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Study may offer an unexpected pathway for targeted treatment of brain tumors

In a new study led by Yale Cancer Center, researchers show the nucleoside transporter ENT2 may offer an unexpected path to circumventing the blood-brain barrier (BBB) and enabling targeted treatment of brain tumors with a cell-penetrating anti-DNA autoantibody.

15 Jun 2021

Research provides insights into why COVID-19 patients develop severe blood clots

Scientists have identified how and why some Covid-19 patients can develop life-threatening clots, which could lead to targeted therapies that prevent this from happening.

15 Jun 2021

Prenatal exposure to air pollutants may increase infants' obesity risk

Women exposed to higher levels of air pollution during pregnancy have babies who grow unusually fast in the first months after birth, putting on excess fat that puts them at risk of obesity and related diseases later in life, new CU Boulder research shows.

15 Jun 2021

Adapting COVID-19 vaccination strategies based on SARS-CoV-2’s evolution

Given the risk of SARS-CoV-2 developing new variants in unvaccinated individuals, vaccination sites are crucial. However, new research from the University of Michigan, USA, shows current vaccination programs may be worsening regional outbreaks when viral strains and SARS-CoV-2 escape mutations outdo vaccination rates.

15 Jun 2021

RBD and NTD antibody cocktail could prevent the emergence of SARS-CoV-2 escape mutants

A new bioRxiv* preprint demonstrates how a combination of antibodies to two different regions on the viral spike could enhance neutralization efficiency as well as prevent the emergence of resistant variants.

15 Jun 2021

Weather conditions made no impact on people’s mental health during Covid-19 pandemic

Come rain or shine, the weather did nothing to ease or worsen the mental health consequences of Covid-19 - according to new research from the University of East Anglia and the University of Essex.

15 Jun 2021

Being vaccinated doesn’t mean you must go maskless. Here’s why.

For more than a year, public health officials have repeatedly told us that masks save lives. They've warned us to keep our distance from our neighbors, who've morphed into disease vectors before our eyes.

15 Jun 2021

Does the number of siblings you have affect your health?

News-Medical spoke to Professor Peter M Nilsson about cardiovascular disease risk and whether this is affected by the number of siblings you have.

15 Jun 2021

Benefits and Challenges for XpressAmp™ Direct Amplification Reagents

News-Medical interviews Curtis Knox, Sr Strategic Portfolio Manager at Promega, about using the XpressAmp™ for the direct amplification of reagents.

From Promega Corporation 15 Jun 2021

The Role of Nanoparticles for Drug Delivery

In this interview, Mark Bumiller, Technology Manager at Entegris talks to News Medical Life Sciences about the role nanoparticles can play in drug delivery.

From Entegris, Inc. 15 Jun 2021

Novel biomarker effectively detects Alzheimer's disease before symptoms emerge

A newly developed radiotracer can measure increases in brain tau at least a year prior to the emergence of other symptoms.

15 Jun 2021

Alkaloids show potential as treatments for COVID-19

To further study these organic compounds, researchers from Kermanshah University of Medical Sciences, Iran, and Universidad de Santiago de Chile, Chile, reviewed the role of alkaloids as a potential antiviral, specifically against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They presented the chemistry, plant sources, and antiviral effects of alkaloids and their anti-SARS-CoV-2 effect.

15 Jun 2021

Weight-based dosing strategy may affect immunotherapy outcomes, shows study

Overweight cancer patients receiving immunotherapy treatments live more than twice as long as lighter patients, but only when dosing is weight-based, according to a study by cancer researchers at UT Southwestern Medical Center.

15 Jun 2021

Analysis of COVID-19 patients with repeatedly positive SARS-CoV-2 tests

New research published on the medRxiv preprint server provides a detailed analysis of COVID-19 patients who had repeated positive PCR tests for SARS-CoV-2 infection in a large US COVID-19 electronic health record (EHR) database.

15 Jun 2021

Rural Missouri counties experience nursing shortages at a greater rate, shows study

While the United States faces a nationwide nursing shortage, a recent study at the University of Missouri found rural Missouri counties experience nursing shortages at a greater rate than the state's metropolitan counties.

15 Jun 2021

Immune memory responses differ between SARS-CoV-2 and influenza A

Researchers in Canada have shown that the long-lasting immunity that develops following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by different T cell responses than those observed for influenza A virus-specific immune memory.

14 Jun 2021

SARS-CoV-2 variant of concern could cause further epidemics in UK

The team – from the University of Warwick, the University of Manchester, and the University of Oxford – say that a variant of concern that has either a substantial transmission advantage over resident lineages, or the ability to evade vaccine- or infection-induced immunity, can be expected to drive a wave of infections and hospitalizations similar to that seen in the country during the winter of 2020-21.

14 Jun 2021

Plasma zinc status not an effective prognostic factor for hospitalized COVID-19 patients

Due to previous evidence suggesting that zinc deficiencies can lead to complications along with an impaired antiviral response, a group of international researchers has undertaken a prospective observational study to investigate this association further.

14 Jun 2021

New wound gap closure mechanism may offer faster, better healing after injury or surgery

The observation of a previously undetected biological mechanism for closing gaps in living tissue improves basic understanding of the wound-healing process and may one day inform strategies to speed healing after surgery, according to a team of Penn State and Singapore researchers.

14 Jun 2021

Study uncovers novel drug that effectively thwarts pancreatic tumors

Pancreatic cancer is an aggressive disease in which malignant cells form in the tissues of the pancreas, a long and flat gland located behind the stomach that helps with digestion and blood sugar regulation.

14 Jun 2021