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Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders.

23 Oct 2022

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Researchers explore whether FebriDx could differentiate between bacteria- and virus-induced immune responses during acute respiratory infection.

23 Oct 2022

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Researchers examine neutralizing antibody responses against SARS-CoV-2 in elderly individuals who received one mRNA booster dose.

23 Oct 2022

How does COVID-19 and its treatment affect testicular function?

Researchers summarized available information related to the reproductive effects of COVID-19 in men.

23 Oct 2022

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Researchers performed retrospective detection of the monkeypox virus in the testes of nonhuman primates.

22 Oct 2022

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil suggest that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits SARS-CoV-2 replication as well as the exacerbated inflammatory response that leads to death in many patients with severe COVID-19.

21 Oct 2022

Scientists receive $8.297 NIH grant to continue funding a Center for Lupus Research

A multi-institutional team of scientists, led by researchers at Weill Cornell Medicine's Gale and Ira Drukier Institute for Children's Health, have received a five-year $8.297 grant to continue funding a Center for Lupus Research.

21 Oct 2022

Modeling study suggests the possibility of Japanese encephalitis virus outbreak in Australia

A paper from a research team, which included mathematical modeling expertise from LSHTM and was led by the QIMR Berghofer Medical Research Institute in Brisbane, has suggested that up to 750,000 people across Australia could be at risk of exposure to Japanese encephalitis (JEV).

21 Oct 2022

Exploring SARS-CoV-2-associated endothelial dysfunction

A new study described the evidence, mechanisms, and therapies for endothelial dysfunction in coronavirus disease 2019 (COVID-19).

21 Oct 2022

Multiple research platforms identify environmental chemical agents that promote intestinal inflammation

Inflammatory bowel disease (IBD), a condition characterized by chronic gastrointestinal inflammation, is becoming increasingly common in industrialized countries.

21 Oct 2022

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

In a recent study posted to the medRxiv* preprint server, University of Arizona researchers assessed the relationship between antibody responses and analgesic usage after coronavirus disease 2019 (COVID-19) vaccination.

20 Oct 2022

Two small molecules reverse pancreatic acinar ductal metaplasia

Pancreatic cancer often lurks as a silent disease. With no known symptoms, it can progress undetected and spread to other organs.

20 Oct 2022

Licorice root extract shows potential as a COVID-19 treatment

A recent study explores the activity of glycyrrhizin against SARS-CoV-2.

19 Oct 2022

Mass General Brigham sites announce participation in phase 3 trial of monkeypox treatment

Massachusetts General Hospital and Brigham and Women's Hospital, the founding members of Mass General Brigham, today announced their participation in STOMP (Study of Tecovirimat for Human Monkeypox Virus), a phase 3, randomized, placebo-controlled, double-blind trial evaluating the safety and efficacy of tecovirimat (TPOXX) for the treatment of human monkeypox.

19 Oct 2022

SARS-CoV-2 virus alters the composition of breast milk, research shows

A research team from the University of Huelva in collaboration with the MilkCORONA initiative has demonstrated that the SARS-CoV-2 virus alters the composition of breast milk.

19 Oct 2022

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

According to a recent study, substance P produced by the nociceptors present in the gut lining confers protection against inflammation and tissue damage by increasing the number of beneficial microbes.

19 Oct 2022

Study shows the importance of both obesity and biological sex in COVID-19 outcomes

A new animal study from Katherine Lee, a researcher with the West Virginia University School of Medicine, investigates why individuals with obesity may have a particularly difficult time fending off SARS-CoV-2, the virus that causes COVID-19.

19 Oct 2022

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Researchers discussed the pathophysiological mechanisms of endothelial dysfunction associated with severe coronavirus disease 2019 (COVID-19) and commented on the potential therapeutic strategies to treat endothelial damage and coagulopathy related to COVID-19.

19 Oct 2022

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Researchers examined the role of epigenetic modifications of the host cell gene expression in determining the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and explored the use of vitamin D as a therapeutic agent against coronavirus disease 2019 (COVID-19).

19 Oct 2022

SARS-CoV-2 placentitis may cause placental destruction and stillbirth in women not vaccinated for COVID-19

As compared to healthy women, pregnant women infected with SARS-CoV-2 are at a high risk of fatal clinical outcomes.

18 Oct 2022

Inflammation News and Research

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

How does COVID-19 and its treatment affect testicular function?

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Scientists receive $8.297 NIH grant to continue funding a Center for Lupus Research

Modeling study suggests the possibility of Japanese encephalitis virus outbreak in Australia

Exploring SARS-CoV-2-associated endothelial dysfunction

Multiple research platforms identify environmental chemical agents that promote intestinal inflammation

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

Two small molecules reverse pancreatic acinar ductal metaplasia

Licorice root extract shows potential as a COVID-19 treatment

Mass General Brigham sites announce participation in phase 3 trial of monkeypox treatment

SARS-CoV-2 virus alters the composition of breast milk, research shows

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

Study shows the importance of both obesity and biological sex in COVID-19 outcomes

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

SARS-CoV-2 placentitis may cause placental destruction and stillbirth in women not vaccinated for COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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