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Genzyme third quarter revenue increases to $1.0 billion

Genzyme Corp. today reported third-quarter earnings growth driven by increased shipments of Cerezyme® (imiglucerase for injection). Patients in the United States began returning to normal dosing levels last month, and patients globally are expected to be able to do so this quarter. Earnings growth in the third quarter was also driven by strong revenue from Lumizyme™ (alglucosidase alfa) and cost reduction measures.

21 Oct 2010

Alexion announces results of eculizumab two open-label Phase 2 studies for aHUS treatment

Alexion Pharmaceuticals, Inc. today announced that its two open-label Phase 2 studies investigating eculizumab (Soliris) as a treatment for patients with atypical Hemolytic Uremic Syndrome (aHUS) have met the primary and key secondary endpoints with high clinical and statistical significance, in interim analyses.

21 Oct 2010

Genzyme reports results of Clolar combination Phase 3 trial in adult AML

Genzyme Corporation announced results today from its CLASSIC I phase 3 trial comparing Clolar® (clofarabine) in combination with the chemotherapy agent cytarabine (ara-c) to cytarabine plus placebo in relapsed-refractory adult acute myeloid leukemia (AML).

21 Oct 2010

ThermoGenesis enters licensing agreement with BioParadox for Res-Q technology

ThermoGenesis Corp. a leading supplier of innovative products and services that process and store adult stem cells, said today it has entered into a license and distribution agreement for its Res-Q 60 BMC (Res-Q) System with BioParadox, Inc., a newly-formed regenerative medicine company focusing on point-of-care cardiovascular therapies.

20 Oct 2010

Amgen to review study results of ESA in chronic renal failure patients with FDA and CRDAC

Amgen will review the results from TREAT (the Trial to Reduce Cardiovascular Events with Aranesp® Therapy) and will discuss how these results inform the appropriate use of erythropoiesis-stimulating agents (ESAs) for chronic renal failure (CRF) patients at today's meeting of the Food and Drug Administration's (FDA) Cardiovascular and Renal Drugs Advisory Committee (CRDAC).

19 Oct 2010

Researchers explore impact of various factors on increasing rates of Clostridium difficile infection

In five different studies presented at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio, researchers explored the impact of various factors on increasing rates of Clostridium difficile infection (C. difficile), such as the use of proton pump inhibitors (PPIs) and the substantial increase in antibiotic use due to new National Hospital Quality Measures; strategies to combat high rates of C. difficile infections; and cutting‐edge treatments for this potentially deadly-and quite common-infection.

19 Oct 2010

Study indicates vitamin D deficiency may increase lung transplant rejection

Vitamin D deficiency is associated with a significant increase in lung transplant rejection, according to research conducted at Loyola University Health System (LUHS). These data were presented Monday at The American Society for Bone and Mineral Research 2010 annual meeting in Toronto, Ontario.

19 Oct 2010

Candidates turn health reform volume up as midterms near

A number of candidates for federal and state office are sounding off on how they view health reform.

18 Oct 2010

BARACLUDE sNDA receives FDA approval for treatment of CHB patients with decompensated liver disease

Bristol-Myers Squibb Company announced today that the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) of BARACLUDE for the treatment of chronic hepatitis B (CHB) in adult patients with decompensated liver disease.

18 Oct 2010

Change to WA organ donor laws tabled

Under a new proposal Western Australia could become the first state in Australia to introduce ‘opt-out’ organ donor laws. At present people need to opt in to be a part of national organ donor register. However, only 16 per cent of West Australians have signed to date. Under this proposal all West Australians will automatically donate their organs after they die unless they register their objection.

17 Oct 2010

UCSD certification for SynCardia temporary Total Artificial Heart to commence: SynCardia Systems

SynCardia Systems, Inc. announced today that the University of California, San Diego (UCSD), led by Stuart W. Jamieson, M.B., F.R.C.S. (photo), Head of Cardiothoracic Surgery, will begin certification to implant the SynCardia temporary Total Artificial Heart. Efforts to bring the Total Artificial Heart to UCSD were led by world renowned heart surgeon Dr. Jack Copeland, who joined the faculty in July.

15 Oct 2010

Experts use multi-disciplinary approach to provide innovative care for children

Liver tumors affect more than 300 children in the United States each year and management of these children requires coordinated comprehensive care from experts in many disciplines. To answer this problem, Texas Children's Hospital and Baylor College of Medicine announced today the formation of a new Liver Tumor Center that brings together renowned specialists in all aspects of liver cancer who will utilize a multi-disciplinary approach to provide the most comprehensive and innovative care for children afflicted with these diseases.

15 Oct 2010

MRI-guided laser ablation offers way to kill tumors

Physicians at Mayo Clinic's Florida campus are among the first in the nation to use a technique known as MRI-guided laser ablation to heat up and destroy kidney and liver tumors. So far, five patients have been successfully treated meaning no visible tumors remained after the procedure.

