alexion Pharmaceuticals, Inc., the global biopharmaceutical company focused on developing and commercializing life-transforming therapies for patients with life-threatening, ultra-rare disorders.

18 Jul 2013

Human filariasis research: an interview with Professor Mark Taylor, Liverpool School of Tropical Medicine

Filariasis refers to a group of diseases caused by parasitic worms, which are transmitted by blood feeding insects. Two species infect the lymphatic and blood systems causing lymphatic filariasis, which in some people can lead to gross swelling of the limbs and 'elephantiasis'.

18 Jul 2013

Scientists set out to develop safer versions of acetaminophen

Efforts to develop a safer form of acetaminophen - the pain and fever-reducer that is one of the most widely used drugs - have led to discovery of substances that may have less potentially toxic effects on the liver. A report on the research appears in ACS Medicinal Chemistry Letters.

12 Jul 2013

New approach delivers RNA drugs to silence malfunctioning genes

Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which are used to inhibit gene expression. The drugs, in essence, mimic a natural process called RNA interference.

10 Jul 2013

First broad-spectrum drugs to combat human rhinoviruses

Scientists are reporting progress in the search for the first broad-spectrum drugs to combat human rhinoviruses (HRVs), which cause humanity's most common infectious diseases.

27 Jun 2013

TSRI scientists receive NIH grant to create new drug for chronic lymphocytic leukemia

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded more than $1.4 million from the National Cancer Institute of the National Institutes of Health to create a potential new drug to attack the malignant cells that cause chronic lymphocytic leukemia (CLL), which is the most common leukemia in the Western world.

20 Jun 2013

UIC's Center for Clinical and Translational Science selects six research projects for new pilot grants

The University of Illinois at Chicago's Center for Clinical and Translational Science has selected six research projects to receive pilot grants in 2013.

15 May 2013