Nitric Oxide News and Research

RSS

Natural compound coumarins exhibit anti-inflammatory as well as anticoagulant activities

New methods for the laboratory-scale synthesis of coumarin-based drugs were developed in a recent study completed at the University of Eastern Finland. In his doctoral thesis, Lic. Phil. Juri Timonen also developed new analytical methods for the fast identification of natural and non-natural coumarins.

26 Nov 2013

Japanese health authorities approve Aerocrine's NIOX MINO for assessing airway inflammation

Aerocrine AB announces today that Japanese health authorities have approved the use of its FeNO-measuring device NIOX MINO as a tool for assessing patients with airway inflammation such as asthma.

25 Nov 2013

Findings raise prospects for new therapies to protect heart from progressive disease

Some of the most commonly prescribed drugs for the treatment of heart failure are beta-blockers and nitrates, which help to relax blood vessels and decrease the heart's workload. The drugs were thought to produce those effects through distinct molecular pathways, but according to a new study led by scientists at Temple University School of Medicine, both types of drugs may help the failing heart by counteracting the effects of an enzyme known as GRK2.

8 Nov 2013

Brain & Behavior Research Foundation announces recipients of NARSAD Investigator Grants

The Brain & Behavior Research Foundation (formerly known as NARSAD, the National Alliance for Research on Schizophrenia and Depression), under the direction of Dr. Jeffrey Borenstein, President & CEO, has announced the latest recipients of its NARSAD Distinguished Investigator Grants.

8 Nov 2013

Weight loss reduces pediatric exercise-induced bronchoconstriction

A study has found that weight loss in overweight and obese children with exercise-induced bronchoconstriction leads to a significant reduction in symptom severity and improved quality of life.

5 Nov 2013

New clinical trial shows increased asthma control with FeNO-guided anti-inflammatory treatment

A new randomised clinical trial shows lower incidence of asthma exacerbations and increased asthma control with Fractional exhaled Nitric Oxide (FeNO)-guided anti-inflammatory treatment.

11 Oct 2013

Study shows nitric oxide can promote and inhibit lateral root formation

The structure and plasticity of root systems play an important role in determining the growth and yield of crop plants, and understanding how environmental and biological factors affect root structure is of key importance for plant scientists-particularly agricultural scientists.

9 Oct 2013

Bayer HealthCare receives FDA approval for Adempas tablets

Bayer HealthCare announced today that the United States Food and Drug Administration has approved Adempas (riociguat) tablets for: (i) the treatment of adults with persistent/recurrent chronic thromboembolic pulmonary hypertension (WHO Group 4) after surgical treatment or inoperable CTEPH to improve exercise capacity and WHO functional class; and (ii) the treatment of adults with pulmonary arterial hypertension (WHO Group 1) to improve exercise capacity, improve WHO functional class and delay clinical worsening.

9 Oct 2013

FENO and B-Eos complement each other as asthma biomarkers

Research indicates that fraction of exhaled nitric oxide and blood eosinophil count values can independently predict asthma diagnosis and attacks.

8 Oct 2013

Researchers develop C6 compound that prevents abnormalities linked with priapism in mice

It's not the little blue pill famous for helping men get big results, but for those who need it, the outcome might be even more significant. A new research report published online in The FASEB Journal, offers hope to men who experience priapism. This condition, which is often seen in men with sickle cell disease, causes erections lasting so long that they cause permanent damage to the penis.

1 Oct 2013

Arginine therapy may be safe treatment for patients with sickle cell disease

Arginine therapy may be a safe and inexpensive treatment for acute pain episodes in patients with sickle cell disease, according to results of a recent clinical study. The study was the first randomized placebo-controlled study to demonstrate benefits of arginine therapy in children with sickle cell disease hospitalized for severe pain.

17 Sep 2013

Research: Treatment with antioxidants may help reduce behavioral issues linked to NF1

New research in mouse models suggests that treatment with antioxidants may help reduce behavioral issues linked to the genetic nervous system disorder Neurofibromatosis 1 (NF1) and an associated condition called Costello syndrome.

12 Sep 2013

People with severe asthma are less likely to respond to treatment

Barcelona, Spain: People with severe asthma, who are often described as 'steroid-dependent', are actually less likely to respond to the treatment they depend on, when compared to people with mild asthma.

10 Sep 2013

Northumbria University psychologist to introduce diners to the science behind food and drink

Diners will discover how the food on their plate can impact their brain function at a special dining experience during the British Science Festival in Newcastle.

6 Sep 2013

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

This rare genetic condition can theoretically affect patients at any age but symptoms are more often observed in childhood and even uncommonly during the first days of life.

2 Sep 2013

Combination of music and exercise training improves endothelial function in CAD patients

Professor Deljanin Ilic said: "In the setting of cardiovascular risk factors and cardiovascular disease the endothelium loses its normal function.1 Since endothelium derived nitric oxide is necessary to maintain an adequate vascular response, correction of endothelial dysfunction has become a goal of therapy."

2 Sep 2013

BARDA Awards Novan $7.8M To Develop Thermal Burns Treatment

...

26 Aug 2013

Scientists discover crucial role of nitric oxide in cellular signaling and health

Scientists at the University of Illinois at Chicago College of Pharmacy have discovered a new role for nitric oxide, a gas molecule crucial for cellular signaling and health.

26 Aug 2013

UofL's Diabetes and Obesity Center receives $11.25M COBRE grant from NIH

A center created with a five-year National Institutes of Health grant at the University of Louisville in 2008 has won its second five-year grant.

14 Aug 2013

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

NOXXON Pharma today announced the successful completion of patient recruitment of its NOX-E36 Phase IIa clinical trial for the treatment of diabetic nephropathy. NOX-E36 is a Spiegelmer® that binds and neutralizes CCL2/MCP-1 (C-C Chemokine Ligand / Monocyte Chemoattractant Protein-1), a pro-inflammatory chemokine that plays an important role in the progression of diabetic nephropathy, the most common single cause of chronic kidney failure and end-stage renal disease.

25 Jul 2013