Tumor Necrosis Factor News and Research

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Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers studied the immune responses in Syrian hamsters re-infected with SARS-CoV-2 Delta and B.1 variants three months after the primary infection.

17 Mar 2022

Good glycemic control in SARS-CoV-2 vaccinated type 2 diabetic patients reduces risk of breakthrough infection

Adequate glycemic control during the year after being vaccinated against the SARS-CoV-2 improves the relative immunological response.

15 Mar 2022

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

Researchers evaluated the effectiveness of isotretinoin (13-cis retinoic acid) in improving COVID-19 outcomes.

14 Mar 2022

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Researchers analyze the available scientific evidence supporting vitamin D as a neuroprotective agent against the neurological sequelae of COVID-19.

14 Mar 2022

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

A new study used glycoprotein profiling technology platform that couples high-resolution LC-MS for glycoprotein analysis in regards to COVID-19.

9 Mar 2022

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

In a recent study posted to the bioRxiv* preprint server, researchers presented the intragenomic rearrangements of β-coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

9 Mar 2022

Study explores differentially expressed immune genes for COVID-19 patient stratification

In a new study, researchers determined the transcriptional signatures associated with the severity of COVID-19.

7 Mar 2022

Current progress in SARS-CoV-2 vaccine candidates

In a new study, researchers illustrated the current progress and obstacles in COVID-19 vaccine development.

7 Mar 2022

Study explores COVID-19 vaccine effectiveness in ankylosing spondylitis patients

Researchers estimated the immunogenicity of SARS-CoV-2 vaccination in a Belgian cohort of patients with ankylosing spondylitis.

7 Mar 2022

CD4 T-cell immunity active six months into COVID-19 convalescence

A new paper explores the presence of CD4 T-cell-mediated adaptive immunity against SARS-CoV-2 in late convalescence.

6 Mar 2022

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

An new study reports that a third dose of the Pfizer BNT162b2 vaccine produces high levels of anti-spike IgG antibodies in kidney transplant recipients.

6 Mar 2022

Potential molecular and clinical biomarkers of COVID-19 severity

Researchers have reviewed the currently published data examining the potential molecular and clinical biomarkers of COVID-19 severity.

4 Mar 2022

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

In a new study, researchers used deep transcriptome analysis to examine the coding and non-coding transcriptional landscape of lung cells infected with SARS-CoV-2.

1 Mar 2022

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Researchers characterized humoral and SARS-CoV-2 S-specific T cell responses in IBD patients who received two-dose mRNA-based COVID-19 vaccination series.

25 Feb 2022

Cell-mediated immune response among inflammatory bowel disease patients after mRNA COVID-19 vaccination

Researchers evaluated CMIR in IBD patients following immunization with two doses of COVID-19 vaccine.

25 Feb 2022

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

Researchers examined the detailed mechanisms of ‘cytokine storm’ that induces ARDS, often resulting in the death of severely ill COVID-19 patients.

21 Feb 2022

Study identifies a protein complex critical for regulating apoptosis and necroptosis

Cell death plays an important role in normal human development and health but requires tightly orchestrated balance to avert disease. Too much can trigger a massive inflammatory immune response that damages tissues and organs. Not enough can interfere with the body's ability to fight infection or lead to cancer.

18 Feb 2022

Tumor Necrosis Factor News and Research

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Good glycemic control in SARS-CoV-2 vaccinated type 2 diabetic patients reduces risk of breakthrough infection

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

Study explores differentially expressed immune genes for COVID-19 patient stratification

Current progress in SARS-CoV-2 vaccine candidates

Study explores COVID-19 vaccine effectiveness in ankylosing spondylitis patients

CD4 T-cell immunity active six months into COVID-19 convalescence

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

Potential molecular and clinical biomarkers of COVID-19 severity

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Cell-mediated immune response among inflammatory bowel disease patients after mRNA COVID-19 vaccination

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

Study identifies a protein complex critical for regulating apoptosis and necroptosis

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Changes in the brain cortex of COVID-19 patients associated with inflammatory biomarkers

Frequency and function of SARS-CoV-2-specific T cells in individuals with pulmonary PASC

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