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Alcohol-linked disease overtakes hep C as top reason for liver transplant

An estimated 17,000 Americans are on the waiting list for a liver transplant, and there's a strong chance that many of them have alcohol-associated liver disease. ALD now edges out hepatitis C as the No. 1 reason for liver transplants in the United States, according to research published Tuesday in JAMA Internal Medicine.

23 Jan 2019

New drug for treating liver parasites in vivax malaria

Vivax malaria is a serious illness with high fever that, if untreated, can keep people bed-ridden for weeks or even months. But even after successful treatment, it's tricky: although the current, commonly-used drugs successfully treat the blood stage of vivax malaria, they are unable to prevent malaria parasites from invading the liver (liver stage) and causing the disease to recur repeatedly over many years.

21 Jan 2019

Branched-chain amino acids in tumors can be targeted to prevent and treat cancer

Researchers at A*STAR's Singapore Bioimaging Consortium have discovered that branched-chain amino acids in tumors can be targeted to prevent and treat cancer. Together with collaborators from the United States and National Cancer Centre Singapore, they found that some cancers potently suppress the catabolism (breakdown) of BCAAs.

21 Jan 2019

Placenta adapts and compensates when pregnant mothers have poor diets or low oxygen

Cambridge researchers have discovered the placenta regulates how much oxygen and nutrients it transports to babies during challenging pregnancies in a study using mice to model conditions in the womb.

21 Jan 2019

UNIST researcher named as recipient of Merck’s 2018 Life Science Awards

Jun Ho Lee, a doctroral student in Life Sciences at UNIST, has been named as a recipient of Merck's 2018 Life Science Awards in Tumor Biology, receiving the grand prize of $10,000.

21 Jan 2019

Study shows hereditary hemochromatosis behind many cancers and joint diseases

A British study has found that “stealth disease”, also known as hemochromatosis, could be the reason behind several disease conditions including cancers and joint diseases.

20 Jan 2019

Hepatitis C-infected patients with a history of liver cancer can be treated with antivirals

A large, multi-center study refutes earlier suggestions that antiviral drugs for treating hepatitis C may lead to a higher recurrence of liver cancer.

18 Jan 2019

Researchers identify new therapeutic target in the fight against chronic liver diseases

Chronic liver disease is known as the silent killer, as it shows no obvious symptoms until the disease has progressed to an advanced stage. Therefore, making a proper diagnosis in the early stage of disease progression can be a clinical challenge.

18 Jan 2019

Many cancer patients have undiagnosed hepatitis

A new report has described an alarmingly high rate of undiagnosed acute and chronic hepatitis B and hepatitis C in patients with cancer.

17 Jan 2019

Study reveals potential pathway for endothelial cells to avoid apoptosis

Cell death is an important aspect of tissue homeostasis, as well as inflammation and disease pathogenesis related to infection, injury, and tumor growth.

17 Jan 2019

Preparation, characterization of Soyasapogenol B loaded onto functionalized MWCNTs

Multi-Walled Carbon Nanotubes is the name that is derived from their structure and walls are formed by one atom thick sheet of carbon.

17 Jan 2019

Cellular protein that interacts with viruses appears to enable infection process of Zika virus

A cellular protein that interacts with invading viruses appears to help enable the infection process of the Zika virus, according to an international team of researchers who suggest this protein could be a key target in developing new therapies to prevent or treat Zika virus infection.

17 Jan 2019

Salk team uses new model to study health effects of AMP-activated protein kinase

The metabolic protein AMPK has been described as a kind of magic bullet for health. Studies in animal models have shown that compounds that activate the protein have health-promoting effects to reverse diabetes, improve cardiovascular health, treat mitochondrial disease--even extend life span.

16 Jan 2019

Researchers reveal how fasting leads to better overall health

In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases.

16 Jan 2019

Researchers use gene-editing tool CRISPR/Cas9 to limit impact of parasitic diseases

For the first time, researchers at the George Washington University, together with colleagues at institutes in Thailand, Australia, the U.K. and the Netherlands, and more, have successfully used the gene-editing tool CRISPR/Cas9 to limit the impact of parasitic worms responsible for schistosomiasis and for liver fluke infection, which can cause a diverse spectrum of human disease including bile duct cancer.

16 Jan 2019

Researchers identify MANF as a rejuvenating factor in parabiosis

Older mice who are surgically joined with young mice in order to share a common bloodstream get stronger and healthier, making parabiosis one of the hottest topics in age research. Publishing in Nature Metabolism, researchers from the Buck Institute report that MANF (mesencephalic astrocyte-derived neurotrophic factor) is one of the factors responsible for rejuvenating the transfused older mice.

16 Jan 2019

Study analyzes vaccine-preventable infections in children who receive solid organ transplants

Children who receive solid organ transplants are hospitalized due to vaccine-preventable infections at rates that are significantly higher than the general population, according to a newly published study by University of Colorado School of Medicine researchers.

15 Jan 2019

Novel microfluidic device for real-time detection of cholesterol in liver-on-chip cultures

In a paper to be published in the September/December 2019 issue of TECHNOLOGY, a team of researchers from the Department of Biomedical Engineering at Illinois Institute of Technology, Chicago has developed a novel microfluidic device for measuring in real-time the cholesterol secreted from liver tissue-chip containing human hepatocytes.

11 Jan 2019

Excess belly fat may lead to a reduction in gray matter

A new study has found that excess abdominal fat is associated with a lower volume of gray matter in the brain, resulting in a smaller brain size.

11 Jan 2019

Research suggests possible way to improve survival in African-Americans undergoing liver transplant

Among African-American adults undergoing liver transplant to treat liver cancer, patients whose organ donor was also African-American lived significantly longer than those with a racially unmatched donor, report authors of a new study using national data.

10 Jan 2019

Liver News and Research

Alcohol-linked disease overtakes hep C as top reason for liver transplant

New drug for treating liver parasites in vivax malaria

Branched-chain amino acids in tumors can be targeted to prevent and treat cancer

Placenta adapts and compensates when pregnant mothers have poor diets or low oxygen

UNIST researcher named as recipient of Merck’s 2018 Life Science Awards

Study shows hereditary hemochromatosis behind many cancers and joint diseases

Hepatitis C-infected patients with a history of liver cancer can be treated with antivirals

Researchers identify new therapeutic target in the fight against chronic liver diseases

Many cancer patients have undiagnosed hepatitis

Study reveals potential pathway for endothelial cells to avoid apoptosis

Preparation, characterization of Soyasapogenol B loaded onto functionalized MWCNTs

Cellular protein that interacts with viruses appears to enable infection process of Zika virus

Salk team uses new model to study health effects of AMP-activated protein kinase

Researchers reveal how fasting leads to better overall health

Researchers use gene-editing tool CRISPR/Cas9 to limit impact of parasitic diseases

Researchers identify MANF as a rejuvenating factor in parabiosis

Study analyzes vaccine-preventable infections in children who receive solid organ transplants

Novel microfluidic device for real-time detection of cholesterol in liver-on-chip cultures

Excess belly fat may lead to a reduction in gray matter

Research suggests possible way to improve survival in African-Americans undergoing liver transplant

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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