Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

TSRI scientists discover potential way to stop meth relapse

New research from The Scripps Research Institute suggests that the reason methamphetamine users find it so hard to quit—88 percent of them relapse, even after rehab—is that meth takes advantage of the brain's natural learning process.

31 Mar 2017

Researchers propose novel theory of how some cancers circumvent killing power of targeted therapies

Nearly 50 years into the "war" on cancer, doctors possess weapons that once would have seemed magical in their tumor-killing specificity.

29 Mar 2017

Study identifies how BPA may encourage inflammatory breast cancer growth

The chemical bisphenol A, or BPA, appears to aid the survival of inflammatory breast cancer cells, revealing a potential mechanism for how the disease grows, according to a study led by researchers in the Department of Surgery at Duke University School of Medicine and the Duke Cancer Institute.

28 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

LCSB researchers identify how the body influences differentiation of progenitor cells

Stem cells are unspecialised cells that can develop into any type of cell in the human body. So far, however, scientists only partially understand how the body controls the fate of these all-rounders, and what factors decide whether a stem cell will differentiate, for example, into a blood, liver or nerve cell.

15 Mar 2017

Researchers explore genomic underpinnings of obesity in continental Africans and African-Americans

An international team of researchers has conducted the first study of its kind to look at the genomic underpinnings of obesity in continental Africans and African-Americans.

13 Mar 2017

Scientists pinpoint key biological mechanism that can prevent proliferation of insulin-producing cells

If you become resistant to insulin, a condition that is a precursor to type 2 diabetes, your body tries to compensate by producing more of the "beta" cells in the pancreas that produce the critical hormone.

9 Mar 2017

New research program aims to produce all human secreted proteins

A new research program has been launched to produce all the human secreted proteins in mammalian cell factories. The program aims to facilitate studies of this important class of proteins, which are involved in many human diseases.

7 Mar 2017

Study unravels protective mechanism that allows fruit flies to lay fewer eggs during bacterial infection

A protective mechanism that allows fruit flies to lay fewer eggs in response to bacterial infection is explained in a study published in the journal eLife.

7 Mar 2017

Researchers reveal biological pathways involved in diabetic kidney disease

Diabetes is a leading cause of kidney disease, a serious, often fatal complication that is difficult to diagnose in early, potentially treatable stages.

24 Feb 2017

U of T study uncovers gene that may play key role in obesity

A University of Toronto (U of T) study on fruit flies has uncovered a gene that could play a key role in obesity in humans.

22 Feb 2017

Cancer cells adapt nerve cell mechanisms to fuel aggressive tumor growth and spread

How we think and fall in love are controlled by lightning-fast electrochemical signals across synapses, the dynamic spaces between nerve cells. Until now, nobody knew that cancer cells can repurpose tools of neuronal communication to fuel aggressive tumor growth and spread.

21 Feb 2017

Changes in size of mitochondria in subset of brain cells could be key to maintaining blood sugar

Keeping blood sugar levels within a safe range is key to managing both type 1 and type 2 diabetes. In a new finding that could lead to fewer complications for diabetes patients, Yale School of Medicine researchers have found that changes in the size of mitochondria in a small subset of brain cells play a crucial role in safely maintaining blood sugar levels.

15 Feb 2017

Mice study shows how WAVE1 protein regulates the brain's response to cocaine

Cocaine is one of the most addictive substances known to man, and for good reason: By acting on levels of the "feel-good" chemical dopamine, it produces a tremendous sensation of euphoria.

15 Feb 2017

Exosome isolation using ultracentrifugation

In the outpatient clinic and lab, our research studies aim to understand biological functions of exosomes and membrane particles.

From Beckman Coulter Life Sciences - Centrifugation 9 Feb 2017

Transporters of thyroid hormones play key role in development of the brain, study finds

Thyroid hormones are very important for the development of the brain. And when the transporters of these hormones are not functioning properly, the consequences for the development of the cerebellum or 'the little brain' are very serious.

6 Feb 2017

Nicotine creates cascade of effects in the brain that get worse over time

The first period of nicotine abstinence proceeded as expected. The surprise came after three months when the lab rats suddenly became fearless and sought out well-lighted areas that prey animals normally avoid. At the same time, signaling in the brain's reward system changed, as shown by a study at Sahlgrenska Academy.

2 Feb 2017

Characterizing the Brain - Cell by Cell

My group develops approaches to study cell-to-cell signaling in the brain – how the cells of the brain talk to each other. The brain is heterogeneous, probably more so than any other organ in our body, and many of its functions depend on the unique characteristics of these cells.

From Pittcon 23 Jan 2017

Researchers move one step closer to regenerating heart wall using stem cells

A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers.

12 Jan 2017

Mayo Clinic scientists identify key molecule that helps protect the central nervous system against sepsis

No effective therapy exists today for sepsis, an inflammatory storm that afflicts about 3 million Americans a year - killing up to half.

10 Jan 2017

Cell Signaling News and Research

Further Reading

TSRI scientists discover potential way to stop meth relapse

Researchers propose novel theory of how some cancers circumvent killing power of targeted therapies

Study identifies how BPA may encourage inflammatory breast cancer growth

LJI researchers unravel molecular underpinnings of exhausted T cells

LCSB researchers identify how the body influences differentiation of progenitor cells

Researchers explore genomic underpinnings of obesity in continental Africans and African-Americans

Scientists pinpoint key biological mechanism that can prevent proliferation of insulin-producing cells

New research program aims to produce all human secreted proteins

Study unravels protective mechanism that allows fruit flies to lay fewer eggs during bacterial infection

Researchers reveal biological pathways involved in diabetic kidney disease

U of T study uncovers gene that may play key role in obesity

Cancer cells adapt nerve cell mechanisms to fuel aggressive tumor growth and spread

Changes in size of mitochondria in subset of brain cells could be key to maintaining blood sugar

Mice study shows how WAVE1 protein regulates the brain's response to cocaine

Exosome isolation using ultracentrifugation

Transporters of thyroid hormones play key role in development of the brain, study finds

Nicotine creates cascade of effects in the brain that get worse over time

Characterizing the Brain - Cell by Cell

Researchers move one step closer to regenerating heart wall using stem cells

Mayo Clinic scientists identify key molecule that helps protect the central nervous system against sepsis

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo