Genetic News and Research

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Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

A Stanford Medicine-led, international study of hundreds of samples from patients with Hodgkin lymphoma has shown that levels of tumor DNA circulating in their blood can identify who is responding well to treatment and others who are likely to experience a disease recurrence - potentially letting some patients who are predicted to have favorable outcomes forgo lengthy treatment.

11 Dec 2023

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer.

11 Dec 2023

New drug combo shows promise in targeting RAS-mutant multiple myeloma

The combination of a drug and a protein fragment prevents the growth of blood cancer cells, a new study in mice shows.

11 Dec 2023

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

A new study from researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations provides insight into the underlying mechanisms of gene mutations commonly seen in patients with myelodysplastic syndromes (MDS) and other myeloid neoplasms.

11 Dec 2023

MD Anderson researchers report early success of novel menin-targeted therapies in leukemia

Two clinical trials led by researchers from The University of Texas MD Anderson Cancer Center demonstrated early positive results from novel therapies targeting menin for the treatment of relapsed or refractory acute leukemias with specific genetic alterations.

11 Dec 2023

New proposals to change donor anonymity laws may increase inconsistency and unfairness, experts warn

New proposals to change the law protecting the anonymity of sperm and egg donors in the UK “would increase inconsistency and arguably unfairness” for many donor-conceived people, two experts in the field have warned.

11 Dec 2023

New atlas characterizes cellular landscape of the early human limb

Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured for the first time as scientists unveil a spatial cell atlas of the entire developing human limb, resolved in space and time.

11 Dec 2023

Groundbreaking online community connects Progeria patients worldwide

A ground-breaking online community has been launched to allow people with the rare disease Progeria to communicate regardless of their location or language.

11 Dec 2023

New map offers valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer

Scientists have created the first extensive map showing how all possible genetic changes can affect health in the gene DDX3X, leading to valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer.

11 Dec 2023

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Using machine learning, researchers successfully distinguished factors of healthy aging from chronic disease risks by analyzing health data across various ages, finding key markers like neutrophil counts and alkaline phosphatase levels as early indicators of healthy aging.

10 Dec 2023

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Viruses have limited genetic material - and few proteins - so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins.

8 Dec 2023

Many patients may not benefit from gene-editing treatments for sickle cell disease

Federal approval of a breakthrough gene-editing technology that treats the pain and debilitating effects of sickle cell disease is cause for celebration among a community with few options for relief.

8 Dec 2023

Genome-wide study shows strong negative correlation between reproduction and lifespan

A University of Michigan-led study based on a review of genetic and health information from more than 276,000 people finds strong support for a decades-old evolutionary theory that sought to explain aging and senescence.

8 Dec 2023

Scientists decode key factor in T cell lymphoma growth, paving way for new treatments

A team from the Technical University of Munich (TUM) has decoded the factor that makes T cell lymphomas grow comparatively rapidly: A missing "emergency shut-off switch" results in the lymphomas processing particularly large amounts of sugar and triggers other processes as well.

8 Dec 2023

Genetic News and Research

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

New drug combo shows promise in targeting RAS-mutant multiple myeloma

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

MD Anderson researchers report early success of novel menin-targeted therapies in leukemia

New proposals to change donor anonymity laws may increase inconsistency and unfairness, experts warn

New atlas characterizes cellular landscape of the early human limb

Groundbreaking online community connects Progeria patients worldwide

New map offers valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Study unlock secrets of Zika virus's multipurpose enzyme and reveals therapeutic vulnerability

Many patients may not benefit from gene-editing treatments for sickle cell disease

Genome-wide study shows strong negative correlation between reproduction and lifespan

Scientists decode key factor in T cell lymphoma growth, paving way for new treatments

Closing the gender gap in HIV treatment could slash infection rates in Uganda

Plant-based diets and genetic risk for obesity

How did machine learning models perform in identifying hepatitis in patients with diabetes?

Key gene linked to male bias in autism, Tourette's, and ADHD uncovered

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Researchers identify 25 new genetic markers linked to peptic ulcers

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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