Immune System News and Research

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Patients with obesity at greater risk of developing long-term complications of COVID-19

A Cleveland Clinic study shows that survivors of COVID-19 who have moderate or severe obesity may have a greater risk of experiencing long-term consequences of the disease, compared with patients who do not have obesity.

3 Jun 2021

SARS-CoV-2 exploits metal-dependent mechanism to evade immune surveillance

Scientists from The University of Texas Health Science Center at San Antonio have discovered a mechanism by which SARS-CoV-2 exploits changes in metal ion concentrations to disguise itself in the body. Varying concentrations of metal ions -- positively charged atoms such as magnesium, manganese and calcium -- are observed in hospitalized COVID-19 patients.

3 Jun 2021

Researchers are closer to unraveling the mystery of science behind regeneration

Many salamanders can readily regenerate a lost limb, but adult mammals, including humans, cannot. Why this is the case is a scientific mystery that has fascinated observers of the natural world for thousands of years.

3 Jun 2021

NCI grants more than $4.2 million to launch Cancer Epitope Database and Analysis Resource

Researchers are about to welcome a new one-stop shop for crucial information on how the immune system targets cancers.

3 Jun 2021

Newly developed spheroidal structure reproduces the microenvironment of tumors

Every tumor is different, every patient is different. So how do we know which treatment will work best for the patient and eradicate the cancer? In order to offer a personalised treatment that best suits the case being treated, a team of scientists led by the University of Geneva (UNIGE), Switzerland, had already developed a spheroidal reproduction of tumors that integrates the tumor cells, but also their microenvironment.

3 Jun 2021

Tiny implant reverses diabetes in mice without requiring drugs

A team of researchers led by diabetes specialists and biomedical engineers at Washington University School of Medicine in St. Louis and Cornell University has demonstrated that, using a miniscule device, they can implant insulin-secreting cells into diabetic mice.

3 Jun 2021

People taking anti-inflammatory drug mount a weaker immune response to COVID-19 vaccine

One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows.

2 Jun 2021

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

A new bioRxiv* preprint reports on the successful use of a protocol to expand SARS-CoV-2-reactive T-cells a thousand-fold.

2 Jun 2021

Newly identified protein could become a target for future cancer treatments

Researchers at the Francis Crick Institute have identified a protein that helps tumours evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments.

2 Jun 2021

New insight into how platelets help resolve bacterial lung inflammation

Treating patients with acute respiratory failure is a constant challenge in intensive care medicine. In most cases, the underlying cause is lung inflammation triggered by a bacterial infection or - more rarely, despite being frequently observed at present due to the corona pandemic - a viral infection.

2 Jun 2021

Coronavirus strain associated with dogs found in humans

Coronavirus strain associated with dogs found in swabs taken from pneumonia patients in Malaysia.

2 Jun 2021

Natural Killer cells acts as a potential target of immunotherapy, shows study

Despite a name straight from a Tarantino movie, natural killer (NK) cells are your allies when it comes to fighting infections and cancer.

2 Jun 2021

Old vaccines can stimulate the immune system to provide protection against other infectious diseases

Inoculation with live attenuated vaccines (LAV) such as those used against TB, polio or measles can stimulate the immune system to provide protection against other infectious diseases, including COVID-19, says a new study.

2 Jun 2021

Researchers find natural metabolites help SARS-CoV-2 escape antibodies

An international team of scientists has identified a human molecule — biliverdin — as a potential severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) target. The binding of the heme metabolite to the N-terminal domain of SARS-CoV-2 is associated with the virus’s ability to dodge the immune system by suppressing antibody binding to the spike protein.

2 Jun 2021

Direct action of SARS-CoV-2 on organs may lead to exacerbated inflammatory response in pediatric patients

Besides common symptoms such as fever, cough and respiratory distress, some children have an atypical form of COVID-19 known as multisystem inflammatory syndrome in children (MIS-C), characterized by persistent fever and inflammation of several organs, such as the heart and intestines, as well as the lungs to a lesser extent.

1 Jun 2021

NIH launches first-in-human, Phase 1 trial assessing investigational nanoparticle influenza vaccine

A first-in-human, Phase 1 trial assessing the safety and immunogenicity of an investigational nanoparticle influenza vaccine designed to provide long-lasting protection against multiple flu virus strains has begun at the National Institutes of Health Clinical Center in Bethesda, Maryland.

1 Jun 2021

Scientists explain possible causes of anaphylaxis following mRNA COVID-19 vaccination

New research from a team of scientists at the Centre for Research in Molecular Modeling, Department of Chemistry and Biochemistry, Concordia University in Canada, has aimed to determine the potential causes of anaphylaxis or allergic reactions reported in some individuals after receiving COVID-19 vaccines, including the mRNA vaccines by Pfizer-BioNTech and Moderna.

1 Jun 2021

Moffitt Cancer Center presents new data from dozens of clinical research studies at ASCO

Moffitt Cancer Center, a national leader in cancer care and research and the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, is presenting new data from dozens of clinical research studies at this year's American Society of Clinical Oncology (ASCO) Annual Meeting, the world's largest clinical cancer research meeting.

1 Jun 2021

Study reveals infections by Histoplasma fungus as major cause of death in people with HIV

A series of autopsies performed in an infectious disease hospital in the Brazilian Amazon reveals that infections by the Histoplasma fungus are a major cause of death in people with HIV.

1 Jun 2021

Little-known illnesses turning up in Covid long-haulers

The day Dr. Elizabeth Dawson was diagnosed with covid-19 in October, she awoke feeling as if she had a bad hangover. Four months later she tested negative for the virus, but her symptoms have only worsened.

1 Jun 2021

Immune System News and Research

Patients with obesity at greater risk of developing long-term complications of COVID-19

SARS-CoV-2 exploits metal-dependent mechanism to evade immune surveillance

Researchers are closer to unraveling the mystery of science behind regeneration

NCI grants more than $4.2 million to launch Cancer Epitope Database and Analysis Resource

Newly developed spheroidal structure reproduces the microenvironment of tumors

Tiny implant reverses diabetes in mice without requiring drugs

People taking anti-inflammatory drug mount a weaker immune response to COVID-19 vaccine

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

Newly identified protein could become a target for future cancer treatments

New insight into how platelets help resolve bacterial lung inflammation

Coronavirus strain associated with dogs found in humans

Natural Killer cells acts as a potential target of immunotherapy, shows study

Old vaccines can stimulate the immune system to provide protection against other infectious diseases

Researchers find natural metabolites help SARS-CoV-2 escape antibodies

Direct action of SARS-CoV-2 on organs may lead to exacerbated inflammatory response in pediatric patients

NIH launches first-in-human, Phase 1 trial assessing investigational nanoparticle influenza vaccine

Scientists explain possible causes of anaphylaxis following mRNA COVID-19 vaccination

Moffitt Cancer Center presents new data from dozens of clinical research studies at ASCO

Study reveals infections by Histoplasma fungus as major cause of death in people with HIV

Little-known illnesses turning up in Covid long-haulers

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