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Global increase in deaths from viral hepatitis revealed in WHO report

According to the World Health Organization (WHO) 2024 Global Hepatitis Report, the number of lives lost due to viral hepatitis is increasing.

10 Apr 2024

Bio-Techne surpasses 10,000 peer-reviewed publications citing RNAscope technology

Bio-Techne Corporation today announced that Advanced Cell Diagnostics (ACD), part of Bio-Techne's Spatial Biology Division, has surpassed 10,000 peer-reviewed publications referencing the use and application of RNAscope™ ISH technology.

From Bio-Techne 9 Apr 2024

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems - prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

9 Apr 2024

Researchers compile a comprehensive catalog of bacteria living in cancer metastases

Researchers at the Netherlands Cancer Institute have compiled a detailed catalog of bacteria living in cancer metastases.

9 Apr 2024

Electroconvulsive Therapy found to be safe and effective treatment for some mental illnesses

Researchers have found that Electroconvulsive Therapy (ECT), where an electric current is passed through the brain, can reduce the severity of mental illnesses.

9 Apr 2024

Beta-blockers show no benefit for heart attack patients with normal heart function

The REDUCE-AMI trial found that long-term beta-blocker therapy does not reduce mortality risk in acute myocardial infarction patients with preserved left ventricular ejection fraction compared to no beta-blocker treatment.

8 Apr 2024

Personalized anti-tumor vaccine enhances immunotherapy for liver cancer

Adding a personalized anti-tumor vaccine to standard immunotherapy is safe and about twice as likely to shrink cancer as standard immunotherapy alone for patients with hepatocellular carcinoma, the most common type of liver cancer, according to a clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and its Convergence Institute.

8 Apr 2024

Preventive PCI reduces cardiac event risks in patients with high-risk plaque

People with a buildup of fatty atherosclerotic plaque in the heart's arteries considered at risk of rupturing were far less likely to suffer a serious cardiac event if they underwent percutaneous coronary intervention (PCI), a procedure to open blocked arteries, compared with those who took medications alone but did not undergo PCI, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

The investigational drug ninerafaxstat showed a good tolerability and safety profile, along with evidence of improvements in symptoms and exercise capacity among people with nonobstructive hypertrophic cardiomyopathy (HCM), according to results of a 12-week phase 2 trial presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Novel signaling pathway identified in lysosome damage response

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm.

8 Apr 2024

Preventive ventricular tachycardia ablation cuts down ICD shocks and hospitalizations

The first randomized trial to investigate preventive ablation of a potential arrhythmogenic substrate associated with coronary chronic total occlusion (CTO) in patients at high risk of ventricular arrhythmias (VAs) reduces the risk of appropriate implantable cardioverter-defibrillator (ICD) therapy and unplanned hospitalization in patients with no previously recorded VAs.

8 Apr 2024

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

8 Apr 2024

First-ever guidelines developed to help build a child's tolerance to common food allergens

Researchers with McMaster University have crafted the first-ever guidelines to help prepare families who plan to build their child's tolerance to common food allergens.

8 Apr 2024

Immersive VR may be a useful non-medication strategy to improve cancer pain

A 10-minute virtual reality (VR) session significantly lessened pain in hospitalized patients with cancer in a recent clinical trial published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. Even a day later, participants experienced sustained benefits.

8 Apr 2024

NeuM technology revolutionizes neuron labeling for neurodegenerative disease research

Alzheimer's disease and Parkinson's disease, along with stroke, are among the top three neurodegenerative disorders, characterized by the malfunction and progressive degeneration of neurons, the nerve cells.

8 Apr 2024

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

A new technology using ultralow temperature cryoablation (ULTC) has eliminated clinical ventricular tachycardia (VT) in 94% of patients. The late-breaking science is presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).

8 Apr 2024

Edetate disodium-based chelation ineffective for heart attack patients with diabetes

People with diabetes who had suffered a heart attack derived no clinical benefit from edetate disodium-based chelation, a therapy that draws lead and other toxic metals linked to increased risk of heart disease and stroke out of the body, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Lerodalcibep reduces LDL cholesterol by over 50% in high-risk patients

Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or "bad" cholesterol, levels by more than half on average, compared with a placebo.

8 Apr 2024

Impella CP pump shows survival benefit in cardiogenic shock

Implantation of the Impella CP micro-axial flow pump in the hours after a heart attack significantly increased the rate of survival at six months among people suffering cardiogenic shock, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Therapy News and Research

Global increase in deaths from viral hepatitis revealed in WHO report

Bio-Techne surpasses 10,000 peer-reviewed publications citing RNAscope technology

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Researchers compile a comprehensive catalog of bacteria living in cancer metastases

Electroconvulsive Therapy found to be safe and effective treatment for some mental illnesses

Beta-blockers show no benefit for heart attack patients with normal heart function

Personalized anti-tumor vaccine enhances immunotherapy for liver cancer

Preventive PCI reduces cardiac event risks in patients with high-risk plaque

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

Novel signaling pathway identified in lysosome damage response

Preventive ventricular tachycardia ablation cuts down ICD shocks and hospitalizations

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

First-ever guidelines developed to help build a child's tolerance to common food allergens

Immersive VR may be a useful non-medication strategy to improve cancer pain

NeuM technology revolutionizes neuron labeling for neurodegenerative disease research

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

Edetate disodium-based chelation ineffective for heart attack patients with diabetes

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

Lerodalcibep reduces LDL cholesterol by over 50% in high-risk patients

Impella CP pump shows survival benefit in cardiogenic shock

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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