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Study investigates multi-enzyme complex that plays key role in metabolism

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists at Martin Luther University Halle-Wittenberg (MLU) and TU Berlin have published their findings in the journal Cell Reports.

11 Feb 2021

New gut microbiome-based approach may have translational potential for cancer immunotherapy

Scientists from Nanjing University and the University of Macau have devised a new approach to extend the survival of transplanted probiotics in vivo, enhancing the efficacy of cancer chemo-/immunotherapies in mice.

11 Feb 2021

Could graphene be an effective antiviral platform against SARS-CoV-2?

The urgent need for novel therapeutics has spurred investigation into broad-spectrum inhibitors of viral infection and replication. A new study describes the antiviral activity of synthesized graphene platforms, pointing to new therapeutic approaches against this virus.

8 Feb 2021

Study finds structural similarities between SARS-CoV-2 and pangolin coronavirus

Scientists at the Francis Crick Institute have found important structural similarities between SARS-CoV-2 and a pangolin coronavirus, suggesting that a pangolin coronavirus could infect humans.

7 Feb 2021

Imaging SARS-CoV-2 with a helium ion microscope for the first time

Scientists at Bielefeld University's Faculty of Physics have succeeded for the first time in imaging the SARS-CoV-2 coronavirus with a helium ion microscope.

4 Feb 2021

Applications and Advantages of High-Speed AFM

AZoM talks to Professor Toshio Ando about his interest in high-speed AFM (HS-AFM) and how it can revolutionize observation of protein molecules.

From Bruker Nano Surfaces and Metrology 4 Feb 2021

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

Researchers from Osaka University have described the link between accurate protein folding and misfolding that can lead to the formation of amyloid fibers, which are implicated in neurodegenerative diseases

31 Jan 2021

Thread-based sensors can measure head movements in real time

Engineers at Tufts University have created and demonstrated flexible thread-based sensors that can measure movement of the neck, providing data on the direction, angle of rotation and degree of displacement of the head.

29 Jan 2021

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

A team of international scientists has recently revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with two heme metabolites, bilirubin and biliverdin, to escape the antibody-mediated host immune responses.

27 Jan 2021

Size of synapses determines the strength of information transmission

Nerve cells communicate with one another via synapses. Neuroscientists at the University of Zurich and ETH Zurich have now found that these connections seem to be much more powerful than previously thought.

21 Jan 2021

Scientists uncover elusive mechanism behind the most severe cases of blood disorder

With a name like glucose-6-phosphate dehydrogenase deficiency, one would think it is a rare and obscure medical condition, but that's far from the truth.

19 Jan 2021

Study reveals possible SARS-CoV-2 escape mutant that may re-infect immune individuals

A recent study by US researchers shows how the 501Y.V2 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), characterized by several mutations, is able to escape neutralization by present first-wave anti-SARS-CoV-2 antibodies and potentially re-infect COVID-19 convalescent individuals.

17 Jan 2021

Influenza drug enisamium a potential COVID-19 treatment

Researchers in Europe and the United States have demonstrated the potential of the influenza drug enisamium as a treatment for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

13 Jan 2021

New UK-derived SARS-CoV-2 variant does not affect neutralizing antibodies efficiency, study says

A team of scientists conducted structural analysis of a newly emerged UK variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They present evidence that suggests that while the new variant has increased infectivity it is not resistant to neutralizing antibodies.

13 Jan 2021

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a condition caused by the weakening of the heart muscle, affecting the ventricles (chambers in the heart that push blood around the body as it contracts).

13 Jan 2021

Researchers develop novel antibody fragments against SARS coronavirus-2

An international research team led by the University of Bonn (Germany) has identified and further developed novel antibody fragments against the SARS coronavirus-2. These "nanobodies" are much smaller than the classic antibodies used to treat US President Donald Trump, for example.

13 Jan 2021

Antigenic "supersite" could improve design of COVID-19 vaccines

Researchers in the United States have defined an antigenic “supersite” within the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could have important implications for the design of vaccines to protect against coronavirus disease 2019 (COVID-19).

12 Jan 2021

New fluorescence microscopy technique produces nanoscale 3D images of living cells

A new fluorescence microscopy technique has produced the world's first nanoscale 3D images of molecules in a whole, living cell, researchers at KTH Royal Institute of Technology reported.

12 Jan 2021

Researchers develop improved process for large-scale electron microscopy to visualize small structures

How are networks of neurons connected to make functional circuits? This has been a long-standing question in neuroscience. To answer this fundamental question, researchers from Boston Children's Hospital and Harvard Medical School developed a new way to study these circuits and in the process learn more about the connections between them.

12 Jan 2021

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

Development of an in vitro human-derived tissue model for studying virus infection and disease progression in the alveolar cells of the lungs responsible for oxygen and carbon dioxide exchange with the blood might enable the study of possible therapies for acute respiratory distress syndrome (ARDS) triggered by SARS-CoV-2.

11 Jan 2021

Electron Microscopy News and Research

Study investigates multi-enzyme complex that plays key role in metabolism

New gut microbiome-based approach may have translational potential for cancer immunotherapy

Could graphene be an effective antiviral platform against SARS-CoV-2?

Study finds structural similarities between SARS-CoV-2 and pangolin coronavirus

Imaging SARS-CoV-2 with a helium ion microscope for the first time

Applications and Advantages of High-Speed AFM

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

Thread-based sensors can measure head movements in real time

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

Size of synapses determines the strength of information transmission

Scientists uncover elusive mechanism behind the most severe cases of blood disorder

Study reveals possible SARS-CoV-2 escape mutant that may re-infect immune individuals

Influenza drug enisamium a potential COVID-19 treatment

New UK-derived SARS-CoV-2 variant does not affect neutralizing antibodies efficiency, study says

Study shows how cardiosphere-derived cells replenish damaged tissues in dilated cardiomyopathy

Researchers develop novel antibody fragments against SARS coronavirus-2

Antigenic "supersite" could improve design of COVID-19 vaccines

New fluorescence microscopy technique produces nanoscale 3D images of living cells

Researchers develop improved process for large-scale electron microscopy to visualize small structures

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

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