Neurodegenerative Diseases News and Research

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Scientists uncover "superspreader" fibrils driving Alzheimer's Disease

The treatment of dementia disorders such as Alzheimer's is still one of the greatest challenges facing modern medicine. In the course of neurodegenerative diseases, certain proteins such as the amyloid β protein accumulate in the brain. They are suspected of being linked to the development of the disease, which is why they are considered a promising target for therapeutic approaches.

28 Oct 2024

Semaglutide may reduce Alzheimer's risk in diabetics

Researchers use real-world data in the United States to evaluate the protective role of semaglutide against Alzherimer’s disease.

25 Oct 2024

Study links gut bacteria infection to Alzheimer's disease progression

A groundbreaking study by researchers at Florida State University's Gut Biome Lab has revealed a potential link between an infection caused by gut bacteria and the progression of Alzheimer's disease.

24 Oct 2024

Research uncovers new insights into neuronal aging and rejuvenation

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal aging — inevitable with the passing of time — is particularly accelerated and becomes a risk factor in neurodegenerative pathologies such as Alzheimer's disease.

24 Oct 2024

Study reveals hormone receptors' role in brain health and neuroprotection

In a comprehensive review published in the October 2024 issue of Genomic Psychiatry, researchers have unveiled crucial insights into how two types of hormone receptors collaborate to maintain brain health and potentially prevent neurodegenerative diseases.

24 Oct 2024

Brain aging may hold the key to predicting Alzheimer’s risk

Research reveals advanced brain aging in older adults correlates with cognitive decline and Alzheimer's risk, highlighting the need for early intervention.

24 Oct 2024

Human midbrain organoids: A promising tool in the fight against Parkinson's disease

Advancements in organoid technology are crucial for Parkinson's disease research, providing human-relevant models for studying disease and testing therapies.

23 Oct 2024

New drug shows promise for motor neurone disease treatment

A pioneering study published in the International Journal of Molecular Sciences by researchers at Durham University has revealed promising results for a new treatment targeting motor neurone disease (MND).

22 Oct 2024

AI model analyzes retinal images to detect early Alzheimer’s disease and cognitive decline

Researchers developed an AI-based deep learning model that uses retinal images to detect early-stage Alzheimer's disease and mild cognitive impairment with high accuracy, offering a noninvasive, cost-effective screening tool.

22 Oct 2024

New study reveals molecular mechanism in Alzheimer's disease

A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new molecular mechanism that affects RNA processing and alters the process of protein synthesis in the brains of Alzheimer's patients.

18 Oct 2024

New protein found to protect cells from age-related decline

McMaster University researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall.

18 Oct 2024

Study reveals how Alzheimer's may cause brain damage in two distinct phases

Alzheimer's disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

15 Oct 2024

Emory University researchers shift focus to neuroinflammation in Alzheimer's treatment

For decades, Alzheimer's research has focused on examining amyloid plaques in the brain and prescribing antibody therapeutics that remove the plaques to slow cognitive decline in patients.

15 Oct 2024

Study explores impact of active navigation and immersive environments on episodic memory

Just like a time machine, episodic memory enables us to travel to the past in our minds and relive personal experiences with full clarity, as if we were going through them all over again.

15 Oct 2024

A novel approach to understanding protein compartmentalization

In physics, a system composed of two substances can be modeled in accordance with classical mixture theory, which considers the fraction corresponding to each constituent and the interactions among constituents. Examples include the coexistence of high- and low-density phases in supercooled water and the coexistence of metal puddles in an insulating matrix in the Mott metal-insulator transition.

14 Oct 2024

Boost your heart, save your brain: How better heart health fights dementia

Research highlights the strong connection between heart and brain health, showing that improving cardiovascular health can help prevent cognitive decline and dementia. It underscores the shared biological mechanisms that link cardiac diseases to neurological impairment.

13 Oct 2024

New insights on protein degraders open doors to treatment for 'undruggable' diseases

Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called 'protein degraders' which can be deployed to combat what have previously been regarded as 'undruggable' diseases, including cancers and neurodegenerative diseases.

12 Oct 2024

Three common cardiovascular diseases linked to cognitive impairment and dementia risk

Three common cardiovascular diseases in adults - heart failure, atrial fibrillation and coronary heart disease - are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association published today in the Association's journal, Stroke.

10 Oct 2024

The role of geroscience in understanding Alzheimer’s Disease

For more than 30 years, researchers have identified and quantified genetic and lifestyle factors for Alzheimer's Disease (AD) and other dementias. Despite extensive research, the fundamental mechanisms behind these neurodegenerative diseases are still not fully understood, and effective management of AD is taking longer than expected.

10 Oct 2024

Pitt researchers validate comprehensive blood test for Alzheimer's biomarkers

University of Pittsburgh scientists independently validated a new blood test platform that can simultaneously measure more than a hundred biomarkers of Alzheimer's disease.

9 Oct 2024