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Study uncovers novel mechanism that helps govern regulated gene expression

A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression. The study was published on line in advance of print November 10 in the journal Nature Structural and Molecular Biology.

13 Nov 2013

Scientists use new technology to study whole genome to find the cause of genetic disease

For the first time, scientists have used new technology which analyses the whole genome to find the cause of a genetic disease in what was previously referred to as "junk DNA".

11 Nov 2013

A*STAR scientists discover potential target to weed out progression of cancer

Scientists at A*STAR have discovered an enzyme, Wip1 phosphatase, as a potential target to weed out the progression of cancer. Although studies in the past have revealed that this enzyme plays a critical role in regulating the budding of tumours, scientists have for the first time unearthed a mechanism for its mode of action.

10 Nov 2013

Genetic variations in African Americans with kidney disease contribute to rapid decline in kidney function

New research provides direct evidence that genetic variations in some African Americans with chronic kidney disease contribute to a more rapid decline in kidney function compared with white Americans.

10 Nov 2013

Cancer research leaders announce the opening of ICGC-TCGA-DREAM SMC Challenge

Cancer research leaders from the Ontario Institute for Cancer Research and the University of California, Santa Cruz, in collaboration with Sage Bionetworks and IBM's DREAM, will announce tomorrow the opening of the ICGC-TCGA-DREAM Somatic Mutation Calling Challenge at the Sixth Annual RECOMB/ISCB conference.

8 Nov 2013

New computational method quickly orders DNA sequencing information along entire chromosomes

A new computational method has been shown to quickly assign, order and orient DNA sequencing information along entire chromosomes. The method may help overcome a major obstacle that has delayed progress in designing rapid, low-cost -- but still accurate -- ways to assemble genomes from scratch.

8 Nov 2013

New study uses genomic sequencing to develop treatments for castration-resistant prostate cancer

A new study at Mayo Clinic is using genomic sequencing to develop customized treatments for men with castration-resistant prostate cancer, a progressive and incurable stage of prostate cancer, which no longer responds to hormone therapies that stop or slow testosterone production.

7 Nov 2013

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

New research shows that chronic stress changes gene activity in immune cells before they reach the bloodstream. With these changes, the cells are primed to fight an infection or trauma that doesn't actually exist, leading to an overabundance of the inflammation that is linked to many health problems.

6 Nov 2013

AMP 2013 to focus on genomics, proteomics, informatics, reimbursement and optimization of patient care

AMP will host its largest ever annual meeting next week with an expected attendance of more than 1,700 molecular diagnostic professionals plus 1,300 representatives from more than 180 exhibiting companies. With more than 25 hours of educational sessions and 350 poster presentations, the AMP 2013 Annual Meeting is the premier source for educational information on all things molecular.

5 Nov 2013

Scientists make seminal breakthrough in understanding molecular basis of bile duct cancer

A team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, Fundeni Clinical Institute (Romania) and Koen Kaen University (Thailand), have made a seminal breakthrough in understanding the molecular basis of bile duct cancer or cholangiocarcinoma, a rare but highly lethal form of liver cancer.

4 Nov 2013

Scientists find surprising degree of variation among genomes of individual neurons

It was once thought that each cell in a person's body possesses the same DNA code and that the particular way the genome is read imparts cell function and defines the individual. For many cell types in our bodies, however, that is an oversimplification.

4 Nov 2013

Next-generation sequencing may help discover genetic changes that might lead to cancer

A pilot study led by the Translational Genomics Research Institute and the Virginia G. Piper Cancer Center at Scottsdale Healthcare shows that, even for patients with advanced and rapidly transforming cancer, researchers can find potential therapeutic targets using the latest advances in genomic sequencing.

31 Oct 2013

Reduced SMG1 protein expression may contribute to neurological disorders

The absence of a protein called SMG1 could be a contributing factor in the development of Parkinson's disease and other related neurological disorders, according to a study led by the Translational Genomics Research Institute.

31 Oct 2013

International researchers identify 11 new genes linked to Alzheimer's disease

An international group of researchers has identified 11 new genes that offer important new insights into the disease pathways involved in Alzheimer's disease. The highly collaborative effort involved scanning the DNA of over 74,000 volunteers-the largest genetic analysis yet conducted in Alzheimer's research-to discover new genetic risk factors linked to late-onset Alzheimer's disease, the most common form of the disorder.

28 Oct 2013

Researchers study genetic factors associated to metabolic syndrome

Researchers from the Institute of Genomic Medicine carried out a study on genetic factors that can be associated to metabolic syndrome, main trigger of cardiovascular diseases, type II diabetes and obesity, with the goal of identifying high risk populations and influence its treatment in the most effective way.

25 Oct 2013

McGill online game expands to connect global scientific community with citizen scientists

Over the past three years, 300,000 gamers have helped scientists with genomic research by playing Phylo, an online puzzle game. Now J-r-me Waldisp-hl, the McGill computer science professor and his colleagues, who developed the game are making this crowd of players available to scientists around the globe.

25 Oct 2013

Gene-diet interaction may shed light on increased risk of colorectal cancer linked with meat consumption

A newly discovered potential gene-diet interaction for colorectal cancer was reported today (Thursday, Oct. 24) at the American Society of Human Genetics 2013 meeting in Boston.

25 Oct 2013

New report explains occurrence of breast cancer in women with normal BRCA genes

Since 1994, many thousands of women with breast cancer from families severely affected with the disease have been tested for inherited mutations in BRCA1 and BRCA2. The vast majority of those patients were told that their gene sequences were normal.

25 Oct 2013

Study identifies gene that raises risk for colorectal cancer from eating red or processed meat

A common genetic variant that affects 1 in 3 people significantly increases the risk of colorectal cancer from the consumption of red meat and processed meat, according to a study presented today at the annual American Society of Human Genetics 2013 meeting, the largest gathering of human geneticists in the world.

25 Oct 2013

Startup Wins Five-Year Exclusive License To Decode Genetics Platform

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23 Oct 2013

Genomic News and Research

Study uncovers novel mechanism that helps govern regulated gene expression

Scientists use new technology to study whole genome to find the cause of genetic disease

A*STAR scientists discover potential target to weed out progression of cancer

Genetic variations in African Americans with kidney disease contribute to rapid decline in kidney function

Cancer research leaders announce the opening of ICGC-TCGA-DREAM SMC Challenge

New computational method quickly orders DNA sequencing information along entire chromosomes

New study uses genomic sequencing to develop treatments for castration-resistant prostate cancer

Research: Chronic stress changes gene activity in immune cells before reaching bloodstream

AMP 2013 to focus on genomics, proteomics, informatics, reimbursement and optimization of patient care

Scientists make seminal breakthrough in understanding molecular basis of bile duct cancer

Scientists find surprising degree of variation among genomes of individual neurons

Next-generation sequencing may help discover genetic changes that might lead to cancer

Reduced SMG1 protein expression may contribute to neurological disorders

International researchers identify 11 new genes linked to Alzheimer's disease

Researchers study genetic factors associated to metabolic syndrome

McGill online game expands to connect global scientific community with citizen scientists

Gene-diet interaction may shed light on increased risk of colorectal cancer linked with meat consumption

New report explains occurrence of breast cancer in women with normal BRCA genes

Study identifies gene that raises risk for colorectal cancer from eating red or processed meat

Startup Wins Five-Year Exclusive License To Decode Genetics Platform

Genetics & Genomics - Second Edition eBook

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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