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IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

A team of researchers from Indiana University and Memorial Sloan Kettering Cancer Center have been awarded a $4.1 million National Cancer Institute "Cancer Moonshot" grant to develop immunotherapy treatments for cancer in children and adolescents, especially those with leukemia.

31 May 2019

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

A team of researchers led by Kazuhiro Suzuki from the Immunology Frontier Research Center at Osaka University discovered the COMMD3/8 complex as a molecule involved in immune cell migration, clarifying that the complex plays a critical role in the establishment of immune responses.

31 May 2019

Newly discovered mechanism of enzyme links circadian clock and fat metabolism

The enzyme Nocturnin, which governs daily tasks such as fat metabolism and energy usage, works in an entirely different way than previously thought, reported a team of researchers at Princeton University.

30 May 2019

Researchers find new molecular targets for fighting autoimmunity

BRCA--the family of DNA-repair proteins associated with breast, ovarian prostate, and pancreatic cancers--interacts with a multipart, molecular complex that is also responsible for regulating the immune system.

30 May 2019

Researchers discover healthy, stress-busting fat in soil-dwelling bacteria

Thirty years after scientists coined the term "hygiene hypothesis" to suggest that increased exposure to microorganisms could benefit health, University of Colorado Boulder researchers have identified an anti-inflammatory fat in a soil-dwelling bacterium that may be responsible.

29 May 2019

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers have discovered a new genetic variant responsible for blood vessel dysregulation in the development of age-related macular degeneration (AMD).

29 May 2019

Study: Immune discovery may improve cancer therapies

Cancer therapies that use immune cells to trigger the body to attack tumors could be improved by a molecule that boosts their function.

29 May 2019

Research could lead to new treatments for people with autoimmune disorders

The immune system is programmed to rid the body of biological bad guys--like viruses and dangerous bacteria--but its precision isn't guaranteed. In the tens of millions of Americans suffering from autoimmune diseases, the system mistakes normal cells for malicious invaders, prompting the body to engage in self-destructive behavior.

29 May 2019

Lugdunin in the human nose has strong antimicrobial properties against S. aureus

Antibiotic-resistant bacteria are an increasing health threat, making new antibiotics essential. German researchers have recently had a breakthrough: they discovered lugdunin in the human nose--a new kind of cyclic peptide that comes from the bacterium Staphylococcus lugdunensis and has strong antimicrobial properties against Staphylococcus aureus, among others.

29 May 2019

Study may help solve the mystery of how to detect and deal with deep vein thrombosis

It's the third deadliest cardiovascular diagnosis, but doctors are still often stumped to explain why 40% of patients experience unprovoked venous thromboembolism. And after a patient has dealt with these dangerous blood clots once, a second and subsequent events become much more likely.

29 May 2019

PCRF awards £1.2M grants for new research projects tackling pancreatic cancer

Seven innovative research projects tackling pancreatic cancer have been awarded grants totalling £1.2M by the UK medical research charity, Pancreatic Cancer Research Fund.

28 May 2019

Synthetic CBD alternative effectively treats seizures in rats

A synthetic, non-intoxicating analogue of cannabidiol is effective in treating seizures in rats, according to research by chemists at the University of California, Davis.

28 May 2019

Researchers discover unexpected survival mechanism of a subset of cancer cells

Embedded at the end of chromosomes are structures called "telomeres" that in normal cells become shorter as cells divide. As the shortening progresses it triggers cell proliferation arrest or death. Cancer cells adopt different strategies to overcome this control mechanism that keeps track of the number of times that a cell has divided.

28 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

A new study from the University of Minnesota Medical School clarifies how the three-dimensional organization of the genome is regulated at the onset of skeletal muscle formation.

25 May 2019

New neurons continue to form in old age, even in people with Alzheimer's disease

In a new study from the University of Illinois at Chicago, researchers examining post-mortem brain tissue from people ages 79 to 99 found that new neurons continue to form well into old age.

25 May 2019

Longas offers Morphoseq technology for highly accurate long read sequencing on short read NGS platforms

Longas Technologies Pty Ltd, a developer of Next Generation Sequencing technologies, has provided details on its Morphoseq library prep and associated software technology at the ‘Sequencing, Finishing and Analysis in the Future’ meeting, May 21 – 23, Santa Fe, NM, USA, that enables long read sequencing on short read NGS platforms.

23 May 2019

Scientists identify target to ‘tone down’ hyper-active immunity to influenza infection

For most people, the influenza A virus, commonly known as the flu, is cleared from the body by our own immune system.

23 May 2019

Newly discovered molecules safely halt the gene editing process

Scientists have discovered two non-toxic molecules that safely halt the CRISPR-Cas9 gene editing process.

22 May 2019

Inhibition of CRMP2 phosphorylation promotes axonal regeneration after optic nerve injury

A new study by Professor Toshio Ohshima of Waseda University has found that the inhibition of phosphorylation of collapsing response mediator protein 2, a microtubule-binding protein, suppresses degeneration of nerve fibers and promotes its regeneration after optic nerve injury.

22 May 2019

Molecule News and Research

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

Newly discovered mechanism of enzyme links circadian clock and fat metabolism

Researchers find new molecular targets for fighting autoimmunity

Researchers discover healthy, stress-busting fat in soil-dwelling bacteria

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Study: Immune discovery may improve cancer therapies

Research could lead to new treatments for people with autoimmune disorders

Lugdunin in the human nose has strong antimicrobial properties against S. aureus

Study may help solve the mystery of how to detect and deal with deep vein thrombosis

PCRF awards £1.2M grants for new research projects tackling pancreatic cancer

Synthetic CBD alternative effectively treats seizures in rats

Researchers discover unexpected survival mechanism of a subset of cancer cells

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

New neurons continue to form in old age, even in people with Alzheimer's disease

Longas offers Morphoseq technology for highly accurate long read sequencing on short read NGS platforms

Scientists identify target to ‘tone down’ hyper-active immunity to influenza infection

Newly discovered molecules safely halt the gene editing process

Inhibition of CRMP2 phosphorylation promotes axonal regeneration after optic nerve injury

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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