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Scientists develop 3-D artificial enzyme cascade that mimics biochemical pathway using DNA molecules

Using molecules of DNA like an architectural scaffold, Arizona State University scientists, in collaboration with colleagues at the University of Michigan, have developed a 3-D artificial enzyme cascade that mimics an important biochemical pathway that could prove important for future biomedical and energy applications.

26 May 2014

Consistent glycaemic control wards off diabetic complications

Variability in glycaemic control is associated with both microvascular and macrovascular events in patients with Type 2 diabetes, shows an analysis of the ADVANCE trial.

23 May 2014

European Commission grants Marketing Authorization for empagliflozin for treatment of type 2 diabetes

The European Commission has granted Marketing Authorisation for empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor from Boehringer Ingelheim and Eli Lilly and Company.

23 May 2014

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers at the University of Maryland School of Medicine have identified a mutation in a fat-storage gene that appears to increase the risk for type 2 diabetes and other metabolic disorders, according to a study published online today in the New England Journal of Medicine.

23 May 2014

American Association of Diabetes Educators suggests tips for safe travel

AAA estimates 36.1 million people will travel this Memorial Day weekend. If diabetes is your constant companion, that doesn't mean you can't enjoy traveling, whether traversing America in an RV or flying to the far reaches of the globe. Ensuring you stay healthy and keep your glucose levels on an even keel does require a little bit of organization and planning ahead, though.

23 May 2014

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar.

23 May 2014

Researchers develop set of tools that may help diabetic patients and their docs to manage condition

Diabetes affects around 10% of the population; according to the World Health Organisation (WHO). The disease places a huge financial burden on healthcare systems, and also leads to early death and poor quality of life. However, patients and healthcare professionals will now be able to partner up and manage the illness in better, more effective ways.

22 May 2014

Supermodel mouse reveals critical role played by unknown gene that regulates metabolism

A lean "Supermodel" mouse type has revealed the potentially critical role played by a largely unknown gene that regulates metabolism, findings that could provide new insight into diseases ranging from diabetes to obesity, a new study by UT-Southwestern Medical Center researchers suggests.

21 May 2014

Physical activity may be able to prevent overweight women from developing heart disease

For otherwise healthy middle-aged women who are overweight or obese, physical activity may be their best option for avoiding heart disease, according to a study that followed nearly 900 women for seven years.

21 May 2014

New method for identifying bacteria in patient specimens leads to 92% cost reduction

Researchers at UNC Health Care have found that using a new method for identifying bacteria and fungi in patient specimens led to a 92 percent cost reduction in the reagents needed to run clinical microbiology tests.

21 May 2014

Intensive insulin has lasting benefits for diabetic MI survivors

Patients with diabetes given intensive insulin treatment following an acute myocardial infarction had improved survival over 20 years of follow-up of the DIGAMI 1 trial, report the investigators.

19 May 2014

Study examines predictors and effects of testosterone therapy

Three new studies examining the predictors, effects and durability of testosterone therapy on men will be presented to reporters at the 109th Annual Scientific Meeting of the American Urological Association (AUA) during a special press conference in the Orange County Convention Center, Orlando, FL on Sunday, May 18 at 2:00 p.m. ET.

19 May 2014

Data from phase III trials supports safety, efficacy of linagliptin in treating T2D in African-American adults

Data from a retrospective pooled analysis of eight phase III trials (two 18-week and six 24-week) of linagliptin 5 mg once-daily, showed reductions from baseline A1c at 18 (eight trials) and 24 (six trials) weeks compared to placebo in African-American adults with type 2 diabetes (T2D),

16 May 2014

Transition Therapeutics begins TT-401 Phase 2 clinical study for treatment of type 2 diabetes

Transition Therapeutics Inc. today announced the dosing of the first patient in a Phase 2 clinical study of TT-401 (LY2944876), a drug candidate for the treatment of type 2 diabetes.

15 May 2014

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Isis Pharmaceuticals, Inc. announced today positive data from a Phase 2 study of ISIS-GCGRRx in patients with type 2 diabetes uncontrolled on stable metformin therapy.

14 May 2014

Intensive insulin treatment improves survival for diabetic heart attack patients

Long-term follow-up of the DIGAMI 1 trial – a landmark study of type 2 diabetes in Sweden – shows that intensive insulin treatment prolonged life by more than 2 years in patients with diabetes after a heart attack, compared with standard treatment for diabetes, reports Dr Viveca Ritsinger from the Unit of Cardiology of the Department of Medicine, Karolinska Institute, Stockholm, Sweden and colleagues in The Lancet Diabetes & Endocrinology.

14 May 2014

SGK1 enzyme, asthma and cancer therapies: an interview with Dr. Jonathan D. Powell, Johns Hopkins Kimmel Cancer Center

SGK1 stands for serum/glucocorticoid-regulated kinase 1. SGK1 is a member of the AGC kinase family, which is a huge family of kinases.

13 May 2014

Study reveals 70% of patients with diabetic retinopathy will develop macular edema

In Mexico, at least 14 million people have developed macular edema due to diabetes (DME), which like retinopathy affects central vision and can lead to blindness if not treated early .

13 May 2014

Researchers use natural molecule to treat type 2 diabetes

Researchers at the Universit- Laval Faculty of Medicine, the Quebec Heart and Lung Institute Research Center, and the Institute of Nutrition and Functional Foods have discovered a natural molecule that could be used to treat insulin resistance and type 2 diabetes.

13 May 2014

5-year survival of diabetic kidney transplant patients now on par with nondiabetic recipients

Mayo Clinic researchers have discovered that the five-year survival of diabetic kidney transplant patients is now on par with the five-year survival of nondiabetic kidney recipients.

9 May 2014

Glucose News and Research

Scientists develop 3-D artificial enzyme cascade that mimics biochemical pathway using DNA molecules

Consistent glycaemic control wards off diabetic complications

European Commission grants Marketing Authorization for empagliflozin for treatment of type 2 diabetes

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

American Association of Diabetes Educators suggests tips for safe travel

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Researchers develop set of tools that may help diabetic patients and their docs to manage condition

Supermodel mouse reveals critical role played by unknown gene that regulates metabolism

Physical activity may be able to prevent overweight women from developing heart disease

New method for identifying bacteria in patient specimens leads to 92% cost reduction

Intensive insulin has lasting benefits for diabetic MI survivors

Study examines predictors and effects of testosterone therapy

Data from phase III trials supports safety, efficacy of linagliptin in treating T2D in African-American adults

Transition Therapeutics begins TT-401 Phase 2 clinical study for treatment of type 2 diabetes

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Intensive insulin treatment improves survival for diabetic heart attack patients

SGK1 enzyme, asthma and cancer therapies: an interview with Dr. Jonathan D. Powell, Johns Hopkins Kimmel Cancer Center

Study reveals 70% of patients with diabetic retinopathy will develop macular edema

Researchers use natural molecule to treat type 2 diabetes

5-year survival of diabetic kidney transplant patients now on par with nondiabetic recipients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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