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Cutting around 300 calories a day protects the heart even in svelte adults

New data from a two-year Duke Health trial suggests when it comes to cutting your risk for killer ailments such as diabetes and heart disease, there's always room for improvement.

12 Jul 2019

New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

In collaborative research, scientists from three continents were able to discover a crucial bit of information about how T cells move proteins inside them to drive the immune response. This could help evolve specific new treatments centered on T cell selectivity.

12 Jul 2019

Two New Resistance-Proof Antibiotics Have Been Created

Antibiotic resistance is a growing global concern. Two new resistance-proof antibiotics have been created at the Inserm and Université de Rennes 1.

11 Jul 2019

Liver fat biomarker levels linked with metabolic health benefits of exercise, study finds

While genetics and other factors like age and sex contribute to each individual's response to exercise, little is known about the biological mechanisms by which physical activity brings about beneficial changes to the body.

11 Jul 2019

Researchers explain how 'viral' agents of neurological diseases ended up in our DNA

What if the missing ‘environmental’ factor in some of our deadliest neurological diseases were really written in our genome?

11 Jul 2019

New drug provides hope for patients with Duchenne muscular dystrophy

The results from three clinical trials have shown that a new drug can successfully delay the progression of Duchenne muscular dystrophy.

10 Jul 2019

New study to ease plight of patients with advanced cancer

Patients with advanced cancer are to test a therapy aimed at reducing their symptoms and improving quality of life.

10 Jul 2019

Sorting protein in neurons protects against neurodegenerative disorders

Like a sorting machine in an assembly line, a molecule known as VPS35 detects and removes defective proteins from neurons.

10 Jul 2019

Israeli scientists invent new tooth fillings to fight recurrent decay

Almost everyone experiences tooth decay (caries), it seems, making this among the most common conditions caused by bacterial infection. The costs of treating this condition are among the highest for bacterial conditions

10 Jul 2019

Hinge-like protein may unlock new pathways for cystic fibrosis treatment

In recent decades, treatment options for people with cystic fibrosis have improved dramatically. The newest drugs, known as potentiators, target a protein called cystic fibrosis transmembrane conductance regulator, which is mutated in people with the disease.

10 Jul 2019

UM scientists receive $3.3 million NIH contract to develop opioid addiction vaccine

The University of Montana has received a $3.3 million contract from the National Institutes of Health to develop an innovative vaccine targeting opioid addiction.

10 Jul 2019

New class of cancer-killing agents shows promise in destroying cancer stem cells

Scientists at The University of Toledo investigating improvements to a commonly used chemotherapy drug have discovered an entirely new class of cancer-killing agents that show promise in eradicating cancer stem cells.

9 Jul 2019

Collagen powder found to be effective in wound closure

Collagen powder is just as effective in managing skin biopsy wounds as primary closure with non-absorbable sutures, according to a first-of-its-kind study published in the Journal of Drugs in Dermatology by a team of physician researchers at the George Washington University.

8 Jul 2019

Researchers develop new technique to enhance infection-fighting potential of natural chemicals

Researchers in Japan have identified multiple promising new drug candidates to treat antibiotic-resistant infections, including the superbug MRSA (methicillin-resistant Staphylococcus aureus).

8 Jul 2019

Common cold virus strain could be a breakthrough in bladder cancer treatment

Scientists in the UK have found a new way to treat bladder cancer, using a strain of one of the viruses that cause the common cold. The virus is called Coxsackie virus CVA21, and it was found to be oncolytic, or tumor-destroying.

8 Jul 2019

Researchers discover novel cancer-promoting molecular mechanism

A novel cancer-promoting molecular mechanism has been discovered by Pierluigi Scalia, M.D., Ph.D., with his co-workers at the Sbarro Institute for Cancer Research and Molecular Medicine, Division of Biology, Temple University, the Department of Medical Biotechnologies at University of Siena, Italy and the Italian non-profit research organization ISOPROG, in collaboration with the Center of Biocomputational Sciences, part of the College of Science and Technology in Philadelphia.

8 Jul 2019

Study reports role of cancer gene in tumor microenvironment

The tumor microenvironment is a mix of fluids, immune cells and blood vessels which envelops the tumors. Interactions between tumor cells and the TME determine the progression and fate of tumors.

4 Jul 2019

HER2-positive breast cancer may be treated with imprinted nanospheres

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles “imprinted” with specific binding sites for the receptor molecule HER2.

4 Jul 2019

Findings suggest new ways to help the immune system fight pancreatic cancer

Findings published today in the journal Science Translational Medicine suggest that a type of white blood cell called tumor associated macrophages that have been deceived by pancreatic cancer cells into not attacking them can be "re-programmed" by a specially designed molecule that activates a protein found on their surfaces.

4 Jul 2019

Hesperos' multi-organ model correctly determine cardiotoxic mechanisms

Hesperos Inc., pioneers of the "human-on-a-chip" in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo.

4 Jul 2019