Biochemistry News and Research

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Innovative sensing tool used to investigate adenosine triposphate release and its role in cystic fibrosis

The ATP study marks the first application of a novel sensing system developed by a research team led by Christine Kranz at the Georgia Institute of Technology.

27 Mar 2006

Zinc's role in Alzheimer's disease

Zinc may be a familiar dietary supplement to millions of health-conscious people, but it remains a mystery metal to scientists who study zinc's role in Alzheimer's disease, stroke and other health problems.

23 Mar 2006

Researchers gain better understanding of protein folding

Proteins, one of the basic components of living things, are among the most studied molecules in biochemistry. Understanding how proteins form or "fold" from sequenced strings of amino acids has long been one of the grand challenges of biology.

23 Mar 2006

Crucial breakthrough in pectin biosynthesis

Most people know pectin as a common household gelling agent in making jams and jellies, but its uses are vast. It has anticancer properties, for instance, and may have a role in important biological functions including plant growth and development and defense against disease.

22 Mar 2006

Discovery of basic defect in cystic fibrosis airway glands

Scientists at Stanford University have determined that the buildup of sticky mucus found in cystic fibrosis is caused by a loss in the epithelial cell's ability to secrete fluid.

21 Mar 2006

Salmonella research provides clues to antibiotic development

Pathogens are becoming increasingly resistant to antibiotics, causing problems for therapy. Doctors need to have antibiotics available that work in new kinds of ways.

19 Mar 2006

Profound alterations in the brain mechanisms that regulate motivated behavior with addiction

Rats that have a strong craving for cocaine have a different biochemical response to the drug than their less-addicted counterparts, researchers at UT Southwestern Medical Center have found.

15 Mar 2006

Best seller Lipitor shown to improve kidney function

According to drug maker Pfizer it's top selling product worldwide, the cholesterol lowering medication Lipitor (Atorvastatin) has been shown to improve kidney function in patients with heart disease.

13 Mar 2006

Researchers synthesize nisin in a test tube

Scientists have made nisin, a natural antibiotic used for more than 40 years to preserve food, in a test tube for the first time using nature's toolbox.

13 Mar 2006

Nebivolol may restore damaged cardiovascular functions in African Americans

Tadeusz Malinski, Marvin & Ann Dilley White Professor of Chemistry and Biochemistry, found that the drug, currently under review by the U.S. Food and Drug Administration, acts on the level of oxidants lining the cardiovascular system and can restore levels of nitric oxide and reduce oxidative stress.

9 Mar 2006

Scientists create a mosquito resistant to Type 2 dengue fever virus

Researchers have successfully created a genetically engineered mosquito that shows a high level of resistance against the most prevalent type of dengue fever virus, providing a powerful weapon against a disease that infects 50 million people each year.

9 Mar 2006

Details of protein-cleaving complex key to microbe's survival may improve drug design

With the hope of designing more effective treatments for tuberculosis (TB), scientists from the U.S. Department of Energy's Brookhaven National Laboratory and collaborating institutions have published the first detailed reports on the biochemistry and structure of a protein-cleaving complex that is essential to the TB bacterium's survival.

9 Mar 2006

Sex chromosome genes influence aggression

It has been well documented that, across human cultures and in most mammals, males are usually more aggressive and less nurturing than females.

9 Mar 2006

Study looks at how two forms of vitamin E affect the health of animal cells

One of the most powerful antioxidants is truly a double-edged sword, say researchers at Ohio State University who studied how two forms of vitamin E act once they are inside animal cells.

7 Mar 2006

Simple saliva test may offer a new way to probe the consequences of caffeine coupled with stress

Using doses of caffeine equivalent to drinking one to four cups of coffee and an intense arithmetic test as stressors, Klein and her colleagues found a rise in the amount of alpha amylase, an enzyme secreted by the salivary glands, in the healthy young men who participated in the study.

7 Mar 2006

Research shows promise for the advancement of cancer and stem-cell research

The paper explains how proteins, known as epigenetic activators (such as Ash1 from the fruit fly Drosophila), bind to their target DNA and activate genes that determine what function a cell will have in the body.

1 Mar 2006

Hand-held device for detecting illegal and legal drugs

A real-time sensor for detecting cocaine - made with inexpensive, off-the-shelf electronics - has been developed by a team of researchers at the University of California, Santa Barbara.

1 Mar 2006

New mechanism that regulates K-Ras - protein that plays an important role in cancer

Researchers have discovered a protein widely known to cause the out-of-control growth of cells can actually be manipulated to induce those cells to commit suicide, providing a novel target for the development of anti-cancer drugs, according to the results of a new study led by New York University School of Medicine researchers.

21 Feb 2006

New system for analyzing how drugs bind to proteins

Researchers at Florida State University's National High Magnetic Field Laboratory and Scripps Florida have developed and evaluated a robust new system for analyzing how drugs bind to proteins. This groundbreaking work could speed the delivery of potential new drugs and improve existing ones.

19 Feb 2006

Research suggests that a common mechanism may underlie a variety of protein folding diseases

Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.

16 Feb 2006