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New imaging protocol enhances visualization of rare bone marrow cells

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to accurately identify rare LepR+ stromal cells.

21 Jan 2025

Breakthrough study maps critical structure of Nipah virus polymerase

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999.

20 Jan 2025

Exploring the role of confocal-based high-content imaging in advancing core facilities

In this interview, NewsMedical speaks with Esther Kieserman and Arvonn Tully from Yokogawa Life Science about how confocal-based high-content imaging is advancing core facility research and improving data reliability.

From Yokogawa Life Science 20 Jan 2025

Scientists reveal Homo erectus mastered desert survival one million years ago

Researchers discovered that Homo erectus adapted to hyperarid conditions in Tanzania one million years ago, challenging previous beliefs about early human ecological limitations.

19 Jan 2025

New discovery in HIV vaccine response reveals surprising antibody behavior

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.

17 Jan 2025

Aurox expands activity into North America

From Aurox Ltd 15 Jan 2025

Plant chemical discovered to prevent biofilm formation

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

10 Jan 2025

Biglycan and decorin play crucial roles in bone health

Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin.

10 Jan 2025

Breakthrough microscopy technique reveals how antibodies target cancer cells

In blood cancers such as chronic lymphocytic leukaemia, B cells of the immune system multiply uncontrollably.

10 Jan 2025

Aircraft noise pollution harms arteries, but heart drugs show promise in animal model research

Alpha- and beta-blockers reduce oxidative stress and inflammation caused by aircraft noise but fail to prevent hypertension, highlighting their potential to protect vascular health in noise-exposed individuals.

9 Jan 2025

Unraveling the push-pull mechanism of neuron migration

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

9 Jan 2025

Innovative AI approach enhances imaging in thick biological samples

Depth degradation is a problem biologists know all too well: The deeper you look into a sample, the fuzzier the image becomes.

7 Jan 2025

Specialized bone marrow niches reveal secrets of immune tolerance

Researchers have uncovered a hierarchical structure of immune-privileged stem cells in bone marrow niches, revealing their regenerative potential and therapeutic relevance.

2 Jan 2025

Advancing Raman microscopy for high-resolution imaging of biological samples

Understanding the behavior of the molecules and cells that make up our bodies is critical for the advancement of medicine.

30 Dec 2024

Complex interactions between nucleic acid sensors and enzymes in immune cells explained

Adenosine deaminase 2 (ADA2) has been identified as a regulator of toll-like receptor 9 (TLR9) activation in response to nucleic acids, according to a recent study.

26 Dec 2024

The "Goldilocks" zone: A key to cellular adaptability and resilience

In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as polyphosphate (polyP), and two basic building blocks of life: DNA and the element magnesium.

24 Dec 2024

Researchers identify key mechanism linking brain stress to Alzheimer's disease

Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD).

23 Dec 2024

Microglial cells may hold key to Alzheimer's plaque removal

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and releasing digestive enzymes into the space, according to a preclinical study by Weill Cornell Medicine investigators.

23 Dec 2024

Dextromethorphan found to have potential in treating lung fibrosis

A common over-the-counter ingredient in many cough syrups may have a greater purpose for people suffering from lung fibrosis that is related to any number of serious health conditions.

22 Dec 2024

Amira Software Version 2024.2: Enhancing ultrastructure analysis

Amira Software Version 2024.2 offers groundbreaking AI enhancements and advanced tools, transforming cellular ultrastructure analysis and research workflows.

From Thermo Fisher Scientific - Software 20 Dec 2024