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Researchers launch clinical trial to assess therapeutic drug monitoring for patients with inflammatory diseases

New research presented at ACR Convergence, the American College Rheumatology's annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care.

8 Nov 2020

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

A team of researchers from various institutes across Pakistan, Chile, Canada, and the USA recently conducted a clinical trial to investigate the potential effectiveness of a combination of honey and Nigella sativa (HNS) in treating COVID-19 patients. Their study is published on the preprint server medRxiv prior to the scientific peer review process.

8 Nov 2020

FDA authorizes marketing of new device intended to provide temporary relief from sleep disturbances

Today, the U.S. Food and Drug Administration permitted marketing of a new device intended for the temporary reduction of sleep disturbance related to nightmares in adults 22 years or older who suffer from nightmare disorder or have nightmares from post-traumatic stress disorder (PTSD).

8 Nov 2020

TB screening needed for people on methotrexate who live in at-risk areas

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that tuberculosis (TB) screening and ongoing clinical care is needed for people on methotrexate who live in areas where the highly infectious illness is common.

6 Nov 2020

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

6 Nov 2020

Rapid rise in CRP levels predicts COVID-19 outcomes

Predicting the course of a COVID-19 patient's disease after hospital admission is essential to improving treatment.

6 Nov 2020

Repurposing an anxiety drug to increase the efficacy of therapies for metastatic melanoma

There are times when adding something new to the mix makes it better. Give Popeye some spinach, and you've got a fighting machine. Give Mario a mushroom, and he becomes invincible. Without drinking a potion, Alice in Wonderland would never fit through the door.

5 Nov 2020

Study investigates the ebb and flow of brain ventricles

Enlarged ventricles in the brains of people with multiple sclerosis were previously considered a sign of tissue loss.

5 Nov 2020

UH professor is developing a Chinese herbal medicine formula to improve cancer therapy

University of Houston professor of pharmaceutics Ming Hu is developing and testing an ancient Chinese herbal medicine formula, first described in 280 A.D., to improve cancer therapy.

4 Nov 2020

App-delivered computerized brain-training helps prevent alcohol relapse

A recent study has shown that it may be possible to dampen the workings of the subconscious brain to prevent alcohol relapse, the results leading to a world-first trial of a personalised smartphone app called "SWiPE".

4 Nov 2020

Study elucidates mechanisms behind protective farm effect on childhood asthma

Asthma impacts millions of children already at a young age. Children growing up on a farm have a lower risk of developing asthma than children not living on a farm.

2 Nov 2020

Study identifies new cause of COVID-19 blood clots

Blood clots continue to wreak havoc for patients with severe COVID-19 infection, and a new study explains what may spark them in up to half of patients.

2 Nov 2020

Drug used to control blood pressure may improve cancer patients’ response to immunotherapy

The same biochemical triggers that spur a "fight or flight" response when we encounter threats may help tumor cells to thrive.

30 Oct 2020

Potential treatment might make tumors more responsive to immunotherapy

Cancer immunotherapies, which empower patients' immune systems to eliminate tumors, are revolutionizing cancer treatment. Many patients respond well to these treatments, sometimes experiencing long-lasting remissions.

30 Oct 2020

UIC enrolls people into phase 3 monoclonal antibody clinical trial

Researchers at the University of Illinois Chicago are now enrolling people into a phase 3 clinical trial that will test if a monoclonal antibody treatment -- administered as a series of four shots -- will help protect uninfected individuals from acquiring or getting sick from COVID-19 after someone in the household tests positive for COVID-19.

30 Oct 2020

Beetroot peptide may be a good candidate for development of a drug to treat inflammatory diseases

In a recent study, a research group led by Christian Gruber at MedUni Vienna's Institute of Pharmacology isolated a peptide (small protein molecule) from beetroot.

30 Oct 2020

New mouth spray could help treat patients with rare genetic skin condition

A new spray for treating severely painful blisters, mouth ulceration and oral scarring in patients with a rare genetic skin condition is being developed by researchers at the University of Birmingham.

29 Oct 2020

UH and CWRU announce Phase 3 trial of Astrazeneca's investigational COVID-19 vaccine

University Hospitals and Case Western Reserve University announced today that UH Cleveland Medical Center has been selected as a clinical trial site for the Phase 3 global study of an investigational vaccine against SARS-CoV-2, sponsored by AstraZeneca.

29 Oct 2020

High dose radiation therapy linked to shorter survival times in NSCLC patients

A genetic analysis of non-small cell lung cancer (NSCLC) patients on the phase III NRG Oncology RTOG 0617 clinical trial assessing radiation dose discovered that high dose radiation therapy is associated with shorter survival times among patients with a radiation-sensitive genotype in DNA repair pathway.

29 Oct 2020

Glucose-lowering drug can protect the kidneys in patients with type 1 diabetes, study shows

A glucose-lowering drug commonly used in patients with type 2 diabetes, can protect the kidneys in patients with type 1 diabetes. According to results shown in a new study published in the Lancet.

28 Oct 2020

Clinical Trial News and Research

Researchers launch clinical trial to assess therapeutic drug monitoring for patients with inflammatory diseases

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

FDA authorizes marketing of new device intended to provide temporary relief from sleep disturbances

TB screening needed for people on methotrexate who live in at-risk areas

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

Rapid rise in CRP levels predicts COVID-19 outcomes

Repurposing an anxiety drug to increase the efficacy of therapies for metastatic melanoma

Study investigates the ebb and flow of brain ventricles

UH professor is developing a Chinese herbal medicine formula to improve cancer therapy

App-delivered computerized brain-training helps prevent alcohol relapse

Study elucidates mechanisms behind protective farm effect on childhood asthma

Study identifies new cause of COVID-19 blood clots

Drug used to control blood pressure may improve cancer patients’ response to immunotherapy

Potential treatment might make tumors more responsive to immunotherapy

UIC enrolls people into phase 3 monoclonal antibody clinical trial

Beetroot peptide may be a good candidate for development of a drug to treat inflammatory diseases

New mouth spray could help treat patients with rare genetic skin condition

UH and CWRU announce Phase 3 trial of Astrazeneca's investigational COVID-19 vaccine

High dose radiation therapy linked to shorter survival times in NSCLC patients

Glucose-lowering drug can protect the kidneys in patients with type 1 diabetes, study shows

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