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UMDNJ biochemist to research into mechanisms that control gene expression in mitochondria

Dmitry Temiakov, PhD, a biochemist at the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, has received a five-year, $1.5 million grant from the National Institutes of Health (NIH) to fund research into the molecular mechanisms that control gene expression in mitochondria, the organelles that are the "power plants" of cellular activity.

1 Mar 2013

Blocking aPKC activity can stop growth of transplanted skin tumors resistant to vismodegib

Hailed as a major step forward in the effort to develop targeted cancer therapies, a recently approved drug for the most common type of skin cancer has been a mixed blessing for patients. Although the initial response is usually dramatic, the tumors often recur as the cancer becomes resistant to treatment.

28 Feb 2013

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.

28 Feb 2013

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

According to a recent University of Eastern Finland (UEF) study, elevated cell sugar concentrations increase the production of hyaluronan which, in turn, promotes cancer growth. Regulating the production of hyaluronan may be a way to prevent the spreading of cancer.

28 Feb 2013

Wyss Founding Director receives NC3Rs 3Rs Prize for Lung-on-a-Chip

In a London ceremony today, Wyss Founding Director Don Ingber, M.D., Ph.D., received the NC3Rs 3Rs Prize from the UK's National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) for his innovative Lung-on-a-Chip -- a microdevice lined by human cells that recapitulates complex functions of the living lung.

28 Feb 2013

Researchers identify 25 human proteins that may be crucial for HIV-1 infection and survival

Studying HIV-1, the most common and infectious HIV subtype, Johns Hopkins scientists have identified 25 human proteins "stolen" by the virus that may be critical to its ability to infect new cells. HIV-1 viruses capture many human proteins from the cells they infect but the researchers believe these 25 proteins may be particularly important because they are found in HIV-1 viruses coming from two very different types of infected cells.

28 Feb 2013

MenB bacterium uses Adhesin Complex Protein to stick to human cells

Scientists at the University of Southampton have taken a significant and important step in keeping people safe from the most common form of meningitis in the UK.

28 Feb 2013

Recombinant Newcastle disease virus kills all kinds of prostate cancer cells

A recombinant Newcastle disease virus kills all kinds of prostate cancer cells, including hormone resistant cells, but leaves normal cells unscathed, according to a paper published online ahead of print in the Journal of Virology.

26 Feb 2013

New, effective and less toxic therapeutic option for patients with HER2-positive breast cancer

Patients with HER2-positive breast cancer, a particularly aggressive form of breast cancer, now have a new, effective and less toxic therapeutic option.

24 Feb 2013

Antibody delivery system launched that works even in presence of additives

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22 Feb 2013

Scientists uncover atomic structure of dermcidin

An international team of scientists has discovered how an important natural antibiotic called dermcidin, produced by our skin when we sweat, is a highly efficient tool to fight tuberculosis germs and other dangerous bugs.

22 Feb 2013

Researchers identify second B-cell attachment receptor for Epstein-Barr virus

Epstein-Barr virus (EBV) affects more than 90 percent of the population worldwide and was the first human virus found to be associated with cancer. Now, researchers from Beth Israel Deaconess Medical Center (BIDMC) have broadened the understanding of this widespread infection with their discovery of a second B-cell attachment receptor for EBV.

21 Feb 2013

Expert to explain how extremely stable gold nanoparticles can be used in medicine

A nanoscale science expert will explain how extremely stable gold nanoparticles can be used in medicine. Professor Mathias Brust, of the University of Liverpool, will give his lecture Monolayer Protected Clusters of Gold: Building Blocks, Functional Materials, Macromolecules, Biomedical Tools and more at the University of Leicester on Thursday, February 21.

20 Feb 2013

Liposomes not capable of transporting themselves deep into the skin

Liposomes are small fat capsules, often added to beauty products. According to the beauty industry liposomes are capable of transporting active ingredients deep into the skin and release the active ingredients so that they can alter the skin-s structure by rejuvenating and smoothing the skin.

20 Feb 2013

FSH, LH two important hormones that regulate puberty and maturation processes

FSH and LH are two important hormones which regulate the processes of puberty and maturation. These hormones are secreted by the pituitary gland and are transported in the blood to the genitalia, where they regulate maturation.

19 Feb 2013

New materials mimic mussel adhesive proteins for three medical applications

When it comes to sticking power under wet conditions, marine mussels are hard to beat. They can adhere to virtually all inorganic and organic surfaces, sustaining their tenacious bonds in saltwater, including turbulent tidal environments.

18 Feb 2013

Two studies discover new enzyme that acts as a sensor of innate immunity

Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.

16 Feb 2013

New insights into how cells stick to each other and to other bodily structures

Research carried out by scientists at the Georgia Institute of Technology and The University of Manchester has revealed new insights into how cells stick to each other and to other bodily structures, an essential function in the formation of tissue structures and organs. It's thought that abnormalities in their ability to do so play an important role in a broad range of disorders, including cardiovascular disease and cancer.

15 Feb 2013

Second Sight Medical Products receives FDA approval for Argus II Retinal Prosthesis System

The U.S. Food and Drug Administration today approved the Argus II Retinal Prosthesis System, the first implanted device to treat adult patients with advanced retinitis pigmentosa (RP).

14 Feb 2013

FOXC2 vital to epithelial-mesenchymal transition in breast cancer

Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.

14 Feb 2013

Membrane News and Research

UMDNJ biochemist to research into mechanisms that control gene expression in mitochondria

Blocking aPKC activity can stop growth of transplanted skin tumors resistant to vismodegib

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

Wyss Founding Director receives NC3Rs 3Rs Prize for Lung-on-a-Chip

Researchers identify 25 human proteins that may be crucial for HIV-1 infection and survival

MenB bacterium uses Adhesin Complex Protein to stick to human cells

Recombinant Newcastle disease virus kills all kinds of prostate cancer cells

New, effective and less toxic therapeutic option for patients with HER2-positive breast cancer

Antibody delivery system launched that works even in presence of additives

Scientists uncover atomic structure of dermcidin

Researchers identify second B-cell attachment receptor for Epstein-Barr virus

Expert to explain how extremely stable gold nanoparticles can be used in medicine

Liposomes not capable of transporting themselves deep into the skin

FSH, LH two important hormones that regulate puberty and maturation processes

New materials mimic mussel adhesive proteins for three medical applications

Two studies discover new enzyme that acts as a sensor of innate immunity

New insights into how cells stick to each other and to other bodily structures

Second Sight Medical Products receives FDA approval for Argus II Retinal Prosthesis System

FOXC2 vital to epithelial-mesenchymal transition in breast cancer

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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