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Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

Dengue virus infects about 400 million people annually around the world, with a high prevalence in tropical and sub-tropical regions.

20 Sep 2019

Study confirms lasting impact of neonatal CPAP technology in Malawi

Malawi's national adoption of affordable, rugged, neonatal CPAP technology as a part of routine hospital care resulted in sustained improvements in the survival of babies with respiratory illness, according to a new study in the journal Pediatrics.

20 Sep 2019

Penn researchers develop novel vaccine to protect against genital herpes

Researchers from the Perelman School of Medicine at the University of Pennsylvania have developed a vaccine to protect against genital herpes.

20 Sep 2019

UMSOM receives landmark contract from NIAID for influenza research

Kathleen Neuzil, MD, MPH, Professor of Medicine and Pediatrics and Director of the Center for Vaccine Development and Global Health at the University of Maryland School of Medicine and Dean E. Albert Reece, MD, PhD, MBA, announced that CVD has been awarded a contract from the National Institute of Allergy and Infectious Diseases, with total funding up to more than $200 million over seven years if all contract options are exercised.

20 Sep 2019

Discovery of combination protein leads to first-in-human clinical trial for leukemia

The discovery of tri-specific natural killer engagers (TriKE™), a combination protein that bridges an immune cell and a tumor cell to drive tumor cell killing power exponentially, has led to a new Phase I, first-in-human study to treat leukemia.

20 Sep 2019

Scientists link neuropsychological tests with real-life activity in MS patients

A recent review by Kessler Foundation researchers explored the relationship between neuropsychological assessment and predictability of performance of everyday life activities among people with multiple sclerosis (MS).

20 Sep 2019

Genetics may predispose some diabetic patients to develop kidney disease

In an unprecedented scale, researchers have begun to unravel the genetics that may predispose some individuals to develop kidney disease once they have diabetes, independent of the degree of blood sugar control.

20 Sep 2019

People with persistent back pain, headaches twice as likely to suffer from both disorders

People with persistent back pain or persistent headaches are twice as likely to suffer from both disorders, a new study from the University of Warwick has revealed.

20 Sep 2019

AAD honors dermatologist for her role in treating a patient with rare skin disease

The American Academy of Dermatology has honored board-certified dermatologist Karen Wiss, MD, FAAD, as a Patient Care Hero for her role in treating a patient born with an extremely rare skin disease caused by a genetic mutation.

19 Sep 2019

Study uncovers new factor in the development of childhood lymphoma

A study recently published in the renowned journal Blood, led by Kaan Boztug, Scientific Director of the St. Anna Children's Cancer Research Institute, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Adjunct Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Associate Professor at the Medical University of Vienna, together with scientists from Israel, Germany, Turkey, Colombia, Argentina and the USA, investigated four patients from independent families with malignancy, autoimmunity and immunodeficiency.

19 Sep 2019

Microrna-based therapy may prove to be effective against chemotherapy-resistant cancers

A technology that manipulates microRNAs developed by Jingfang Ju, PhD, a biochemist and Professor in the Department of Pathology at the Renaissance School of Medicine at Stony Brook University, and colleagues has shown promise when used as anti-cancer therapeutic.

19 Sep 2019

Explosion at biofacility in Russia raises concerns over safety: Should we be worried?

A Russian research facility which holds one of the world's largest collections of viruses has suffered an explosion, triggering concerns over potential biological contamination.

18 Sep 2019

Sleep studies may be an unreliable predictor for treatment of children with sleep apnea

Pediatricians routinely advise parents of children who snore regularly and have sleepiness, fatigue or other symptoms consistent with sleep disordered breathing, to get a sleep study; this can help determine whether their child has obstructive sleep apnea, which is often treated with surgery to remove the tonsils and adenoids (adenotonsillectomy).

18 Sep 2019

Gut microbiome may play a role in mechanisms linked to muscle strength in older adults

A novel new study suggests that the gut microbiome has a role in mechanisms related to muscle strength in older adults.

18 Sep 2019

Study examines racial disparities in survival outcomes of pediatric patients with Hodgkin lymphoma

In what is believed to be the largest dataset study to date examining the role of race on survival outcome for pediatric patients with Hodgkin lymphoma, investigators at Rutgers Cancer Institute of New Jersey have found that black patients have significantly worse overall survival at five years than white patients when accounting for all available clinical variables.

18 Sep 2019

Patients with non-Hodgkin's lymphoma may benefit from radiation, experience reduced side effects

Treating non-Hodgkin's lymphoma patients with radiation therapy as an additional treatment while they wait for their CAR T cells to be manufactured may reduce the risk of CAR T therapy side effects once it is administered, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania.

18 Sep 2019

Text messaging, electric pill bottles not enough to drive down blood pressure levels

About one in three Americans have high blood pressure, called hypertension, but only about half of them have their condition under control.

18 Sep 2019

Rutgers cardiologist recommends individualized treatment with aspirin for primary prevention of CVD

A nationally recognized Rutgers cardiologist recommends that aspirin be used as primary prevention for cardiovascular disease only with select patients, saying that the scientific evidence is too diverse to support a one-size-fits-all approach.

17 Sep 2019

Improving care and educational outreach for lupus patients

A new grant will allow MUSC doctors and researchers to test several ideas for improving care and outreach to people with lupus or at risk of developing the autoimmune disease.

17 Sep 2019

New results revealed from pilot stem cell study for stroke

Researchers led by Sean I. Savitz, MD, reported today in the journal Stem Cells that bone marrow cells used to treat ischemic stroke in an expanded Phase I trial were not only safe and feasible, but also resulted in enhanced recovery compared to a matched historical control group.

17 Sep 2019

Medical School News and Research

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

Study confirms lasting impact of neonatal CPAP technology in Malawi

Penn researchers develop novel vaccine to protect against genital herpes

UMSOM receives landmark contract from NIAID for influenza research

Discovery of combination protein leads to first-in-human clinical trial for leukemia

Scientists link neuropsychological tests with real-life activity in MS patients

Genetics may predispose some diabetic patients to develop kidney disease

People with persistent back pain, headaches twice as likely to suffer from both disorders

AAD honors dermatologist for her role in treating a patient with rare skin disease

Study uncovers new factor in the development of childhood lymphoma

Microrna-based therapy may prove to be effective against chemotherapy-resistant cancers

Explosion at biofacility in Russia raises concerns over safety: Should we be worried?

Sleep studies may be an unreliable predictor for treatment of children with sleep apnea

Gut microbiome may play a role in mechanisms linked to muscle strength in older adults

Study examines racial disparities in survival outcomes of pediatric patients with Hodgkin lymphoma

Patients with non-Hodgkin's lymphoma may benefit from radiation, experience reduced side effects

Text messaging, electric pill bottles not enough to drive down blood pressure levels

Rutgers cardiologist recommends individualized treatment with aspirin for primary prevention of CVD

Improving care and educational outreach for lupus patients

New results revealed from pilot stem cell study for stroke

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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