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The atomic-level structure of DNA polymerase delta – the enzyme behind DNA replication

A new study has revealed how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that can be transmitted through the generations.

4 Oct 2019

New imaging systems can help diagnose heart disease

Researcher and professor Lasse Løvstakken starts a video on his computer screen. We're in the eye of a storm. It looks almost like a hurricane approaching a coastline.

30 Sep 2019

PWSA (USA) announces support for H.R.4144 - Ending the Diagnostic Odyssey Act of 2019

Today, PWSA (USA) announced its support for H.R.4144 - Ending the Diagnostic Odyssey Act of 2019, a bill to enable States to better provide access to whole genome sequencing clinical services for certain undiagnosed children under the Medicaid program, and for other purposes.

27 Sep 2019

Researchers uncover fundamental difference in how DNA is held together

Researchers have made a fundamental discovery about the structure of DNA; the structure is held together by water, not hydrogen alone.

23 Sep 2019

DNA origami: creating DNA-based nanomachines

DNA-based nanomachines are being created by DNA origami in several ways to create mechanical force at the scale of picoNewtons.

19 Sep 2019

Caring contacts reduce the odds of suicide attempt

A soldier named Jerome Motto received caring letters from home in World War II. They helped boost his spirits and later led to one of the nation's first successful suicide interventions.

11 Sep 2019

Blood sugar levels linked to DNA damage and cancer in diabetics

Increased blood sugar levels in diabetics could damage DNA and make the genome unstable, increasing the risk of certain cancers.

26 Aug 2019

Individually packed sterile assay microplates for optimized tissue culture cell growth

Porvair Sciences announces its complete range of Krystal (TM) clear bottomed assay microplates is now available individually packed and sterilized for optimized tissue culture cell growth or non-sterile for assay development.

From Porvair Sciences Limited 26 Aug 2019

New method prevents the release of synthetic DNA from genetically modified cells

The method prevents a gene that encodes a synthetic protein from spreading into the wild and stabilizes it so that it cannot mutate and lose its function.

21 Aug 2019

Researchers analyze precise mechanism of binding reaction in PUVA therapy

The term 'PUVA' stands for 'psoralen' and 'UV-A radiation'. Psoralens are natural plant-based compounds that can be extracted from umbelliferous plants such as giant hogweeds.

21 Aug 2019

IDT launches high quality, ready-to-use custom oligo pools

Continuing its mission to advance biological research worldwide, Integrated DNA Technologies has launched oPools Oligo Pools – ready-to-use pools of high quality DNA oligonucleotides (oligos) up to 350 nucleotides in length.

From Integrated DNA Technologies 16 Aug 2019

Biomarkers reveal increase in thyroid cancer incidence among WTC responders

The incidence of thyroid cancer among first responders who volunteered or were employed as firefighters, rescue personnel and cleanup workers at Ground Zero in New York on or after September 11, 2001, is three times higher than that in the general population.

5 Aug 2019

New CRISPR tool enhances RNA editing

CRISPR-based tools helped revolutionize the ability to target genetic mutations linked to disease development. Such tools focus on using the enzymes Cas9 and Cas12 to target DNA, and Cas13 to target RNA. Now, scientists used a new CRISPR platform that expands the capabilities of RNA editing.

29 Jul 2019

UV-DDB protein scouts DNA damage and oversees repair

In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of Pittsburgh have gotten a glimpse of how one protein in particular keeps DNA damage in check.

22 Jul 2019

Research team detects novel mechanism of inheritance

Non-Mendelian, oligogenic inheritance could bean unrecognized and important element for occurrence ofhereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and cause progressive blindness.

18 Jul 2019

New gene-editing protocol allows perfect mutation-effect matching

Geneticists have long awaited the ability to simply knock out or add a single gene here and there, as desired, with accuracy and efficiency, and then study the exact consequences caused by the loss or addition of that genetic information.

9 Jul 2019

Intermittent fasting may protect against type 2 diabetes

Intermittent fasting is known to improve sensitivity to the blood glucose-lowering hormone insulin and to protect against fatty liver.

2 Jul 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019