Preclinical News and Research

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Ludwig, Agenus to advance three monoclonal antibody checkpoint modulators into preclinical development

Ludwig Cancer Research and Agenus Inc. today announced the selection of three monoclonal antibody checkpoint modulators (CPMs) that Agenus is advancing into preclinical development.

7 Mar 2014

Ohr Pharmaceutical partners with CSHL to develop trodusquemine and related analogs

Ohr Pharmaceutical, a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, and leading global cancer research center Cold Spring Harbor Laboratory (CSHL) today announced the establishment of DepYmed Inc., a new joint venture to develop trodusquemine and related analogs.

6 Mar 2014

Researcher wins grant from NCI to continue developing new therapy for bladder cancer

A biomedical engineering researcher at the University of Arkansas will use a $416,897 grant from the National Cancer Institute to continue developing a new therapy for bladder cancer.

6 Mar 2014

Tetraphase Pharmaceuticals reports net loss of $11.3 million for Q4 2013

Tetraphase Pharmaceuticals, Inc. today reported financial results for the quarter and full year ended December 31, 2013.

6 Mar 2014

Study to understand role of bacterium in heart valve disease

A disease-causing bacterium found in the mouth needs manganese, a trace mineral, in order to cause a serious heart infection, according to a preclinical study led by researchers at Virginia Commonwealth University Philips Institute for Oral Health Research in the School of Dentistry.

6 Mar 2014

Agenus reports net loss attributable to common stockholders of $5.8 million for Q4 2013

Agenus Inc., a biopharmaceutical company developing a portfolio of immuno-oncology candidates, including checkpoint modulators (CPMs), heat shock protein vaccines and adjuvants, today announced its financial results and business highlights for the fourth quarter and year ended December 31, 2013.

5 Mar 2014

Bruker opens new preclinical imaging center of excellence for the Americas

Bruker (NASDAQ: BRKR) today announced the official opening of a new Preclinical Imaging Center of Excellence for the Americas in Billerica, Massachusetts. The facility offers advanced development, demonstration and support facilities for Bruker’s industry-leading portfolio of preclinical imaging instrumentation and multimodal platforms.

4 Mar 2014

Omeros submits investigational new drug to initiate OMS721 Phase 2 clinical program

Omeros Corporation today announced that it has submitted to the U.S. Food and Drug Administration (FDA) an investigational new drug (IND) application to initiate the Phase 2 clinical program for OMS721, the company's lead human monoclonal antibody targeting mannan-binding lectin‑associated serine protease-2 (MASP-2), the key regulator of the lectin pathway of the immune system.

4 Mar 2014

GTx provides clinical updates, reports financial results for fourth quarter and full year 2013

GTx, Inc. today provided a Company update and reported financial results for the fourth quarter and full year 2013.

4 Mar 2014

Advanced Accelerator Applications agrees to acquire 100% shares of Imaging Equipment

Advanced Accelerator Applications, a fast growing international specialist in Molecular Nuclear Medicine (MNM), announced today that it has entered into an agreement to acquire 100% of the shares of Imaging Equipment Ltd, a privately-held UK distributor of nuclear medicine products and technologies, in newly issued AAA shares.

4 Mar 2014

Bruker launches new, improved customer-driven products at Pittcon 2014

At Pittcon 2014, Bruker today announced new product introductions and enhancements for improved performance and customer experience in research, industrial and applied markets.

4 Mar 2014

New research uncovers abnormal molecular signaling pathways for kidney failure

Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure.

4 Mar 2014

OPKO Health consolidated revenues increase about 30% to $20.7 million in Q4 2013

OPKO Health, Inc., a multi-national biopharmaceutical and diagnostics company, today reported operating and financial results for its 2013 fourth quarter and full year ended December 31, 2013.

4 Mar 2014

Naurex's GLYX-13 receives FDA Fast Track designation

Naurex Inc. today announced that the U.S. Food and Drug Administration has granted Fast Track designation to the investigation of GLYX-13, the company's rapid-acting antidepressant in Phase 2 clinical development, as adjunctive therapy in major depressive disorder.

4 Mar 2014

New molecule fluorogenic probe for rapid assessment of individual's risk for Parkinson's disease

A team of researchers from National University of Singapore (NUS) have created the first two-photon, small molecule fluorogenic probe that can serve as a useful tool for the rapid assessment of an individual's potential risk for Parkinson's disease.

3 Mar 2014

Microencapsulated drug delivery may soon revolutionize cancer treatment

Invasive and systemic cancer treatment is a necessary evil for many people with the devastating diagnosis. These patients endure therapies with ravaging side effects, including nausea, immune suppression, hair loss and even organ failure, in hopes of eradicating cancerous tissues in the body.

3 Mar 2014

Maximizing imaging techniques to bridge the gap between diagnosis and treatment of cancer

Glioblastoma multiforme is the most common form of brain cancer and patients with this diagnosis have a life expectancy of less than two years. In spite of the fact that its diagnosis is very good, an appropriate treatment remains elusive.

From Bruker BioSpin Group 3 Mar 2014

LA BioMed researchers awarded NIH grant to pursue new approaches for treating MRSA

With antibiotic resistant infections on the rise and a scarce pipeline of novel drugs to combat them, researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center are pursuing entirely new approaches to meet the challenge of drug-resistant infections by taming microbes rather than killing them.

27 Feb 2014

Opiate use alters activity of specific protein needed for normal functioning of brain's reward center

Identifying the specific pathways that promote opioid addiction, pain relief, and tolerance are crucial for developing more effective and less dangerous analgesics, as well as developing new treatments for addiction.

25 Feb 2014

IRSF announces new research grants for translational research program and clinical trials

The International Rett Syndrome Foundation (IRSF) announces today ten (10) new research grants at leading global research institutions; a new Translational Research Program; and additional funding for current human clinical trials.

24 Feb 2014

Preclinical News and Research

Ludwig, Agenus to advance three monoclonal antibody checkpoint modulators into preclinical development

Ohr Pharmaceutical partners with CSHL to develop trodusquemine and related analogs

Researcher wins grant from NCI to continue developing new therapy for bladder cancer

Tetraphase Pharmaceuticals reports net loss of $11.3 million for Q4 2013

Study to understand role of bacterium in heart valve disease

Agenus reports net loss attributable to common stockholders of $5.8 million for Q4 2013

Bruker opens new preclinical imaging center of excellence for the Americas

Omeros submits investigational new drug to initiate OMS721 Phase 2 clinical program

GTx provides clinical updates, reports financial results for fourth quarter and full year 2013

Advanced Accelerator Applications agrees to acquire 100% shares of Imaging Equipment

Bruker launches new, improved customer-driven products at Pittcon 2014

New research uncovers abnormal molecular signaling pathways for kidney failure

OPKO Health consolidated revenues increase about 30% to $20.7 million in Q4 2013

Naurex's GLYX-13 receives FDA Fast Track designation

New molecule fluorogenic probe for rapid assessment of individual's risk for Parkinson's disease

Microencapsulated drug delivery may soon revolutionize cancer treatment

Maximizing imaging techniques to bridge the gap between diagnosis and treatment of cancer

LA BioMed researchers awarded NIH grant to pursue new approaches for treating MRSA

Opiate use alters activity of specific protein needed for normal functioning of brain's reward center

IRSF announces new research grants for translational research program and clinical trials

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