Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Alcohol flush signals increased cancer risk among east Asians

Many people of East Asian descent possess an enzyme deficiency that causes their skin to redden, or flush, when they drink alcohol.

23 Mar 2009

Prostate cancer expert say keep screening in face of contradicting data

New data evaluating the impact of screening on mortality provides mixed messages on the value of prostate cancer screening.

20 Mar 2009

Lung cancer: Molecular scissors determine therapy effectiveness

In the past few years, a number of anti-cancer drugs have been developed which are directed selectively against specific key molecules of tumor cells.

17 Mar 2009

A biomarker test to diagnose or rule out Alzheimer's disease

A test capable of confirming or ruling out Alzheimer's disease has been validated and standardized by researchers at the University of Pennsylvania School of Medicine.

16 Mar 2009

Obesity brings worse outcomes after pancreatic cancer surgery

Obese patients with a body mass index (BMI) of more than 35 appear more likely to have cancer that has spread to their lymph nodes, lower rates of survival and higher rates of recurrence following surgery for pancreatic cancer, according to a report in the March issue of Archives of Surgery, one of the JAMA/Archives journals.

16 Mar 2009

Updated guidelines for ovarian cancer

Improvements in screening and early detection remains the key for women with ovarian cancer according to Robert J. Morgan, MD, of City of Hope Comprehensive Cancer Center and chair of the NCCN Guidelines Panel for Ovarian Cancer.

16 Mar 2009

Alzheimer's disease neuroimaging initiative announces completion of genome-wide analysis

Researchers announced today that a high-density genome wide analysis of participants in the Alzheimer's Disease Neuroimaging Initiative (ADNI; www.adni-info.org) is more than 95% complete and that data will be shared with scientists around the world for further analysis.

16 Mar 2009

Study reinforces the importance of healthy living for women

Women who maintain a healthy weight and who have lower perceived stress may be less likely to have chromosome changes associated with aging than obese and stressed women, according to a pilot study that was part of the Sister Study.

16 Mar 2009

New measure for the malignancy of melanoma

Every tumor, starting from a size of a few millimeters, depends on a supply of nutrients and oxygen.

12 Mar 2009

New project to develop blood tests for heart disease and stroke

The landmark Framingham Heart Study (FHS) is launching a major initiative to discover risk factors and markers that could lead to new blood tests to identify individuals at high risk of heart disease and stroke.

12 Mar 2009

Test successfully identifies arrhythmogenic right ventricular cardiomyopathy

11 Mar 2009

New test successfully identifies arrhythmogenic right ventricular cardiomyopathy

A study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated that a new immunohistochemical test is reliable in diagnosing a dangerous arrhythmic heart disease known as arrhythmogenic right ventricular cardiomyopathy (ARVC.) Reported in the March 12 issue of The New England Journal of Medicine ( NEJM ), the new findings offer the possibility of a highly sensitive and specific means of identifying this life- threatening condition at an early stage, when it can be treated with by implanting a cardiac defibrillator.

11 Mar 2009

Low levels of vitamin D linked to several risk factors in teenagers

Low levels of vitamin D were associated with an increased risk of high blood pressure, high blood sugar and metabolic syndrome in teenagers, researchers reported at the American Heart Association's 49th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

11 Mar 2009

Trends in heart attack explained

Explaining trends in heart attack: prevention has improved, mortality rates are down, hospitalisation remains the same

11 Mar 2009

Alzheimer's marker amyloid beta 42 linked to brain damage

Researchers at Washington University School of Medicine in St. Louis have linked a potential indicator of Alzheimer's disease to brain damage in humans with no signs of mental impairment.

11 Mar 2009

Tiny samples could yield big predictive markers for pancreatic cancer

A handful of proteins, detected in incredibly tiny amounts, may one day help doctors distinguish between a harmless lesion in the pancreas and a potentially deadly one, say researchers at Fox Chase Cancer Center.

11 Mar 2009

Breath or urine analysis with optical gas sensors may detect cancer, diabetes

A future sensor may take away a patient's breath while simultaneously determining whether the patient has breast cancer, lung cancer, diabetes or asthma.

11 Mar 2009

Brain damage found in cognitively normal people with Alzheimer's marker

Researchers at Washington University School of Medicine in St. Louis have linked a potential indicator of Alzheimer's disease to brain damage in humans with no signs of mental impairment.

11 Mar 2009

Color of wine makes no difference when it comes to breast-cancer

The largest study of its kind to evaluate the effect of red versus white wine on breast-cancer risk concludes that both are equal offenders when it comes to increasing breast-cancer risk.

10 Mar 2009

City kids may breathe easier in the country

Children with asthma have an easier time breathing if they spend even a few days in the country, safeguarded from urban air pollution, a study led by Giovanni Piedimonte, M.D., professor and chairman of the Department of Pediatrics at the West Virginia University School of Medicine, finds.

10 Mar 2009