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Vosoritide's first phase 2 study shows increased growth in children with hypochondroplasia

Vosoritide's first global phase 2 study showed an average increased growth rate of 1.8 cm per year in children with hypochondroplasia, a genetic cause of short stature in children, according to researchers from Children's National Hospital.

13 Apr 2024

Wearable devices reveal stress-related changes during sleep

What if changes in a person's stress levels could be detected while they sleep using wearable devices? A new study by University of Vermont researchers published today in PLOS Digital Health is the first to find changes in perceived stress levels reflected in sleep data - an important step towards identifying biomarkers that may help flag individuals in need of support.

13 Apr 2024

Hypoglossal nerve stimulation offers hope for pediatric Down syndrome patients with OSA

While Obstructive Sleep Apnea (OSA) affects about five percent of the general pediatric population, 80 percent of children with Down syndrome experience OSA. Continual OSA results in poor health, including disruptions to cognitive development and functioning, leading physician-researchers from Mass General Brigham to investigate better methods to treat these patients as early as possible to maximize their health outcomes.

12 Apr 2024

Nearly 1 in 4 adults dumped from Medicaid are now uninsured, survey finds

Nearly a quarter of adults disenrolled from Medicaid in the past year say they are now uninsured, according to a survey released Friday that details how tens of millions of Americans struggled to retain coverage in the government insurance program for low-income people after pandemic-era protections began expiring last spring.

12 Apr 2024

Study provides valuable insights into the DCB-only strategy for left main coronary artery disease

Sanna Uskela et al., at North Karelia Central Hospital-Heart Center, Finland, conducted a retrospective single-center registry study that focused on the use of drug-coated balloon (DCB)-only strategy for treating de novo left main coronary artery disease.

12 Apr 2024

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Sex differences are widespread across human development, physiological processes, and diseases, making it important to characterize the impact of sex differences in these areas.

12 Apr 2024

Revolutionizing heart failure treatment: Advances in mechanical circulatory support devices

The same technology that enables a bullet train to travel at speeds up to 200 mph without touching its rails now keeps a failing heart pumping - and in the near future, it will do so via a wireless power connection.

12 Apr 2024

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

A noninvasive brain stimulation treatment improved depression and anxiety symptoms among older adults in a new University of Florida-led study.

12 Apr 2024

Is psilocybin safe for treating depression and anxiety?

A study in JAMA Network Open examined the acute adverse effects of therapeutic doses of psilocybin for treating depression and anxiety, focusing on its safety profile by assessing the occurrence of immediate side effects like headache, nausea, and elevated blood pressure among others.

12 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

New lab assay could make diagnosis and treatment of lung cancer easier

A new lab assay developed by researchers at Fred Hutch Cancer Center could make diagnosis and treatment of small-cell lung cancer and non-small cell lung cancer easier.

10 Apr 2024

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease.

10 Apr 2024

New sleep-enhancing nutraceutical blend falls short in clinical trial

Study investigates the impact of a unique nutraceutical blend, combining L-theanine with valerian, saffron, and lemon balm extracts, on improving sleep quality, finding no significant difference compared to a placebo in individuals experiencing poor sleep.

10 Apr 2024

Three-step prostate cancer screening method demonstrates reduced overdiagnosis

A large randomized trial conducted at Tampere University and the University of Helsinki shows that a new three-step prostate cancer screening method can find a considerable number of aggressive cancers.

10 Apr 2024

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH).

10 Apr 2024

New natural supplement shows promise in preventing postpartum blues

A new study published in the Lancet discovery science journal eClinicalMedicine has confirmed that a novel natural supplement - invented, researched, developed and commercialized at the Centre for Addiction and Mental Health (CAMH) - prevents postpartum blues, and reduces symptoms of postpartum depression over the following six months after giving birth.

10 Apr 2024

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.

10 Apr 2024

Novel immune cell therapy may be a promising strategy for combating HBV infection

Chronic infection with the hepatitis B virus (HBV) causes progressive liver problems, and eradication of the virus remains a formidable challenge.

10 Apr 2024

Study provides reassurance regarding the safety of using hormone therapy after age 65 years

After the Women's Health Initiative (WHI) in 2002, many women have resisted taking hormone therapy (HT), especially after age 65 years, because of fears of increased risks for various cancers and heart disease.

10 Apr 2024

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

Three early-phase clinical studies presented by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2024 show promising initial data for patients with lymphoma, gastric or gastroesophageal junction cancers, and specific molecularly selected tumors.

10 Apr 2024

Therapy News and Research

Vosoritide's first phase 2 study shows increased growth in children with hypochondroplasia

Wearable devices reveal stress-related changes during sleep

Hypoglossal nerve stimulation offers hope for pediatric Down syndrome patients with OSA

Nearly 1 in 4 adults dumped from Medicaid are now uninsured, survey finds

Study provides valuable insights into the DCB-only strategy for left main coronary artery disease

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Revolutionizing heart failure treatment: Advances in mechanical circulatory support devices

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

Is psilocybin safe for treating depression and anxiety?

Tumor microbiomes offer new insights for enhancing cancer therapies

New lab assay could make diagnosis and treatment of lung cancer easier

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

New sleep-enhancing nutraceutical blend falls short in clinical trial

Three-step prostate cancer screening method demonstrates reduced overdiagnosis

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

New natural supplement shows promise in preventing postpartum blues

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

Novel immune cell therapy may be a promising strategy for combating HBV infection

Study provides reassurance regarding the safety of using hormone therapy after age 65 years

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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