Molecule News and Research

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Sanofi exercises option to advance innovative Bispecific Small Molecule project

Exscientia, the world-leading Artificial Intelligence (AI)-driven drug discovery company, today announced that Sanofi has exercised its option to progress an innovative Bispecific Small molecule project it discovered as part of its new modality collaboration.

From Sanofi 6 Aug 2019

Drug used to treat alcohol use disorder reduces craving in heavy drinkers

Researchers at Yale University have identified how naltrexone, a medication used to treat alcohol use disorder, reduces craving and consumption in heavy drinkers.

6 Aug 2019

New nanovaccine for deadly skin cancer

Tel Aviv scientists have published their version of a vaccine against the deadly skin cancer malignant melanoma, which arises from the pigment producing cells of the skin. This is the most feared form of skin cancer, with a high tendency to metastasize to distant parts of the body, including the brain.

6 Aug 2019

Scientists from Vilnius develop cost-effective and faster DNA testing method

DNA or genetic testing is a medical test that identifies changes in chromosomes, genes, or proteins to determine a genetic condition or eliminate the chance of the formation or passing on of a gene-based disorder amongst humans and animals.

6 Aug 2019

New research explains why some cancers don't respond to immunotherapy

New research has uncovered a mechanism thought to explain why some cancers don't respond to a widely used form of immunotherapy called "checkpoint inhibitors" or anti-PD-1.

6 Aug 2019

Sheffield academic receives funding to protect brain cells affected by Parkinson's

A Sheffield academic has been awarded £100,000 of funding by the Virtual Biotech Programme - the drug development arm of charity Parkinson's UK - to develop a new treatment that could protect brain cells affected by Parkinson's disease, potentially slowing, or stopping its progression for the first time.

6 Aug 2019

Rare immune cells may serve as 'periscopes' to monitor the body's immune status, study finds

A rare, short-lived population of immune cells in the bloodstream may serve as 'periscopes' to monitor immune status via lymph nodes deep inside the body, according to researchers in the Perelman School of Medicine at the University of Pennsylvania.

2 Aug 2019

Super-resolution microscopy helps unravel elusive causes of dementia

University of Queensland researchers have used super-resolution microscopy to observe key molecules at work inside living brain cells, further unraveling the puzzle of memory formation and the elusive causes of dementia.

2 Aug 2019

Study: Low level of exposure to traffic related PM10 can be harmful

Air pollution is made up of both gaseous and particulate matter. Each year almost two million people die as a direct result of air pollution with many more experiencing impaired lung function, developing lung diseases such as asthma and chronic obstructive pulmonary disease.

2 Aug 2019

Prion disease in mice treated successfully with antisense oligonucleotides

Prion proteins are known to cause scrapie – a neurodegenerative condition. It is capable of debilitating damage to the nervous system. Researchers have successfully devised a treatment for this condition which prolonged the lives of the lab mice infected with the prions.

1 Aug 2019

Simple, accurate, and fast: the new "sniff-cam" disease detector

It’s not just about garlic on the breath any more; your breath could now help reveal a variety of diseases. The science behind it is that the human body excretes a number of volatile compounds through the breath, and the type and proportion of these vary with the kind of disease.

1 Aug 2019

Selective antibiotics could make precision treatment possible

With multi-resistant germs becoming more and more of a threat, we are in need of new antibiotics now more than ever.

31 Jul 2019

Harnessing anti-inflammatory function of macrophages holds great potential for treating diseases

Researchers at the University of Illinois at Chicago have identified a molecular switch that causes immune cells called macrophages to clean up cellular debris caused by infections instead of contributing to inflammation and tissue injury.

31 Jul 2019

Understanding creation of antibiotic scaffolds could drive new class of antibiotics

Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining.

31 Jul 2019

Propranolol's target in treating rare vascular syndrome and hemangioma discovered

The discovery of a new target for the blood-pressure medication propranolol may lead to the development of new and safer therapies for vascular diseases, according to new findings published in eLife.

31 Jul 2019

NemaMetrix raises $5 million USD funding to expand its Precisome platform

NemaMetrix, an Oregon-based company that provides phenotyping and functional analysis using C. elegans nematodes, today announced it has closed a $5 million USD funding round to expand its Precisome platform: a tool for in vivo testing for early drug discovery, agribio, and precision medicine.

From InVivo Biosystems 30 Jul 2019

First ever American gene-editing treatment using CRISPR for genetic disease

In a pathbreaking experiment, a 34-year-old mother of four from Mississippi is in the limelight for volunteering to be the subject of CRISPR-mediated gene editing in the hope of achieving a cure for the painful sickle cell anemia with which she has suffered all her life.

30 Jul 2019

Researchers discover SIGN-R1 molecule that recognizes multiple variants of influenza

A team of researchers from the Institute for Research in Biomedicine (IRB, affiliated to USI Università della Svizzera italiana, Switzerland) have discovered and identified a molecule - SIGN-R1 - capable of recognizing the multiple variants of influenza and consequently 'directing' the immune response in individuals affected by the disease.

30 Jul 2019

Combination therapy could be a promising treatment for late-stage acute lymphoblastic leukemia

Acute lymphoblastic leukemia accounts for one in five adult leukemias, and is the most common pediatric cancer in the United States.

29 Jul 2019

Thin photoelectric film can stimulate degenerated retinal tissues

In a study recently published in Advanced Biomedical Engineering, researchers at Okayama University report a thin photoelectric film which can stimulate degenerated retinal tissues of the eye.

29 Jul 2019