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NanoTCE technology shows promise for treatment of acute myeloid leukemia

Oncotarget published "Nanoparticle T cell engagers for the treatment of acute myeloid leukemia" which reported that Acute myeloid leukemia (AML) is the most common type of leukemia and has a 5-year survival rate of 25%.

12 Nov 2021

Higher order protein catenation leads to the development of artificial antibodies

Chemical topology is a unique dimension for protein engineering. Over the past few years, the discovery of topological nontrivial proteins in nature has already revealed their many potential functional benefits, such as enhanced thermal/mechanical/chemical stability.

12 Nov 2021

COVID-19 vaccination humoral immune response in individuals with diabetes

A new study investigated the humoral immune response and side effects related to COVID-19 vaccines in individuals with type 1 diabetes and type 2 diabetes.

12 Nov 2021

Rare disease diagnosis by 100,000 genomes pilot

A team of researchers conducted a pilot study that enrolled families and undertook detailed clinical phenotyping of the proband to evaluate the effect of the whole genome sequencing approach on a genetic diagnosis of rare conditions by the NHS in the UK.

12 Nov 2021

Researchers identify gene expression involved in cancer progression and chemotherapy resistance

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

11 Nov 2021

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

10 Nov 2021

Current understanding of the link between COVID-19 and cardiovascular disease

A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.

10 Nov 2021

Proton therapy used for the first time in Switzerland to treat lung cancer

Today a 60-year-old patient suffering from lung cancer received proton beam therapy, a medical procedure where positively charged particles are precisely targeted at the tumor. This is the first time this type of radiotherapy has been used for lung cancer treatment in Switzerland.

9 Nov 2021

Study explores the impact of ethnicity on brain tumor survival

White British people who have been diagnosed with a malignant primary brain tumor appear to be more likely to die within one year than patients from at least four other ethnic groups according to a study presented at the NCRI Festival.

9 Nov 2021

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Despite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation (ACR/NPF) in 2018, there is limited data regarding medication use in real-world clinical practice and patient medication preferences for the treatment of psoriatic arthritis (PsA).

9 Nov 2021

Researchers identify safety concerns with neuroblastoma candidate drug

St. Jude Children's Research Hospital scientists looking for drugs to improve survival of children with high-risk neuroblastoma found a promising candidate in CX-5461.

9 Nov 2021

Targeting Shp2 in oncological treatments appears to worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

9 Nov 2021

Binghamton professor receives grant to develop a faster, less painful way to diagnose lung nodules

A biomedical engineering professor at Binghamton University, State University of New York has received a $2.4 million grant to develop a faster, less painful way to diagnose malignant solitary pulmonary nodules (SPNs).

9 Nov 2021

Novel study aims to develop personalized treatment for triple-negative breast cancer

Indiana University School of Medicine researcher Bryan P. Schneider, MD, is leading a novel nationwide study to better understand how to treat patients with triple-negative breast cancer based on their own unique genetic data.

8 Nov 2021

Study points to a new, effective treatment option for patients with mesothelioma

Combining the immunotherapy agent durvalumab with the chemotherapy agents pemetrexed and cisplatin or carboplatin may provide a new treatment option for patients who have inoperable pleural mesothelioma, a cancer of the tissues lining the lungs, according to a phase II clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

8 Nov 2021

Study shows how whole genome sequencing could benefit children with cancer

Unravelling the entire genetic code for each child who has been diagnosed with cancer can give a more accurate diagnosis or reveal new treatment options, according to research presented at the NCRI Festival. These are the results of a pilot study of the process known as whole genome sequencing.

8 Nov 2021

Childhood kidney cancers continue to be diagnosed at later stages in the UK and Ireland

Children with kidney cancers continue to be diagnosed with larger and more advanced tumours in the UK and Ireland than in other Western European countries, according to research presented at the NCRI Festival.

8 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Anemia is a common and sometimes debilitating problem among patients with chronic kidney disease (CKD). Anemia can occur when the kidneys become damaged, limiting the production of erythropoietin (EPO) - a hormone that signals to the body to make red blood cells.

7 Nov 2021

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Scientists at the Francis Crick Institute have found how the immune system triggers an 'emergency' dendritic cell response during infection, with dendritic cells at the site of infection being reinforced by new cells which travel from the bone marrow.

6 Nov 2021

Tumor News and Research

NanoTCE technology shows promise for treatment of acute myeloid leukemia

Higher order protein catenation leads to the development of artificial antibodies

COVID-19 vaccination humoral immune response in individuals with diabetes

Rare disease diagnosis by 100,000 genomes pilot

Researchers identify gene expression involved in cancer progression and chemotherapy resistance

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Current understanding of the link between COVID-19 and cardiovascular disease

Proton therapy used for the first time in Switzerland to treat lung cancer

Study explores the impact of ethnicity on brain tumor survival

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Researchers identify safety concerns with neuroblastoma candidate drug

Targeting Shp2 in oncological treatments appears to worsen the disease

Binghamton professor receives grant to develop a faster, less painful way to diagnose lung nodules

Novel study aims to develop personalized treatment for triple-negative breast cancer

Study points to a new, effective treatment option for patients with mesothelioma

Study shows how whole genome sequencing could benefit children with cancer

Childhood kidney cancers continue to be diagnosed at later stages in the UK and Ireland

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Study discovers how the immune system triggers an 'emergency' dendritic cell response during infection

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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