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PhoreMost and C4XD sign neurodegeneration drug discovery collaboration agreement

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, and C4X Discovery Holdings plc, a pioneering drug discovery company, today announced they have signed a neurodegeneration drug discovery collaboration agreement.

From PhoreMost 25 Jun 2019

New promising approach repairs system of blood vessels following stroke

Following a stroke, antibodies that inhibit the signaling molecule Nogo-A can help repair blood vessels in the affected brain regions.

25 Jun 2019

Metabolomics may be key to identifying diabetes-related kidney disease

Metabolomics, the study of small molecules the body produces during metabolism (metabolites) may be a future key to identifying diabetes-related kidney disease.

24 Jun 2019

Study sheds light on rhodopsin dynamics in the retina

Photoreceptor cells in our eyes can adjust to both weak and strong light levels, but we still don't know exactly how they do it.

24 Jun 2019

Non-classical monocytes directly involved in regulation of immune response

Non-classical monocytes were long thought to play a purely surveillance role in the immune system. With the aid of a novel marker, Ludwig-Maximilians-Universitaet in Munich researchers have now shown that they are directly involved in the regulation of immune response

24 Jun 2019

Switch that decides fate of cells from neural stem cells discovered

Neurons and astrocytes are prominent cell types in the cerebral cortex. Neurons are the primary information processing cells in the brain, whereas astrocytes support and modulate their functions.

24 Jun 2019

Researchers shed light on bacterial fusion linked to Chlamydia’s pathogenicity

Most people know Chlamydia as the venereal disease that can cause infertility if left untreated. But for researchers studying the causative agent, Chlamydia trachomatis, it's a bacteria with intriguing properties.

24 Jun 2019

Introduction of very small RNA molecule promotes heart cell regeneration, study shows

By adulthood, the heart is no longer able to replenish injured or diseased cells. As a result, heart disease or an event like a heart attack can be disastrous, leading to massive cell death and permanent declines in function.

23 Jun 2019

New discovery may explain some forms of stroke

Scientists from the University of Sheffield have discovered a novel behavior of the blood vessels of the brain in zebrafish that may explain some forms of stroke in humans.

23 Jun 2019

Researchers unlock mystery of immunosuppressive drug's biosynthesis

Mycophenolic acid (MPA), discovered in 1893, was the first natural antibiotic to be isolated and crystallized in human history.

22 Jun 2019

MIT engineers devise new way to create nanoemulsions

MIT chemical engineers have devised a new way to create very tiny droplets of one liquid suspended within another liquid, known as nanoemulsions.

21 Jun 2019

New DNA Microscopy Technique Offers Novel Insight into Genomic Information in Cells

Scientists are now able to see inside cells to a genomic level with a newly invented imaging technique called DNA microscopy. Using DNA “bar codes”, DNA microscopy allows scientists to locate a molecule’s position in a sample without using any kind of optics, meaning genomic information can be collected in large amounts.

21 Jun 2019

Scientists develop a stable platform to reprogram scar tissue into healthy heart cells

Every year 790,000 Americans suffer a heart attack, which leaves damaged scar tissue on the heart and limits its ability to beat efficiently.

21 Jun 2019

Sortilin protein plays crucial role in pain development

Sortilin, which is a protein expressed on the surface of nerve cells, plays a crucial role in pain development in laboratory mice - and in all likelihood in humans as well.

21 Jun 2019

Researchers report new way for creating tracers used with medical imaging

In an advance for medical imaging, scientists from University of North Carolina Lineberger Comprehensive Cancer Center have discovered a method for creating radioactive tracers to better track pharmaceuticals in the body as well as image diseases, such as cancer, and other medical conditions.

21 Jun 2019

Suppressing amygdala molecule enables faster recovery from PTSD symptoms

Fight or flight, panic, trembling: Our brains are wired to ensure we respond instantly to fear. While that fear response may save our lives in the dangerous moment, at times people stay on high alert long after the threat has passed, and develop post-traumatic stress disorder.

20 Jun 2019

Researchers identify genes linked with survival in children with biliary atresia

Scientists at Cincinnati Children's Hospital Medical Center have identified an expression pattern of 14 genes at the time of diagnosis that predicts two year, transplant-free survival in children with biliary atresia – the most common diagnosis leading to liver transplants in children.

19 Jun 2019