15 Oct 2010

Genzyme reports five-year patient data from Phase 2 multiple sclerosis trial

Genzyme Corporation today reported five-year patient data from its completed Phase 2 multiple sclerosis (MS) trial. This sub-group analysis found that nearly 90 percent of alemtuzumab-treated patients were free of sustained accumulation of disability, and that patients receiving alemtuzumab also maintained improved mean disability scores and a low risk of relapse over the 60-month follow-up period.

15 Oct 2010

Moores Cancer Center files IND application for topical NexACT-based formulation

Apricus Biosciences, backed by a revenue generating CRO business and seeking to leverage its multi-route NexACT drug delivery technology and internal pipeline through out-licensing partnerships, today announced that the Moores Cancer Center at the University of California San Diego (UCSD) has filed an Investigational New Drug Application with the U.S. Food & Drug Administration ("FDA") for approval to test Nupen, Apricus Bio's proprietary, topical NexACT-based formulation of filgrastim (Neupogen).

15 Oct 2010

Study confirms long term survival benefit of ELAD bioartificial liver support system in Chinese ACLF patients

Vital Therapies, Inc., today announced that a poster is being presented at the American Association for the Study of Liver Diseases (AASLD) meeting in Boston on Tuesday, November 2nd. It confirms that previously reported findings of improved transplant free survival (TFS) in Chinese subjects with acute-on-chronic liver failure (ACLF) treated with the ELAD® bioartificial liver support system are maintained for up to three years.

14 Oct 2010

Drugs that restore mitochondria function may treat Alzheimer's disease at early stages: Research

Before Alzheimer's patients experience memory loss, the brain's neurons have already suffered harm for years. A new study in mouse models by researchers at Columbia University Medical Center has found that the brain's mitochondria, the powerhouses of the cell, are one of the earliest casualties of the disease. The study, which appeared in the online Early Edition of PNAS, also found that impaired mitochondria then injure the neurons' synapses, which are necessary for normal brain function.

14 Oct 2010

Mesoblast broadens cancer indications for bone marrow transplant product

Australian regenerative medicine company Mesoblast Limited (ASX: MSB, USOTC: MBLTY) today announced that it is broadening the oncology applications of its "off-the-shelf" cell product for expansion of haematopoietic stem cells in patients with blood cancers. Building on the recent clinical success of Mesoblast’s proprietary cell product for expansion of cord blood, the Company will now address new markets where expansion of haematopoietic stem cells can make a meaningful impact on clinical outcomes, including diseases such as multiple myeloma.

13 Oct 2010

Beta-Pro expands operations to meet increasing demand in $2 billion hepatocyte market

Beta-Pro LLC, announced today that it has expanded its operations to accommodate increasing demands from pharmaceutical drug discovery and research institutes in the $2 billion hepatocyte market. The human cellular sciences company now manages extensive laboratory facilities in the University of Virginia Research Park in Charlottesville, Virginia.

13 Oct 2010

New, longer lasting LVAD implanted in Canadian heart-failure patient

In a Canadian first, the Peter Munk Cardiac Centre used a new kind of left ventricular assist device (LVAD) to treat a patient with advanced heart failure. The new device is longer lasting than older generation LVADs and may eliminate the need for a second LVAD - a major drawback with the old technology.

13 Oct 2010

Transplant News and Research

Genzyme third quarter revenue increases to $1.0 billion

Alexion announces results of eculizumab two open-label Phase 2 studies for aHUS treatment

Genzyme reports results of Clolar combination Phase 3 trial in adult AML

ThermoGenesis enters licensing agreement with BioParadox for Res-Q technology

Amgen to review study results of ESA in chronic renal failure patients with FDA and CRDAC

Researchers explore impact of various factors on increasing rates of Clostridium difficile infection

Study indicates vitamin D deficiency may increase lung transplant rejection

Candidates turn health reform volume up as midterms near

BARACLUDE sNDA receives FDA approval for treatment of CHB patients with decompensated liver disease

Change to WA organ donor laws tabled

UCSD certification for SynCardia temporary Total Artificial Heart to commence: SynCardia Systems

Experts use multi-disciplinary approach to provide innovative care for children

MRI-guided laser ablation offers way to kill tumors

Genzyme reports five-year patient data from Phase 2 multiple sclerosis trial

Moores Cancer Center files IND application for topical NexACT-based formulation

Study confirms long term survival benefit of ELAD bioartificial liver support system in Chinese ACLF patients

Drugs that restore mitochondria function may treat Alzheimer's disease at early stages: Research

Mesoblast broadens cancer indications for bone marrow transplant product

Beta-Pro expands operations to meet increasing demand in $2 billion hepatocyte market

New, longer lasting LVAD implanted in Canadian heart-failure patient

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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