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Light-activated SpyLigation can turn on proteins both inside and outside of living cells

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail.

18 Apr 2023

The Parkinson's Pandemic: from the importance of early diagnosis to digital solutions

News Medical spoke to Michele Hu, Consultant Neurologist at Oxford University Hospitals and Professor of Clinical Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, about prodromal Parkinson's and what the future looks like for this neurological disease.

11 Apr 2023

BU researcher receives $1.5 million NIH grant to purchase state-of-the-art cryo-EM

Esther Bullitt, PhD, associate professor of pharmacology, physiology & biophysics at Boston University Chobanian & Avedisian School of Medicine, was awarded $1.5 million from the National Institutes of Health that will go toward the purchase of a cryogenic electron microscope.

10 Apr 2023

Creation of embryo-like structures from monkey embryonic stem cells for the first time

Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study.

6 Apr 2023

Some bacteria cells get hangry too, study finds

Have you ever been so hungry that you become angry, otherwise known as "hangry?" New research by Adam Rosenthal, PhD, assistant professor in the Department of Microbiology and Immunology, has found that some bacteria cells get hangry too, releasing harmful toxins into our bodies and making us sick.

3 Apr 2023

Next-level technology for making time-released drugs could be a remedy for missed medications

Missing crucial doses of medicines and vaccines could become a thing of the past thanks to Rice University bioengineers' next-level technology for making time-released drugs.

3 Apr 2023

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

From CrestOptics 3 Apr 2023

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

Using a self-built inverted microscope complete with laser optical tweezers to capture DNA, Yale Cancer Center and University of California Davis researchers for the first time created a visualization of the full-length human BRCA2 protein at the single molecule level.

31 Mar 2023

People with a rare form of brain and spinal cord cancer have poor prognosis, research reports

A team of researchers from the Nagoya University Graduate School of Medicine has reported that patients with a rare form of brain and spinal cord cancer, localized isocitrate dehydrogenase wild-type (IDHwt) histologically diffuse astrocytoma, have a poor prognosis similar to the most malignant types of brain and spinal cord tumors.

31 Mar 2023

New microscopy method illuminates the mechanics of embryo development

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging some energy in the process.

30 Mar 2023

Pulsating blood vessels drive brain waste clearance during sleep

The word "brainwashing" usually triggers negative associations. But our brain health for sure depends on it. Scientists at the University of Oslo have recently made new and important discoveries about how and why this happens when we are sleeping.

30 Mar 2023

Renishaw introduces new functionality to its inVia™ confocal Raman microscope

Renishaw is pleased to introduce fluorescence lifetime imaging microscopy (FLIM) functionality to its inVia™ confocal Raman microscope.

From Renishaw plc - Additive Manufacturing for Healthcare Applications 28 Mar 2023

Cryo-EM provides structural insights into a specific protein involved in Hailey-Hailey disease

Hailey-Hailey disease is a rare, inherited condition characterized by patches of blisters appearing mainly in the skin folds of the arm pits, groin and under the breasts.

24 Mar 2023

Inhibition of cell wall formation arrests staphylococcal cell division

We still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary if we want to develop new antibiotics.

23 Mar 2023

Upgraded tumor model points the way toward more effective cancer therapies

Tumor cells won't show their true selves in a petri dish, isolated from other cells.

20 Mar 2023

Using convolutional neural network to automate the identification of chromatid cohesion defects

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion.

13 Mar 2023

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Diagnostic imaging offers physicians and scientists critical visual representations of internal body structures, greatly enhancing clinical analysis and medical intervention.

10 Mar 2023

Astrocytes play a key role in motor learning

From steering a car to swinging a tennis racket, we learn to execute all kinds of skilled movements during our lives.

10 Mar 2023

New community-based diagnostic tool is feasible and effective for diagnosing tuberculosis

A new, low-cost, scalable package for diagnosing tuberculosis (TB) onsite in resource-poor community settings is feasible and effective, according to a new trial.

10 Mar 2023

New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

Although electron microscopy can already reveal details as small as one nanometer, ongoing research seeks to break through barriers limiting image quality and reducing the optical dose on the samples. Aberration is a common problem in electron microscopy that can reduce the resolution and quality of the images produced.

3 Mar 2023

Microscope News and Research

Light-activated SpyLigation can turn on proteins both inside and outside of living cells

The Parkinson's Pandemic: from the importance of early diagnosis to digital solutions

BU researcher receives $1.5 million NIH grant to purchase state-of-the-art cryo-EM

Creation of embryo-like structures from monkey embryonic stem cells for the first time

Some bacteria cells get hangry too, study finds

Next-level technology for making time-released drugs could be a remedy for missed medications

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

People with a rare form of brain and spinal cord cancer have poor prognosis, research reports

New microscopy method illuminates the mechanics of embryo development

Pulsating blood vessels drive brain waste clearance during sleep

Renishaw introduces new functionality to its inVia™ confocal Raman microscope

Cryo-EM provides structural insights into a specific protein involved in Hailey-Hailey disease

Inhibition of cell wall formation arrests staphylococcal cell division

Upgraded tumor model points the way toward more effective cancer therapies

Using convolutional neural network to automate the identification of chromatid cohesion defects

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Astrocytes play a key role in motor learning

New community-based diagnostic tool is feasible and effective for diagnosing tuberculosis

New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

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