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Large ALS-causing protein aggregates protect rather than harm neurons

Scientists at the UNC School of Medicine have made a significant advance in the understanding of the complex and fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

17 Apr 2018

Research sheds light on links between brain growth and post-natal sensory experiences

New research by University of Toronto neuroscientists sheds light on links between early brain growth and sensations experienced by animals soon after birth.

16 Apr 2018

Novel disease model for ALS and MS can be used to develop new immunotherapies

Researchers at Karolinska Institutet in Sweden have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. The model is described in a publication in the scientific journal Nature Immunology.

16 Apr 2018

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Amyotrophic lateral sclerosis is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS.

16 Apr 2018

New method could help treat severe epilepsy in the future

Researchers at Lund University in Sweden believe they have found a method that in the future could help people suffering from epilepsy so severe that all current treatment is ineffective.

16 Apr 2018

Sleep deprivation increases brain protein linked to Alzheimer's disease

Losing just one night of sleep led to an immediate increase in beta-amyloid, a protein in the brain associated with Alzheimer's disease, according to a small, new study by researchers at the National Institutes of Health. In Alzheimer's disease, beta-amyloid proteins clump together to form amyloid plaques, a hallmark of the disease.

13 Apr 2018

Two MDC researchers win ERC funding worth several million euros

Basic researchers Gary Lewin and Norbert Hübner are investigating the molecular mechanisms underlying neurological and heart diseases. Their focus is on understanding the anchoring of ion channels and micropeptides in heart muscle cells.

13 Apr 2018

Protein linked with Alzheimer's disease affects different brain cells differently

Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies.

13 Apr 2018

Glucose metabolism is key to neural network development, finds study

A new study has found that glucose metabolism is critical for the development of neural networks in the brain.

13 Apr 2018

People with rare dementia may employ intact brain areas for help with language

People with a rare dementia that initially attacks the language center of the brain recruit other areas of the brain to decipher sentences, according to new research led by a University of Arizona cognitive scientist.

12 Apr 2018

Aberrant protein prevents self-cleaning of nerve cells in ALS

Scientists have discovered that TDP-43 interferes with lysosomal pathways responsible for its clearance and induces autophagy in ALS.

12 Apr 2018

Researchers develop thin, flexible polymers to record activity more deeply in the brain

Science has yet to unravel a complete understanding of the brain and all its intricate workings. It's not for lack of effort.

11 Apr 2018

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Scientists at the University of Wyoming have found that mice engineered to have Huntington's disease (HD) have an over-accumulation of iron in their mitochondria.

11 Apr 2018

The brain fights neurodegenerative diseases by shifting resources

The brain continues to put up a fight even as neurodegenerative diseases like dementia damage certain areas and functions. In fact, recent findings in a Baycrest-University of Arizona study suggest that one method the brain uses to counter these diseases is the reassigning of tasks to different regions.

11 Apr 2018

Johns Hopkins researchers wirelessly record brain activity of free-moving bats

Johns Hopkins University researchers have developed a way to study the brain of a bat as it flies, recording for the first time what happens as a roving animal focuses and refocuses its attention.

11 Apr 2018

Biomarker panel can guide future therapeutic decisions for glioma patients

In an article published April 10th in the journal Cell Reports, researchers at the University of São Paulo describe a biomarker panel that could tell physicians which patients diagnosed with glioma, a type of brain cancer, will tend to progress to a more aggressive form of the disease in the event of relapse.

10 Apr 2018

Japanese researchers develop new compound to enhance recovery of stroke patients

A team of Japanese researchers have developed a new compound that enhanced motor function recovery after brain damage in animal tests, according to a study published in the journal Science.

10 Apr 2018

Houston Methodist-led research focuses on rare, inherited neurodegenerative disorder

A rare, inherited neurodegenerative disorder will soon be the focus of an international clinical research effort led by Houston Methodist and funded by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

10 Apr 2018

New research sheds light on how neurons in the brain communicate with one another

Researchers from the University of Leicester have shed new light on how neurons in the brain communicate with one another. This could potentially help in our understanding of how and why a range of neurodegenerative diseases occur.

10 Apr 2018

Validating the Diagnosis of Depression

It’s very difficult to diagnose depression. With depression, you can't open the brain to find answers, and the chemistry of the brain is separate from the chemistry of the body.

From Pittcon 10 Apr 2018